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NCATS program (PAR-25-157) supporting development of innovative technologies for translational science including AI/ML-driven drug discovery, high-throughput screening automation, computational target identification, and novel assay platforms. Funds exploratory research that creates new tools, methods, and technologies to overcome specific translational bottlenecks in the drug development pipeline.
Part of NCATS' broader mission that has enabled over 45 promising new drugs to move into clinical trials through partnerships with academia, industry, and patient advocacy groups. NCATS maintains a pharmaceutical collection of nearly every human-approved drug and automated solutions for rapid drug repurposing screening including for emerging infectious diseases.
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Search similar grants →Based on current listing details, eligibility includes: US academic institutions, nonprofit organizations, small businesses, and for-profit organizations. Clinical trials not allowed under this R21 award mechanism. Foreign components may be allowed with appropriate justification. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates R21 exploratory/developmental research grants. Up to $275,000 in direct costs over 2 years. Budget for initial year generally limited to $200,000. Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is June 18, 2026. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
Yes — AI tools like Granted can help research funders, draft proposal sections, and check compliance. However, always review and customize AI-generated content to reflect your organization's unique strengths and the specific requirements of the solicitation.
Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.
The Department of Defense FY2026 Defense University Research Instrumentation Program (DURIP) provides funding for U.S. universities to acquire research equipment and instrumentation in areas important to national defense, including AI and machine learning hardware. The program is administered jointly by the Army Research Office (ARO), Office of Naval Research (ONR), and Air Force Office of Scientific Research (AFOSR), with approximately $34 million available and 95 awards anticipated. DURIP funds the acquisition of specialized computing hardware for AI/ML research (GPU clusters, TPUs, neuromorphic processors), robotics and autonomous systems testbeds, sensor arrays and data collection systems for machine learning training, high-performance computing infrastructure for defense-relevant AI research, and laboratory equipment for human-AI interaction studies. The program specifically supports equipment that enhances research-related education in DoD-priority disciplines. While general-purpose computing is not eligible, computing equipment directly supporting DoD-relevant AI research programs qualifies. No cost sharing is required.
Sustainable Transportation Planning Grants is sponsored by California Department of Transportation (Caltrans). This program supports Caltrans' mission to improve lives and communities by funding projects that promote sustainable, safe, and accessible transportation across California. It includes Sustainable Communities Grants, which encourage local/regional planning supporting state goals and greenhouse gas reduction targets, and Strategic Partnerships Grants, which address statewide, interregional, or regional transportation deficiencies on the State Highway System in partnership with Caltrans.