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Find similar grantsNIH Exploratory/Developmental Research Grant (Parent R21) is sponsored by National Institutes of Health (NIH). This opportunity supports mission-aligned projects and measurable outcomes.
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Exploratory/Developmental Grants (R21) | Grants & Funding U.S. Department of Health and Human Services National Institutes of Health Exploratory/Developmental Grants (R21) To encourage the development of new research activities in categorical program areas. (Support generally is restricted in level of support and in time.) Application and Submission Information R21 Parent Announcements are available.
Not all NIH institutes and centers participate on all parent announcements. Check the participating organization in the funding opportunity before applying.
Application Characteristics Except when stated otherwise in the funding opportunity: Project period of up to two years Budget for up to $275,000 total in direct costs for the two years, with no more than $200,000 in any year No preliminary data are required, but most opportunities allow it if available Research Strategy may not exceed 6 pages.
The page limit may be different when combined with other activity codes, such as R21/R33 Investigators are strongly encouraged to consult with NIH Scientific/Research staff (see Section VII. Agency Contacts of the funding opportunity) during the concept development stage of the application to determine if an R21 application is appropriate.
After identifying a funding opportunity, follow guidance in the How to Apply – Application Guide instruction call-outs, except where instructed to do otherwise in the funding opportunity or related notices. Exploratory/Developmental Grants Use the Explore NIH Grant Opportunities tool to search Grants. gov. Ready to develop your application?
Learn from a step-by-step guide. Standard Due Dates apply. AIDS and AIDS-Related Applications Beginning with applications for Advisory Council Review in January 2027 (i.e., application due dates on or after May 25, 2026), NIH will no longer accept applications submitted on dedicated AIDS application due dates.
( NOT-OD-26-029 ) Standard Application Due Dates (when applicable) Participating Funding Organizations Each funding opportunity specifies the participating organizations. Applications must fit within the mission of at least one participating funding organization and meet all opportunity-specific requirements. The following funding organizations participate on at least one active funding opportunity.
Division of Program Coordination, Planning and Strategic Initiatives, Office of Disease Prevention Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs Eunice Kennedy Shriver National Institute of Child Health and Human Development Fogarty International Center National Cancer Institute National Center for Advancing Translational Sciences National Center for Complementary and Integrative Health National Heart, Lung, and Blood Institute National Human Genome Research Institute National Institute of Allergy and Infectious Diseases National Institute of Arthritis and Musculoskeletal and Skin Diseases National Institute of Biomedical Imaging and Bioengineering National Institute of Dental and Craniofacial Research National Institute of Diabetes and Digestive and Kidney Diseases National Institute of Environmental Health Sciences National Institute of General Medical Sciences National Institute of Mental Health National Institute of Neurological Disorders and Stroke National Institute of Nursing Research National Institute on Aging National Institute on Alcohol Abuse and Alcoholism National Institute on Deafness and Other Communication Disorders National Institute on Drug Abuse National Institute on Minority Health and Health Disparities National Library of Medicine Office of Behavioral and Social Sciences Research Office of Research on Women's Health Tribal Health Research Office Your organization's sponsored programs office or grants administrators can answer many internal and agency policy and process questions.
Understand NIH Staff Roles details how and when to find the right NIH contacts: Before you apply, check your chosen funding opportunity for application submission, scientific/research, peer review, and financial/grants management contacts. After you apply, find NIH staff assignments in the Status module of eRA Commons . For technical issues E-mail OER Webmaster
Based on current listing details, eligibility includes: Nonprofits, Universities, State/local governments, For-profit organizations, Small businesses, Individuals Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates Up to $275,000 over 2 years Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is rolling deadlines or periodic funding windows. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
Yes — AI tools like Granted can help research funders, draft proposal sections, and check compliance. However, always review and customize AI-generated content to reflect your organization's unique strengths and the specific requirements of the solicitation.
Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.
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Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs (NIH) is sponsored by National Institutes of Health (NIH). The NIH SBIR/STTR programs offer non-dilutive funding for early-stage research and development in life sciences. The National Institute on Minority Health and Health Disparities (NIMHD) specifically encourages entrepreneurs from all backgrounds with product ideas and concepts whose potential commercialization supports the NIH research mission to apply. This could include manufacturing aspects of biomedical innovations.
