NIH National Center for Complementary and Integrative Health (active funding announcements)

NIH National Center for Complementary and Integrative Health (active funding announcements) is sponsored by National Center for Complementary and Integrative Health (NCCIH). NCCIH funds and conducts research to answer scientific and public health questions about complementary health approaches.

National Center for Complementary and Integrative Health (NCCIH) | Grants & Funding U.S. Department of Health and Human Services National Institutes of Health National Center for Complementary and Integrative Health (NCCIH) NCCIH Policy Considerations Additional Information by Funding Category The NCCIH Mission is to determine, through rigorous scientific investigation, the fundamental science, usefulness, and safety of complementary and integrative health approaches and their roles in improving health and health care.

Geneal Research topics of interest include: Examining how biological, behavioral, psychological, social, and environmental factors interact to influence health, resilience, and recovery. Studying complementary and integrative health interventions including multicomponent interventions targeting multisystem outcomes for disease treatment and prevention, and for health restoration and promotion.

Using AI and multiscale modeling to understand whole person health dynamics. Fundamental Science and Translational Research Probing neural, biological, biomechanical, physiological and behavioral mechanisms underlying complementary and integrative health approaches. Advancing translational research to inform intervention development and optimization.

Clinical Research and Implementation: Supporting feasibility studies, rigorous explanatory clinical trials, pragmatic studies to evaluate effectiveness, safety, and real-world applicability, Improving uptake of evidence-based integrative approaches into clinical care, public health, and self-care.

Advancing evidence on integrative, non-drug strategies (e.g., mind–body, manual therapies, movement-based approaches) for acute and chronic pain. Studying mechanisms, effectiveness, and implementation of practices. Refining mind and body interventions to treat and prevent disease and promote health.

Health Promotion and Disease Prevention Studying integrative approaches and their mechanisms that support healthy behaviors, resilience, prevent disease, and promote well-being across the lifespan.

Nutrition & Natural Products Studying effects of natural products, phytochemicals, and probiotics on health and disease including inter-individual differences Investigating the mechanisms and potential therapeutic effects of cannabis and minor cannabinoids. Highlighted Topics identify timely or emerging research priorities across one or more NIH Institutes, Centers, or Offices (ICOs).

Use Parent Announcements or other broad NIH opportunities to submit investigator-initiated applications on a topic. While Highlighted Topics do not affect referral or review, some include dedicated funding. See the Highlighted Topic FAQs NCCIH Grant Funding Opportunity Notices in the NIH Guide for Grants and Contracts NCCIH Policy Considerations All NIH ICOs follow a set of NIH-wide policies .

These ICO-specific considerations build on those policies. NCCIH General Funding Policies Additional Information by Funding Category Administrative Supplements In addition to our Administrative Supplements overview, consider the following NCCIH-specific information.

Administrative Supplement Interest Areas: NCCIH has prioritized funding investigator-initiated grants at the highest possible level, so the number of successful administrative supplement applications will be low. Investigators are strongly encouraged to contact their NCCIH Program Officer before submission to confirm eligibility and ensure alignment with NCCIH scientific priorities.

Administrative Supplement Due Dates: Requests are reviewed on a rolling basis. Investigators should apply well in advance of the desired start date. Administrative Supplement Contact: Contact the program officer listed on the Notice of Award for the most recent parent award.

Direct general questions to: [email protected] In addition to our Conferences and Meetings overview, consider the following NCCIH-specific information. Conferences and Meetings Interest Areas: NCCIH Will Support Meetings or Conferences that: Advance innovative, rigorous, and high-quality research on complementary and integrative health (CIH).

Focus on basic, mechanistic, translational, clinical, or implementation research relevant to NCCIH. Identify research gaps, methodological challenges, and future directions for CIH research. Foster interdisciplinary collaboration (e.g., biology, neuroscience, behavioral science, clinical research, research training, and capacity building) in CIH research.

Align with NCCIH strategic priorities (e.g., pain, symptom management, or whole person health). NCCIH Generally Will Not Support Meetings or Conferences Workshops that: Focus primarily on certification, professional training, or continuing education without a strong research component. Promote or advocate commercial interest in specific therapies or products.

Center on non-research policy, lobbying, or business. CIH research is peripheral rather than central to the agenda. Conferences and Meetings Budget Considerations: Up to $30K/year : support can vary depending on rationale, justification, and relevance of the conference to NCCIH’s mission and priorities.

Priority use: travel awards for trainees/early-career investigators and CIH researchers, mentoring activities, virtual access, modest support for wellness programming. Will not fund salaries, room rental, A/V equipment fees, publications, or speaker fees. Conferences and Meetings Key Date Considerations: NCCIH does not restrict conference support to specific receipt cycles.

