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"NIH Research Project Grant (Parent R01 Clinical Trial Optional)" is currently closed and not accepting applications.
Supports health-related research and development based on the mission of the NIH.
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Or search similar grants →Key questions and narrative sections extracted from the solicitation.
Specific Aims
Research Strategy
Data Management and Sharing Plan
Scoring criteria used to review proposals for this grant.
According to the current listing, eligibility includes: Nonprofits, Universities, State/local governments. Confirm the full requirements in the official notice before applying.
The published deadline was May 24, 2026, which has passed. Check the official notice for any future application windows before investing time in a proposal.
NIH Research Project Grant (Parent R01 Clinical Trial Optional) is funded by National Institutes of Health. Verify program details on the funder's official page before applying.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
The solicitation lists 6 required documents: SF424(R&R), Budget forms, PHS 398 Research Plan, Resource Sharing Plan, Data Management Plan, and Senior/Key Person Profile. Check the official notice for formatting and page-limit rules.
Past winners and funding trends for this program
PA-27-037 consolidates the Predoctoral to Postdoctoral Transition Award into a single parent announcement across 20 NIH components, with the next deadline December 8, 2026. The eligibility gate is not the science — it is a mandatory change of institution and mentor between the F99 and K00 phases.
Read articleA draft executive order would have put OMB Director Russell Vought on a commission with final say over NIH awards after peer review. Sen. Collins killed it by pointing at a provision Congress already passed. Here is what the episode teaches applicants about the December 11 cliff.
Read articlePA-27-034, PA-27-035 and PA-27-036 replace the institute-specific R25 announcements that research education programs have been built around for a decade. NCI, NIDA and NIGMS have already expired theirs early. Here is what the consolidation actually changes: an 8% indirect cost ceiling, a US-citizens-and-permanent-residents participant rule, a cooperative agreement variant that only exists on one of the three, and no clinical-trial-allowed companion anywhere.
Read article