NIH Glycoscience Center of Research Excellence (GlyCORE) Funding

NIH Glycoscience Center of Research Excellence (GlyCORE) Funding is sponsored by National Institutes of Health (NIH). This renewed grant funds glycoscience research at the University of Mississippi's Glycoscience Center of Research Excellence (GlyCORE).

GlyCORE: Glycoscience Center of Research Excellence Project Number 5P20GM130460-03 Contact PI/Project Leader SHARP, JOSHUA S Project Summary/Abstract The University of Mississippi proposes to establish the Glycoscience Center of Research Excellence (GlyCORE), a Phase I Center of Biomedical Research Excellence.

Glycoscience is an essential and rapidly emerging field of biomedical science, and the challenging nature of glycoscience research requires tools and expertise that are not commonly found in the biomedical research community.

Moreover, the biomedical community is rapidly growing to appreciate the essential role of carbohydrates, with researchers outside of the self-identified “glycoscience” community finding themselves faced with addressing challenging questions in glycoscience as part of the course of their biomedical researchers.

GlyCORE will develop and provide resources and expertise in glycoscience to both core glycoscience researchers as well as researchers who encounter questions in glycoscience in the course of their biomedical research programs.

GlyCORE will serve researchers at both the University of Mississippi and the Mid-South community through three mechanisms: a Faculty Development program, the establishment of three Research Cores to support glycoscience research, and the establishment of local and regional meetings focusing on questions in glycoscience.

GlyCORE's Faculty Development program includes the support of four Junior Investigators establishing their careers in various disciplines in glycoscience. This program includes financial support of the investigators' research efforts, a formal mentoring program, and priority subsidized access to University of Mississippi core facilities.

GlyCORE will also support smaller developmental projects through a Pilot Project Program, including financial support and prioritized access to core facilities. GlyCORE's Faculty Development program will also promote recruitment of glycoscience faculty to the University of Mississippi, including the recruitment of a mid-career carbohydrate synthetic chemist to help support expanded services in GlyCORE during Phase II.

GlyCORE's Research Cores will establish three new core capabilities at the University of Mississippi that are essential for modern glycoscience: an Analytical and Biophysical Core supporting high resolution chromatography and mass spectrometry analyses; an Imaging Core supporting confocal microscopy with lectin-based and anti- carbohydrate immunohistochemistry imaging; and a Computational and Bioinformatics Core supporting simulations and bioinformatics data analysis to support glycoscience and structural glycobiology.

Finally, GlyCORE will establish the University of Mississippi as a regional center for glycoscience in the Mid-South. GlyCORE will host an annual Mid-South Glycoscience Meeting with subsidized access to regional participants, and will host both an annual UM Glycoscience Symposium and monthly glycoscience meetings to highlight the role of glycoscience at the University of Mississippi.

Together, these efforts will establish a core of experienced and nationally competitive young faculty in glycoscience, supported by modern research infrastructure and promoted to the glycoscience community as the glycoscience destination in the Mid-South.

Public Health Relevance Statement Project Narrative The University of Mississippi proposes to establish the Glycoscience Center of Research Excellence (GlyCORE), a new University-wide center to study how carbohydrates and carbohydrate-containing molecules affect human health.

GlyCORE will support investigators in glycoscience through direct funding of selected research projects, establish mentors for early career investigators, support the recruitment of new faculty in glycoscience, and develop local and regional meetings for investigators to discuss their work.

GlyCORE will also support the establishment of three central research cores to support these investigators with cutting-edge biomedical research tools. No NIH Spending Category available.

Address Affect Alabama Area Arkansas Biochemistry and Cellular Biology Bioinformatics Biological Biomedical Research Biophysics Carbohydrates Cell Communication Cells Centers of Research Excellence Chemicals Chemistry Chromatography Communities Confocal Microscopy Core Facility Data Analyses Destinations Development Discipline Energy Metabolism Faculty Faculty Recruitment Financial Support Funding Future Glycobiology Glycosides Health Human Image Immunohistochemistry In Vitro International Kentucky Lectin Louisiana Mass Spectrum Analysis Mentors Mentorship Mississippi Missouri Modernization NMR Spectroscopy Natural Products Nature Neurosciences Research Participant Pharmacologic Substance Pharmacology Phase Physiological Pilot Projects Play Polysaccharides Program Development Protein-Carbohydrate Interaction Proteins Publishing Recording of previous events Regulation Research Research Infrastructure Research Personnel Research Project Grants Research Support Resolution Resources Role Science Services Teacher Professional Development Tennessee United States National Academy of Sciences United States National Institutes of Health Universities Work base biological systems career computational chemistry experience faculty support glycation human disease improved in vivo innovation instrumentation interest meetings member programs recruit response simulation symposium tool tool development Administering Institutes or Centers National Institute of General Medical Sciences Assistance Listing Number Project Funding Information for 2022 No Sub Projects information available for 5P20GM130460-03 Publications are associated with projects, but cannot be identified with any particular year of the project or fiscal year of funding.

This is due to the continuous and cumulative nature of knowledge generation across the life of a project and the sometimes long and variable publishing timeline. Similarly, for multi-component projects, publications are associated with the parent core project and not with individual sub-projects.

No Publications available for 5P20GM130460-03 No Patents information available for 5P20GM130460-03 The Project Outcomes shown here are displayed verbatim as submitted by the Principal Investigator (PI) for this award. Any opinions, findings, and conclusions or recommendations expressed are those of the PI and do not necessarily reflect the views of the National Institutes of Health. NIH has not endorsed the content below.

No Outcomes available for 5P20GM130460-03 No Clinical Studies information available for 5P20GM130460-03 No news release information available for 5P20GM130460-03 No Historical information available for 5P20GM130460-03 No Similar Projects information available for 5P20GM130460-03 ## Select options for export: