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Find similar grantsNIH and CDC Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Required) is sponsored by National Institutes of Health. This opportunity supports mission-aligned projects and measurable outcomes.
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gov Maintenance Calendar View similar opportunities NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional) Department of Health and Human Services National Institutes of Health Document Type:Grants Notice Funding Opportunity Number:PA-27-101 Funding Opportunity Title:NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional) Opportunity Category:Discretionary Opportunity Category Explanation: Funding Instrument Type:Grant Category of Funding Activity:Health Expected Number of Awards: Assistance Listings:93.
233 -- National Center on Sleep Disorders Research 93. 242 -- Mental Health Research Grants 93. 273 -- Alcohol Research Programs 93.
307 -- Minority Health and Health Disparities Research 93. 313 -- NIH Office of Research on Women's Health 93. 350 -- National Center for Advancing Translational Sciences 93.
351 -- Research Infrastructure Programs 93. 393 -- Cancer Cause and Prevention Research 93. 394 -- Cancer Detection and Diagnosis Research 93.
395 -- Cancer Treatment Research 93. 837 -- Cardiovascular Diseases Research 93. 838 -- Lung Diseases Research 93.
839 -- Blood Diseases and Resources Research 93. 840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders 93. 847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research 93.
853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders 93. 855 -- Allergy and Infectious Diseases Research 93. 859 -- Biomedical Research and Research Training 93.
865 -- Child Health and Human Development Extramural Research 93.
867 -- Vision Research Cost Sharing or Matching Requirement:Yes Last Updated Date:Jun 01, 2026 Original Closing Date for Applications:Apr 05, 2029 Current Closing Date for Applications:Apr 05, 2029 Archive Date:Jun 04, 2029 Estimated Total Program Funding: Eligible Applicants:Small businesses Additional Information on Eligibility:Only United States small business concerns (SBCs) that have previously received an NIH SBIR or STTR Phase II award are eligible to submit applications for this opportunity.
Only one NIH Phase IIB Strategic Breakthrough award is allowed per project. This NOFO supports Renewal/Resubmission "Type 2" Applications from recipients with NIH Phase II SBIR/STTR awards that are submitted within the first six due dates following the expiration of their budget period. Refer to Section III.
Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
Unfunded international collaborations or unfunded foreign components, as defined in the NIH Grants Policy Statement, may be allowed. ## Additional Information Agency Name:National Institutes of Health Description:The NIH Phase IIB Strategic Breakthrough award bridges the funding gap between the end of a Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase II award and commercialization.
The Phase IIB Strategic Breakthrough provides previously funded NIH SBIR or STTR projects additional support for later-stage research and development (R&D). Link to Additional Information:[](https://www. grants.
gov/search-results-detail/359758) Grantor Contact Information:If you have difficulty accessing the full announcement electronically, please contact: NIH SEED (Small business Education and Entrepreneurial Development) NIH SEED (Small business Education and Entrepreneurial Development) ## Similar Opportunities (identified by AI) #### Health & Human Services * Frequently Asked Questions ## Your session will expire in 3 minutes.
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Yes — NIH and CDC Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Required) is offered by National Institutes of Health and this listing comes from Grants.gov, an official U.S. federal source. Federal applications generally require registrations (for example SAM.gov or an agency submission portal), so allow extra lead time.
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