NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional)

NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional) is sponsored by National Institutes of Health (NIH) - Office of the Director (OD) with multiple participating organizations. This program encourages applications for collaborative international research projects that involve activities outside of the United States or partnerships with international collaborators.

Opportunity Listing - NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional) NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional) Agency: National Institutes of Health Assistance Listings: 93. 310 -- Trans-NIH Research Support Last Updated: January 20, 2026 View version history on Grants.

gov The National Institutes of Health (NIH) seeks to advance its mission by maintaining strong, productive, and secure international research collaborations in support of the NIH mission. The NIH Collaborative International Research Project (Parent Announcement) supports international research collaborations.

This opportunity specifically implements an award structure of prime domestic awards with independent foreign awards that are linked to the prime. This structure provides NIH with oversight capacity for international collaborations, and allows NIH to track international funding, as identified in... NOT-OD-25-104.

This funding opportunity is specifically designed for NIH to support funded international collaborations between a domestic prime organization and foreign organizations. This NOFO should not be used for foreign consultants, purchasing unique equipment or supplies from foreign vendors, foreign collaborations that do not involve NIH funding or any other foreign component that would not result in a foreign subaward.

All collaborative international research project applications must include at least 1 international subproject. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes, Centers and Offices (ICOs) based on their scientific missions.

The application will be evaluated as a whole, and the international subproject(s) will be evaluated on whether the project presents special opportunities for furthering research programs through the use of unusual talent, resources, populations, or environmental conditions in other countries that are not readily available in the United States or that augment existing United States resources, and whether the proposed project has specific relevance to the mission and objectives of the ICO and has the potential for significantly advancing the health sciences in the United States.

Special district governments Federally recognized Native American tribal governments Public and Indian housing authorities City or township governments Independent school districts Private institutions of higher education Public and state institutions of higher education Other Native American tribal organizations Nonprofits non-higher education without 501(c)(3) Nonprofits non-higher education with 501(c)(3) For-profit organizations other than small businesses Refer to Section III.

Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed. One or more International Project is required. This funding opportunity is specifically designed to support funded international collaborations between a domestic prime organization and foreign organizations.

This NOFO should not be used for projects in which the only international elements are foreign consultants, purchasing unique equipment or supplies from foreign vendors, foreign collaborations that do not involve NIH funding or any other foreign component that would not result in a foreign subaward. Grantor contact information NIH Office of Policy for Extramural Research Administration (OPERA) operasystemspolicy@mail. nih.

gov operasystemspolicy@mail. nih. gov operasystemspolicy@mail.

nih. gov File name Description Last updated PA-26-002-Full-Announcement. html PA-26-002-Full-Announcement.

html Jan 20, 2026 11:36 PM UTC Link to additional information Funding opportunity number : Cost sharing or matching requirement : Funding instrument type : Opportunity Category Explanation : Category of Funding Activity :