Applications should use NIH standard submission, review, and Council cycles . Funding decisions are based on programmatic relevance, priority, and availability of funds. Conferences and Meetings Project Period Considerations: NCCIH may consider support for single scientific meetings under the R13/U13 mechanism.

Support for recurring meetings is considered only for major flagship conferences, with funding evaluated each year based on relevance to NCCIH priorities, scientific merit, and available funds. Conferences and Meetings Contacts: Division of Extramural Research and Training Individual Career Development In addition to our Individual Career Development , consider the following NCCIH-specific information.

Individual Career Development Interest Areas: NCCIH participates in individual career development awards for supervised research leading to independence and midcareer awards to support mentorship in patient-oriented research with high relevance to the NCCIH mission, including Research Scientist Development Award (K01) Clinical Investigator Award (K08) Mentored Patient-Oriented Research Career Development Award (K23) Midcareer Investigator Award in Patient-Oriented Research (K24) Candidates with least one active, independent, peer-reviewed R01 or R01-like grant award are prioritized.

Career Transition Award (K99) NCCIH supports supervised research across the lifespan, spanning basic/mechanistic and translational studies to observational, clinical, and implementation research. NCCIH does not support early career awards proposing clinical trials to test efficacy or effectiveness.

Priority research areas include (but are not limited to): Complementary and integrative health approaches on whole person health, health restoration, and symptom management. Fundamental, mechanistic, and translational studies of complementary and integrative health approaches. Studies to optimize approaches for prevention or management of chronic conditions and to promote health.

Contextual factors influencing implementation and uptake of these approaches. Priority training areas include (but are not limited to): Complementary and integrative health-relevant basic/mechanistic, translational, clinical, and dissemination and implementation research. The intersection of these approaches with whole person health, pain, interoception, emotional well-being, resilience, health promotion, and disease prevention.

Novel methods, delivery modalities, and innovative technologies (e.g., AI, machine learning, metabolomics, cheminformatics, systems pharmacology, microbiome multi-omics). NCCIH encourages individuals with clinical training (e.g., MD, DO, DC, ND, DAOM, DPT, clinical psychology) to apply.

Individual Career Development Salary Fringe Benefits: K01: up to $75,000/year + fringe K08, K23: up to $100,000/year + fringe K99: Commensurate with the institutional salary structure for persons of equivalent qualifications, experience, and rank. K24: up to the maximum legislative salary cap/year + fringe In all cases, salary must align with institutional base salary for equivalent qualifications and will be verified at award.

Individual Career Development Other Program Related Expenses: NCCIH sets the following research support expectations per year: K01, K08, K23: up to $25,000 Allowable costs may include research supplies, technical support, and training activities that directly support career development. Requests should be well justified and aligned with the proposed research and training plan.

Individual Career Development Research Effort Considerations: Applicants should ensure sufficient protected time to conduct proposed research and career development activities. K24 applicants should commit 20-50% effort. K24 renewal applications are expected to commit 20-30% effort.

Individual Career Development Contacts: NCCIH Division of Extramural Research (DER) In addition to our Individual Fellowships Overview, consider the following NCCIH-specific information. Individual Fellowships Interest Areas: NCCIH participates in the NSRA Predoctoral and Postdoctoral Fellowships and the Predoctoral to Postdoctoral Transition Award.

For NCCIH applications that include, but are not limited to the following are encouraged: Individuals and clinician-scientists (e.g., physicians, complementary health practitioners, and other professionals) pursuing careers in complementary and integrative health research. Training that strengthens rigor, reproducibility, and innovation in complementary and integrative health research.

Training in translational science, pragmatic clinical trials, and dissemination and implementation research to support the integration of complementary and integrative health approaches into health care and community settings. Basic/mechanistic, translational and clinical research investigating complementary and integrative health approaches relevant to NCCIH’s mission.

NCCIH does not participate in the NRSA for Senior Fellows supporting an expansion or change in career (F33). Individual Fellowships Budget Considerations: Current NRSA stipends, tuition/fees, and budgetary levels apply.

Individual Fellowships Contacts: Division of Extramural Research and Training Institutional Career Development and Other Training In addition to our Institutional Career Development and Other Training , consider the following NCCIH-specific information. Institutional Career Development and Other Training Interest Areas: NCCIH does not participate in any Institutional Career development programs.

In addition to our Institutional Training , consider the following NCCIH-specific information. Institutional Training Interest Areas: NCCIH participates in institutional training programs that support long- (T32) and short-term (T35) mentored research experiences in complementary and integrative health for predoctoral and postdoctoral trainees.

NCCIH encourages institutions with research-intensive environments, institutions focused on complementary health practice, and other eligible organizations that have the research expertise, curriculum, infrastructure, and faculty to apply. Programs that include complementary health practitioners (e.g., chiropractors, acupuncturists, naturopaths) and clinicians as trainees or key contributors are encouraged.

