NIDCR Extramural Research Grants

NIH National Institute of Dental and Craniofacial Research (NIDCR) Extramural Research Programs is sponsored by National Institute of Dental and Craniofacial Research (NIDCR) / National Institutes of Health (NIH). NIDCR supports basic, translational, and clinical research in dental, oral, and craniofacial health and disease through grants and cooperative agreements. This includes research on orofacial pain, odontogenic diseases, oral microbiome, oral cancer, developmental biology, computational biology, dental repair, regenerative medicine, immunomodulatory oral science, precision medicine, clinical trials, patient health, epidemiology, oral and systemic health integration, salivary gland biology, rheumatic disease, and behavioral interventions.

Oral Diseases and Disorders Research - Research Centers is sponsored by Department of Health And Human Services. NIDCR extramural research provides research funds to support basic, translational, and clinical research in dental, oral, and craniofacial health and disease through grants and cooperative agreements that support scientists working in institutions throughout the United States and internationally. The extramural Research Centers programs plan, develop, and manage scientific priorities through portfolio analyses and consultation with stakeholders, encouraging the most promising discoveries and emerging technologies for rapid translation to clinical applications. Additionally, the Centers focus on a variety of diseases and conditions through clinical trials, epidemiologic studies, practice-based research, the HIV/AIDS and oral health program, and studies of oral health in all areas of NIDCR programmatic interest. The program encourages investigations that have the potential to translate findings into evidence-based clinical applications. The Integrative Biology and Infectious Diseases programs support basic and translational research programs on oral microbiology; salivary biology and immunology; oral and salivary gland cancers; neuroscience of orofacial pain and temporomandibular disorders; mineralized tissue physiology; dental biomaterials; and tissue engineering and regenerative medicine. The branch aims to accelerate progress in basic and translational research in these areas and further stimulate the discovery pipeline based on clinical needs. The Translational Genomics Research programs support basic and translational research in genetics, genomics, developmental biology, and data science toward the goal of improving dental, oral, and craniofacial health. The focus is on deciphering the genetic, molecular, and cellular mechanisms underlying dental, oral, and craniofacial development and anomalies. The Behavioral and Social Sciences Research programs support basic and applied research to promote oral health, to prevent oral diseases and related disabilities, and to improve management of craniofacial conditions, disorders, and injury. The program prioritizes mechanistic research that contributes to a cumulative science of behavior change, to maximize the rigor, relevance, and dissemination of efficacious behavior change interventions. The Clinical Research programs supports patient-oriented, population, and community based research aimed at improving the dental, oral, and craniofacial health of the nation. This listing is currently active. Program number: 93.DE2. Last updated on 2026-01-14.

Oral Diseases and Disorders Research - Other Research is sponsored by Department of Health And Human Services. NIDCR extramural research provides research funds to support basic, translational, and clinical research in dental, oral, and craniofacial health and disease through grants and cooperative agreements that support scientists working in institutions throughout the United States and internationally. The extramural Other Research programs plan, develop, and manage scientific priorities through portfolio analyses and consultation with stakeholders, encouraging the most promising discoveries and emerging technologies for rapid translation to clinical applications. The Integrative Biology and Infectious Diseases programs support basic and translational research programs on oral microbiology; salivary biology and immunology; oral and salivary gland cancers; neuroscience of orofacial pain and temporomandibular disorders; mineralized tissue physiology; dental biomaterials; and tissue engineering and regenerative medicine. The branch aims to accelerate progress in basic and translational research in these areas and further stimulate the discovery pipeline based on clinical needs. The Translational Genomics Research programs support basic and translational research in genetics, genomics, developmental biology, and data science toward the goal of improving dental, oral, and craniofacial health. The focus is on deciphering the genetic, molecular, and cellular mechanisms underlying dental, oral, and craniofacial development and anomalies. The Behavioral and Social Sciences Research programs support basic and applied research to promote oral health, to prevent oral diseases and related disabilities, and to improve management of craniofacial conditions, disorders, and injury. The program prioritizes mechanistic research that contributes to a cumulative science of behavior change, to maximize the rigor, relevance, and dissemination of efficacious behavior change interventions. The Clinical Research programs supports patient-oriented, population, and community based research aimed at improving the dental, oral, and craniofacial health of the nation. This listing is currently active. Program number: 93.DE3. Last updated on 2026-01-14.