NINDS Research Education Grant (R25) Programs for Residents and Fellows in Neurology, Neurosurgery, Neuropathology, and Neuroradiology

NINDS Research Education Grant (R25) Programs for Residents and Fellows in Neurology, Neurosurgery, Neuropathology, and Neuroradiology is sponsored by National Institute of Neurological Disorders and Stroke (NINDS). This opportunity supports mission-aligned projects and measurable outcomes.

NINDS Research Education Programs for Residents and Fellows in Neurology, Neurosurgery, Neuropathology, Neuroradiology and Emergency Medicine (R25) - Scott Josephson NINDS Research Education Programs for Residents and Fellows in Neurology, Neurosurgery, Neuropathology, Neuroradiology and Emergency Medicine (R25) University of California San Francisco, San Francisco, CA, United States Search grants from University of California San Francisco Genetic Etiology of Bicuspid Aortic Valve Disease Modulation of skin cancer by PPARBeta/delta Tso-Tsi-Ge-Yu-Hi Di-Ni-Yo-Tli """"""""We Care Deeply for the Children Kentucky Mental Health Statistics Improvment Project Remote-Sterilizing Coatings Using Magnetic Nanoparticles The HIV Latent Reservoir, Suboptimal Immune Response on Antiretroviral Therapy, and Exogenous Cytokine Therapies Mechanisms of inv(16) acute myeloid leukemia Natural killer cell regulation of the germinal center HIV neutralizing antibody response Engineering Nanomaterials to Prime Immunity A value affirmation intervention for physical symptoms and medication adherence in breast cancer patients taking aromatase inhibitors The Department of Neurology at UCSF has been the institutional sponsor for the R25 program at UCSF over the past 10 years and is the home department for this application renewal.

Neurology, Neurosurgery, and Neuropathology have supported outstanding research training candidates through this program. The Department of Neurology has an excellent record for attracting outstanding medical students destined for neurology. Out of 280 applications from US medical graduates for 10 adult neurology positions in 2018, we were fortunate to match all 10 positions to the top seventeen applicants on our rank list.

The department aspires to train the next generation of national neurology leaders, and our neurology residency graduates transition in high numbers to long-term academic careers as laboratory investigators, clinical science (patient- based) investigators, and university-based clinician teachers.

The opening of the Sandler Neurology Research Building at the Mission Bay campus (see facilities below) in 2012 has resulted in greatly expanded opportunities for research trainees and collaboration between laboratory research programs in a common space and with nearby research programs (e.g., Gladstone Institute, VA Laboratories at Mission Bay). The intellectual environment is productive and exciting for trainees.

Monthly multidisciplinary conferences (e.g., Brain Club and Grand Rounds) host speakers who discuss translational science issues that attract both clinicians and bench scientists, many of these programs are specifically directed at the level of the trainee. These conferences are followed often by an opportunity to informally mix with colleagues who have diverse clinical and scientific interests.

The R25 has been a crucial linchpin for the development of research skills by our talented young physician- scientists in neurology, neurosurgery, and neuropathology at UCSF. In an era of increased competition for limited resources, the R25 has become a reliable source of encouragement as well as a stable NIH program for ensuring that our most talented early career neuroscientists are well-supported and well-mentored.

The burden of increasing numbers of older adults in the United States continues to add to the societal burden of neurologic disease, but current treatments and prevention strategies are ineffective for many of these disorders.

By supporting early translational research training and experiences for young physician-scientists, the R25 research education and research program continues to be an important mechanism for stoking the pipeline for physician-neuroscientists who will make important translational research discoveries that improve the future prevention and treatment of nervous system diseases.

The translational neuroscience community at UCSF is positioned to expand the outstanding environment for the R25 program by virtue of our commitment to training physician-scientists, demonstrated track record of success, existing and anticipated future new facilities, and the research accomplishments of our faculty.

Agency National Institute of Health (NIH) Institute National Institute of Neurological Disorders and Stroke (NINDS) Type Education Projects (R25) Project # 2R25NS070680-11 Study Section Special Emphasis Panel (ZNS1) Program Officer Korn, Stephen J Name University of California San Francisco Wang, Doris D; de Hemptinne, Coralie; Miocinovic, Svjetlana et al.

(2018) Pallidal Deep-Brain Stimulation Disrupts Pallidal Beta Oscillations and Coherence with Primary Motor Cortex in Parkinson's Disease. J Neurosci 38:4556-4568 Orengo, James P; van der Heijden, Meike E; Hao, Shuang et al. (2018) Motor neuron degeneration correlates with respiratory dysfunction in SCA1.

Dis Model Mech 11: Baud, Maxime O; Kleen, Jonathan K; Anumanchipalli, Gopala K et al. (2018) Unsupervised Learning of Spatiotemporal Interictal Discharges in Focal Epilepsy. Neurosurgery 83:683-691 Raju, Chandrasekhar S; Spatazza, Julien; Stanco, Amelia et al.

(2018) Secretagogin is Expressed by Developing Neocortical GABAergic Neurons in Humans but not Mice and Increases Neurite Arbor Size and Complexity. Cereb Cortex 28:1946-1958 Baud, Maxime O; Kleen, Jonathan K; Mirro, Emily A et al. (2018) Multi-day rhythms modulate seizure risk in epilepsy.

Nat Commun 9:88 Larimer, Phillip; Spatazza, Julien; Stryker, Michael P et al. (2017) Development and long-term integration of MGE-lineage cortical interneurons in the heterochronic environment. J Neurophysiol 118:131-139 Rao, Vikram R; Leonard, Matthew K; Kleen, Jonathan K et al.

(2017) Chronic ambulatory electrocorticography from human speech cortex. Neuroimage 153:273-282 Berer, Kerstin; Gerdes, Lisa Ann; Cekanaviciute, Egle et al. (2017) Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice.

Proc Natl Acad Sci U S A 114:10719-10724 Blanchfield, Lori; Sabatino Jr, Joseph J; Lawrence, Laurel et al. (2017) NFM Cross-Reactivity to MOG Does Not Expand a Critical Threshold Level of High-Affinity T Cells Necessary for Onset of Demyelinating Disease. J Immunol 199:2680-2691 Sabatino Jr, Joseph J; Mehta, Neil J; Kakar, Sanjay et al.

(2017) Acute liver injury in a Glatopa-treated patient with MS. Neurol Neuroimmunol Neuroinflamm 4:e368 Showing the most recent 10 out of 27 publications Be the first to comment on Scott Josephson's grant