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NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) is sponsored by National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), U.S. Food and Drug Administration (FDA). This program supports small businesses in innovative research with the potential for commercialization, particularly in health-related technologies.
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Opportunity Listing - NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) Agency: National Institutes of Health Assistance Listings: 93. 068 -- Chronic Diseases: Research, Control, and Prevention 93. 351 -- Research Infrastructure Programs 93.
083 -- Prevention of Disease, Disability, and Death through Immunization and Control of Respiratory and Related Diseases 93. 350 -- National Center for Advancing Translational Sciences 93. 273 -- Alcohol Research Programs 93.
867 -- Vision Research 93. 859 -- Biomedical Research and Research Training 93. 326 -- Strengthening Public Health through Surveillance, Epidemiologic Research, Disease Detection and Prevention 93.
847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research 93. 395 -- Cancer Treatment Research 93. 879 -- Medical Library Assistance 93.
073 -- Birth Defects and Developmental Disabilities - Prevention and Surveillance 93. 393 -- Cancer Cause and Prevention Research 93. 084 -- Prevention of Disease, Disability, and Death by Infectious Diseases 93.
233 -- National Center on Sleep Disorders Research 93. 394 -- Cancer Detection and Diagnosis Research 93. 173 -- Research Related to Deafness and Communication Disorders 93.
070 -- Environmental Public Health and Emergency Response 93. 121 -- Oral Diseases and Disorders Research 93. 136 -- Injury Prevention and Control Research and State and Community Based Programs 93.
840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders 93. 865 -- Child Health and Human Development Extramural Research 93. 846 -- Arthritis, Musculoskeletal and Skin Diseases Research 93.
837 -- Cardiovascular Diseases Research 93. 172 -- Human Genome Research 93. 279 -- Drug Use and Addiction Research Programs 93.
855 -- Allergy and Infectious Diseases Research 93. 286 -- Discovery and Applied Research for Technological Innovations to Improve Human Health 93. 113 -- Environmental Health 93.
839 -- Blood Diseases and Resources Research 93. 213 -- Research and Training in Complementary and Integrative Health 93. 103 -- Food and Drug Administration Research 93.
143 -- NIEHS Superfund Hazardous Substances_Basic Research and Education 93. 361 -- Nursing Research 93. 307 -- Minority Health and Health Disparities Research 93.
242 -- Mental Health Research Grants 93. 313 -- NIH Office of Research on Women's Health 93. 142 -- NIEHS Hazardous Waste Worker Health and Safety Training 93.
853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders 93. 838 -- Lung Diseases Research Last Updated: June 1, 2026 View version history on Grants. gov The Small Business Innovation Research (SBIR) program helps United States small business concerns (SBCs) bring scientific innovations to the marketplace.
The SBIR program supports feasibility studies to later research and development (R&D) needed to develop a commercial product. Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir. gov/apply) are eligible to submit applications for this opportunity.
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Unfunded international collaborations or unfunded foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
Grantor contact information NIH SEED (Small business Education and Entrepreneurial Development) NIH SEED (Small business Education and Entrepreneurial Development) File name Description Last updated PA-27-100-Revised-Full-Announcement. html PA-27-100-Revised-Full-Announcement.
html Link to additional information Funding opportunity number : Cost sharing or matching requirement : Funding instrument type : Opportunity Category Explanation : Category of Funding Activity : Your account requires additional identity verification.
According to the current listing, eligibility includes: Small business concerns (SBCs) with a majority ownership by U. S. citizens or permanent resident aliens. For-profit organizations other than small businesses are also eligible. Confirm the full requirements in the official notice before applying.
The published deadline was September 5, 2026, which has passed. Check the official notice for any future application windows before investing time in a proposal.
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) is funded by National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), U.S. Food and Drug Administration (FDA). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
The Small Business Innovation Research (SBIR) Program for CHIPS for America – CHIPS Metrology seeks applications from eligible applicants to explore the technical merit or feasibility of an innovative idea or technology with the aim of developing a viable product or service that will be introduced to the commercial microelectronics marketplace. This NOFO contains multiple topics on research projects for critically needed measurement services, tools, and instrumentation; innovative manufacturing metrologies; novel assurance and provenance technologies and advanced metrology research and development (R&D) testbeds to help secure U.S. leadership in the global semiconductor industry. Funding Opportunity Number: 2024-SBIR-CHIPS-01. Assistance Listing: 11.042,11.620. Funding Instrument: CA. Category: ST.
JobsOhio Small Business Grant is sponsored by JobsOhio. This grant offers financial support for real estate investments, equipment, and more for eligible projects and businesses. While broad in scope, if the autonomous scientific instrumentation or miniaturized microscope sensor payload directly leads to job creation or significant fixed-asset investment in Ohio, it could be relevant.
The HEAL Initiative's Studies to Enable Analgesic Discovery award (RFA-NS-25-023) puts federal money exactly where private capital won't go — the assay-building, screening, and hit-characterization stage of non-opioid pain therapeutics. It's a phased R61/R33, up to $350,000 in direct costs per year, with the next application deadline September 17, 2026. Here is how the two-phase structure works, who's eligible, and how to build a proposal that survives the R61-to-R33 milestone gate.
Read articleUSDA and HHS announced Harvest to Hallways on August 24, 2026: $50M in new cafeteria infrastructure funding on top of $20M in Equipment Assistance Grants, up to $25M more in Patrick Leahy Farm to School awards for FY2026, and $30M in HHS nutrition research. Each pot has a different applicant, a different route, and a different timeline. Here is how to position for all three before the notices post.
Read articleNOT-OD-26-098 consolidates NIH career development awards into four parent NOFOs (KR1, KC1, KS1, KT1), eliminates the Data Management and Sharing Plan for K applications, and stops supporting K awards that let the awardee lead their own clinical trial. The RFI closes September 30, 2026; the new structure hits due dates on or after October 12, 2027.
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