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Find similar grantsNIH Director's Pioneer Award (DP1) is sponsored by National Institutes of Health (NIH) Common Fund. This award funds investigators at all career levels to pursue new research and develop groundbreaking, high-impact approaches to biomedical, behavioral, or social science.
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NIH Director's Pioneer Award | NIH Common Fund NIH Director's Pioneer Award NIH Director's Pioneer Award FY2026 NIH Director’s Pioneer Award informational video Part of the High-Risk, High-Reward Research program, the award supports scientists with outstanding records of creativity pursuing new research directions to develop pioneering approaches to major challenges in biomedical, social science, and behavioral research.
Part of the High-Risk, High-Reward Research program , the award supports scientists with outstanding records of creativity pursuing new research directions to develop pioneering approaches to major challenges in biomedical, social science, and behavioral research.
Open to all career stages No preliminary data required Must be new scientific research direction Minimum of 51% research effort in first 3 years 3 Letters of Reference required $700,000 in direct costs per year for up to 5 years See the Award Overview for more information. Applications due September 9, 2026.
Application & Award Guide Recent News & Announcements Nanoscale Explorers: DNA Scouts That Write What They See Exploring Dreams and Memory Scientists Discover Possible Anti-Aging Treatment in Mouse Cells Spotlight on Pioneer Award Recipient's Work to Transform Mental Illness Treatment This page last reviewed on
According to the current listing, eligibility includes: Open to investigators at all career stages. Single Principal Investigator (PI) only. Must be a new research direction and requires at least 51% research effort. Confirm the full requirements in the official notice before applying.
The current listing shows $700,000 per year for 5 years. Verify award ceilings, matching requirements, and allowable costs in the official notice.
NIH Director's Pioneer Award (DP1) is funded by National Institutes of Health (NIH) Common Fund. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
NIH Director's Transformative Research Award for Individual and Group Science (R01 Clinical Trial Optional) (RFA-RM-27-003) is sponsored by National Institutes of Health (NIH) Common Fund. This award supports individual scientists or groups proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new paradigms in infectious biology and beyond.
NIH Director's New Innovator Award (DP2) is sponsored by National Institutes of Health (NIH) Common Fund. The NIH Director's New Innovator Award, part of the High-Risk, High-Reward Research program, supports early-career investigators of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the NIH mission. This award explicitly does not require preliminary data and encourages risky, transformative ideas. Research areas relevant to AI are included.
Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) is sponsored by National Science Foundation (NSF) & National Institutes of Health (NIH). This interagency program supports high-risk, high-reward advances in AI and data science for biomedical and public health research. Projects must cross disciplinary boundaries.
Innovation Grant is a grant from the Delta Dental of Arizona Foundation that funds nonprofit organizations pursuing unique, high-impact projects that improve health and wellness in Arizona communities. This two-year award supports original initiatives with measurable real-world impact, including programs serving underserved and uninsured populations through oral health education, disease prevention, and nutritional access. Projects must demonstrate the potential to make a meaningful difference in the community and stand apart from conventional approaches. Eligible applicants are Arizona-based nonprofit organizations. Awards total $100,000 per recipient over two years. The 2026 application cycle closed October 16, 2025, with recipients notified in late 2025 and funding made available shortly after.
The NIH Common Fund launched PRIMED-AI — Precision Medicine with AI: Integrating Imaging with Multimodal Data — as five coordinated funding opportunities (RFA-RM-27-011 through -015) that build a full pipeline from standards to clinic. Here is how the Playbook, Data-to-Model partnerships, Model-to-Clinic translation, Validation Center, and Logistics Center fit together, what each pays, who is eligible, and how to position before the October 2026 deadlines.
Read articleAvoid common NIH grant proposal mistakes including vague specific aims, weak methodology, and poor budget justification that lead to rejection.
Read articleThe NIH Director's New Innovator Award (DP2, RFA-RM-27-002) closes August 17, 2026, offering roughly 30 Early Stage Investigators up to $475,000 in direct costs a year for five years — $2.375 million total — to pursue bold ideas without the preliminary data a standard R01 demands. Here is how the High-Risk, High-Reward program actually evaluates applications, who qualifies, and why the usual R01 instincts will sink you.
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