NCCIH supports supervised research across the lifespan, spanning from basic/mechanistic and translational studies to observational, clinical, and implementation research. Priority research areas include (but are not limited to): Complementary and integrative health approaches on whole person health, health restoration, and symptom management.

Fundamental, mechanistic, and translational studies of complementary and integrative health approaches. Studies to optimize approaches for prevention or management of chronic conditions and to promote health. Contextual factors influencing implementation and uptake of these approaches.

Priority training areas include (but are not limited to): Training in complementary and integrative health-relevant basic/mechanistic, translational, clinical, and dissemination and implementation research. Training in the intersection of these approaches with whole person health, pain, interoception, emotional well-being, resilience, health promotion, and disease prevention.

Training in novel methods, delivery modalities, and innovative technologies (e.g., AI, machine learning, metabolomics, cheminformatics, systems pharmacology, microbiome multi-omics). NCCIH prioritizes programs that do not substantially overlap with existing NCCIH-funded institutional training programs.

Institutional Training Participants: NCCIH prioritizes funding for the following trainees: NCCIH prioritizes funding for the following trainees: predoctoral, postdoctoral, short-term trainees, and individuals with clinical training (e.g., MD, DO, DC, ND, DAOM, DPT, clinical psychology) interested in complementary and integrative health-relevant research careers.

Institutional Training Key Date Considerations: Although new , renewal , and resubmission applications are accepted for all opportunity due dates, funding decisions for new applications are only made after October council. We recommend submitting new applications to due dates that align with October Council for the shortest time from application to award.

Institutional Training Budget Considerations: Awards will be made for a maximum of 4 trainee slots per year, with an exception for up to 5 slots if the additional slot is reserved for supporting a complementary and integrative health practitioner.

NCCIH supports travel costs for travel to relevant scientific meetings and other training activities: T32 trainees up to $2,000 per trainee per year and T35 trainees up to $1,000 per trainee per year. Institutional Training Contacts: National Center for Complementary and Integrative Health (NCCIH) Division of Extramural Research (DER) In addition to our Research Projects , overview, consider the following NCCIH-specific information.

Research Projects Contacts: Division of Extramural Research Branch In addition to our Small Business overview, consider the following NCCIH-specific information. Small Business Interest Areas: The NCCIH will support applications on the development of technologies and therapies relevant to complementary and integrative approaches.

Complementary health approaches include a broad range of practices and interventions that can be classified by their primary therapeutic input, including nutritional and natural products (e.g., special diets, dietary supplements, botanicals, probiotics, and microbial-based therapies), psychological (e.g., meditation, hypnosis, music-based interventions, relaxation therapies), physical (e.g., acupuncture, massage, chiropractic manipulation, other force-based manipulations, or devices related to these approaches), or a combination of psychological and physical (e.g., yoga, tai chi, or some forms of art therapies, such as music-based interventions) input.

Additionally, NCCIH will support applications that explore the impact of complementary and integrative health approaches on health promotion, resilience, and whole person health.

Overall, NCCIH will support applications that include complementary and integrative health approaches, including multicomponent interventions that combine two or more complementary and integrative health approaches, or one or more complementary approaches integrated with one or more conventional care interventions.

Approved Topics for Awards Over Statutory Budget Guidelines: Novel technologies/methods to study the mechanistic effects of complementary and integrative health (CIH) Research to enhance the safety, scalability, reproducibility, and translatability of CIH interventions Innovative methods and technologies to evaluate evidence-based CIH approaches Studies to optimize the impact of natural product(s) on target engagement(s) Development of diagnostic and prognostic technologies to support CIH interventions Technologies to integrate CIH approaches into healthcare delivery Phase IIB & Commercialization Readiness Pilot (CRP): NCCIH does not accept Phase IIB SBIR projects NCCIH does not accept Commercialization Readiness Pilot (CRP) projects NCCIH accepts clinical trials through the SBIR programs NCCIH accepts clinical trials through the STTR programs NCCIH does not accept clinical trials through the Phase IIB SBIR program NCCIH does not accept clinical trials through the Commercialization Readiness Pilot (CRP) Name: NCCIH DER Funding Questions National Center for Complementary and Integrative Health (NCCIH) Just getting started and want to discuss your research idea?

Use Matchmaker to find relevant NIH program officials. Enter your draft specific aims, abstract, or other scientific text and choose the "Similar Program Officials" option. The search results list matching funding ICOs and NIH program officials.

Reach out to best match first, and don't worry if it's not a perfect fit. They can direct you to who is. Learn more in the Matchmaker Tool Video Tutorial .

Already applied or received an award? Reach out to the contacts listed in the Status section of eRA Commons for your application or award. Still not sure who to talk to?

Use the email addresses listed in each of the funding category sections above. For technical issues E-mail OER Webmaster