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NCATS program (PAR-25-157) supporting development of innovative technologies for translational science including AI/ML-driven drug discovery, high-throughput screening automation, computational target identification, and novel assay platforms. Funds exploratory research that creates new tools, methods, and technologies to overcome specific translational bottlenecks in the drug development pipeline.
Part of NCATS' broader mission that has enabled over 45 promising new drugs to move into clinical trials through partnerships with academia, industry, and patient advocacy groups. NCATS maintains a pharmaceutical collection of nearly every human-approved drug and automated solutions for rapid drug repurposing screening including for emerging infectious diseases.
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Or search similar grants →According to the current listing, eligibility includes: US academic institutions, nonprofit organizations, small businesses, and for-profit organizations. Clinical trials not allowed under this R21 award mechanism. Foreign components may be allowed with appropriate justification. Confirm the full requirements in the official notice before applying.
The current listing shows R21 exploratory/developmental research grants. Up to $275,000 in direct costs over 2 years. Budget for initial year generally limited to $200,000. Verify award ceilings, matching requirements, and allowable costs in the official notice.
The published deadline was June 18, 2026, which has passed. Check the official notice for any future application windows before investing time in a proposal.
NIH NCATS Awards Supporting Cutting-Edge Technologies for Translational Science (ASCETTS) for AI-Enabled Drug Discovery is funded by National Center for Advancing Translational Sciences (NCATS/NIH). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed) is sponsored by National Center for Advancing Translational Sciences (NCATS/NIH). This R03 grant supports pilot projects focused on investigating understudied proteins that are associated with rare diseases. The goal is to generate preliminary data for future research. Clinical trials are not allowed.
Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional) is sponsored by National Center for Advancing Translational Sciences (NCATS/NIH). This limited competition R03 grant program is specifically designed to enhance the research capabilities of NCATS CTSA Program KL2 scholars and recipients of re-entry supplements.
The Department of Defense FY2026 Defense University Research Instrumentation Program (DURIP) provides funding for U.S. universities to acquire research equipment and instrumentation in areas important to national defense, including AI and machine learning hardware. The program is administered jointly by the Army Research Office (ARO), Office of Naval Research (ONR), and Air Force Office of Scientific Research (AFOSR), with approximately $34 million available and 95 awards anticipated. DURIP funds the acquisition of specialized computing hardware for AI/ML research (GPU clusters, TPUs, neuromorphic processors), robotics and autonomous systems testbeds, sensor arrays and data collection systems for machine learning training, high-performance computing infrastructure for defense-relevant AI research, and laboratory equipment for human-AI interaction studies. The program specifically supports equipment that enhances research-related education in DoD-priority disciplines. While general-purpose computing is not eligible, computing equipment directly supporting DoD-relevant AI research programs qualifies. No cost sharing is required.
Vinnova, Sweden's national innovation agency, funds projects developing applied AI solutions for Swedish industry through its Advanced Digitalization Programme. Each project can apply for between 2 and 10 million SEK (approximately $190,000 to $950,000 USD) covering up to 50% of eligible project costs. The total call budget is 60 million SEK. Projects run for 12-24 months and focus on two key areas: Intelligent Edge (AI for real-time application in the sensor chain) and AI-based decision support. All projects must address industrial needs and integrate gender equality and climate change perspectives. Scientific publications must be open access. A parallel call also funds AI and cybersecurity projects at 1-10 million SEK per project with a 50 million SEK total budget.
Advance from NIH SBIR Phase I to Phase II with tips on demonstrating feasibility, building a commercialization plan, and securing $1M in funding.
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