NIH NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00) is a grant from the National Institutes of Health (NIH) / National Cancer Institute (NCI) that funds early-stage postdoctoral researchers in cancer-related fields to transition to independent research careers. The award provides a mentored phase (K99) followed by an independent phase (R00), supporting investigators who do not require an extended period of supervised training beyond their doctoral degrees. Eligible applicants must hold a research or clinical doctoral degree and be postdoctoral fellows who have not yet established independent research careers. The March 11, 2026 due date applies; award amounts vary by project.
NIH R25 Summer Research Education Experience Program is a grant from the National Institutes of Health (NIH) that funds universities and institutions of higher education to provide summer research experiences in environmental health sciences to high school students, college undergraduates, and science teachers. Administered through the National Institute of Environmental Health Sciences (NIEHS), the program aims to attract young people to scientific careers and help teachers communicate about the scientific process more effectively. Eligible applicants are U.S. institutions eligible for NIH grants. The application deadline was March 17, 2026.
-Purpose. This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to develop, standardize, and validate new and innovative assays, integrated strategies, or batteries of assays that determine or predict specific organ toxicities (e.g., ocular, dermal, hematotoxicity, cardiotoxicity, gastrointestinal toxicity, hepatotoxicity, nephrotoxicity, ototoxicity, olfactory loss, bladder toxicity, neurotoxicity, pulmonary toxicity, endocrine toxicity, and pancreatic beta cell toxicity), resulting from both acute and chronic exposures to various chemicals, environmental pollutants, biologics and therapeutic molecules or drugs. In addition, this FOA encourages the development, standardization, and validation of new models of arthritis, convulsion, infection and shock. New approaches for high throughput toxicity screening that involves the use of molecular endpoints, computer modeling, proteomics, genomics and epigenomics and the development of virtual tissues are also encouraged as are development of 3-dimensional organ models for toxicity evaluation. -Mechanism of Support. This FOA will utilize the SBIR (R43/R44) grant mechanisms for Phase I, Phase II, and Fast-Track applications and runs in parallel with a FOA of identical scientific scope, PA-09-007, which encourages applications under the Small Business Technology Transfer (STTR) (R41/R42) grant mechanisms. Funding Opportunity Number: PA-09-006. Assistance Listing: 93.113,93.173,93.361,93.389,93.837,93.846,93.847,93.848,93.849,93.859,93.867. Funding Instrument: G. Category: ED,ENV,FN,HL.
Purpose. This Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI), National Institutes of Health (NIH), invites Small Business Innovation Research (SBIR) cooperative agreement applications from small business concerns (SBCs) that propose to develop new, or to improve existing application(s) of nanotechnology-based therapeutics or/and in vivo diagnostics. This FOA will specifically support pre-clinical optimization and testing of these cancer-relevant nanotechnology applications against the intended cancer type. The proposed projects must be milestone-driven and must be clearly directed toward development of an ultimate commercial product. The outcomes are expected to advance the discovery and pre-clinical optimization phase so that an Investigational New Drug (IND) or Investigational Device Exemptions (IDE) application could be submitted to the Food and Drug Administration (FDA) by the end or shortly after completion of the Phase II project period. To facilitate these steps, the NCI will assist the awardees in various ways, including the support through the NCI-sponsored Nanotechnology Characterization Laboratory. This FOA will NOT support basic research projects, studies on disease mechanisms, and clinical trials. Mechanism of Support. This FOA will utilize the SBIR (U43/U44) cooperative agreement mechanisms for Phase I and Phase II applications. Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. The total amount awarded and the number of awards will depend upon the quality, duration, and costs of the applications received. Funding Opportunity Number: PAR-10-286. Assistance Listing: 93.393,93.394,93.395,93.396. Funding Instrument: CA. Category: ED,HL. Award Amount: Up to $150K per award.
This Funding Opportunity Announcement (FOA) invites Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) for funding to perform research leading to the development of innovative technologies that may advance progress for early detection and assessment of individuals at risk and for early diagnosis, prognosis and follow-up of type 1 diabetes (T1D). Funding Opportunity Number: RFA-DK-15-024. Assistance Listing: 93.847. Funding Instrument: G. Category: FN,HL. Award Amount: $2M total program funding.