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NIH Director's Pioneer Award Program (DP1 Clinical Trial Optional) is sponsored by National Institutes of Health (NIH) Common Fund. This program supports individual scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformativ…
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NIH Director's Pioneer Award | NIH Common Fund NIH Director's Pioneer Award NIH Director's Pioneer Award FY2026 NIH Director’s Pioneer Award informational video Part of the High-Risk, High-Reward Research program, the award supports scientists with outstanding records of creativity pursuing new research directions to develop pioneering approaches to major challenges in biomedical, social science, and behavioral research.
Part of the High-Risk, High-Reward Research program , the award supports scientists with outstanding records of creativity pursuing new research directions to develop pioneering approaches to major challenges in biomedical, social science, and behavioral research.
Open to all career stages No preliminary data required Must be new scientific research direction Minimum of 51% research effort in first 3 years 3 Letters of Reference required $700,000 in direct costs per year for up to 5 years See the Award Overview for more information. Applications due September 9, 2026.
Application & Award Guide Recent News & Announcements Nanoscale Explorers: DNA Scouts That Write What They See Exploring Dreams and Memory Scientists Discover Possible Anti-Aging Treatment in Mouse Cells Spotlight on Pioneer Award Recipient's Work to Transform Mental Illness Treatment This page last reviewed on
According to the current listing, eligibility includes: Individuals from diverse backgrounds and from the full spectrum of eligible institutions in all geographic locations are encouraged to apply. Confirm the full requirements in the official notice before applying.
The published deadline was September 9, 2026, which has passed. Check the official notice for any future application windows before investing time in a proposal.
NIH Director's Pioneer Award Program (DP1 Clinical Trial Optional) is funded by National Institutes of Health (NIH) Common Fund. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
NOT-RM-26-004 asks the public for NIH-wide research challenges worth a 10-year, cross-institute program. There is no budget, no biosketch, no page limit, and no award. What there is: the five criteria every Common Fund investment has met since 2006, a new bullet about small-lab burden, and a fund whose FY 2026 request came in at $347.4 million — down 49.3 percent.
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