NIOSH Exploratory/Developmental Grant Program (R21)

NIOSH Exploratory/Developmental Grant Program (R21) is sponsored by Centers for Disease Control and Prevention (CDC). Supports innovative research projects aimed at understanding and preventing occupational diseases and injuries, including the development of new tools or technologies for occupational safety and health.

Expired PAR-09-139: NIOSH Exploratory and/or Developmental Grant Program (R21) This notice has expired. Check the NIH Guide for active opportunities and notices. Part I Overview Information Department of Health and Human Services Participating Organizations Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health (CDC/NIOSH), ( http://www.

cdc. gov/niosh/oep ) Components of Participating Organizations National Institute for Occupational Safety and Health (NIOSH), ( http://www. cdc.

gov/niosh/oep) Title: NIOSH Exploratory and/or Developmental Grant Program (R21) The policies, guidelines, terms, and conditions of the HHS Centers for Disease Control and Prevention (CDC) stated in this announcement might differ from those used by the HHS National Institutes of Health (NIH).

If written guidance for completing this application is not available on the CDC website, then CDC will direct applicants elsewhere for that information. program is described in the Catalog of Federal Domestic Assistance at http://www. cfda.

gov/ and is not subject to the intergovernmental review requirements of Executive Order 12372 or Health Systems Agency Review.

Awards are made under the authorization of the Occupational Safety and Health Act of 1970, Section 20(a) and 21(a) (29 USC 669(a) and 29 USC 670); Federal Mine Safety and Health Act, Section 501(a), 30 USC 951(a); Section 301 of the Public Health Service Act as amended (42 USC 241) and under Federal Regulations 42 CFR Part 52 and 45 CFR Parts 74 and 92.

All awards are subject to the terms and conditions, cost principles, and other considerations described in the HHS Grants Policy Statement. Type This Funding Opportunity Announcement (FOA) is a reissue of PAR-06-552 . Update: The following update relating to this announcement has been issued: July 27, 2012 - This PAR has been reissued as PAR-12-252.

October 12, 2011 - See Notice NOT-OH-11-004. The purpose of this Notice is to correct language in the Appendix Materials. August 16, 2010 - IMPORTANT NOTE!

NIH has eliminated the error correction window for due dates of January 25, 2011 and beyond. As of January 25, all corrections must be complete by the due date for an application to be considered on-time. See NOT-OD-10-123 .

September 8, 2010 - Fewer resubmissions will be allowed in the near future. See details at http://grants. nih.

gov/grants/guide/notice-files/NOT-OH-10-008. html This FOA has been updated to reflect the new requirements from NIH’s Enhancing Peer Review Initiative. The new requirements are effective for submissions intended for due dates January 25, 2010 and beyond.

If submitting an application intended for a due date of January 25, 2010 and beyond, follow the guidance below and be sure to use the Adobe-Forms-B version of the application forms and instructions. If applying for a due date before January 25, 2010, follow the guidance in the archived version of this FOA and be sure to use the Adobe-Forms-A version of the application forms and instructions.

NOTICE: Applications submitted in response to this Funding Opportunity Announcement (FOA) for Federal assistance must be submitted electronically through Grants. gov (http://grants. gov/) using the SF424 Research and Related (R&R) forms and the SF424 (R&R) Application Guide.

This FOA must be read in conjunction with the application guidelines included with this announcement in (hereafter called Grants. gov/Apply). A registration process is necessary before submission and applicants are highly encouraged to start the process at least four (4) weeks prior to the grant submission date.

See Section IV . Program Announcement (PA) For Assistance downloading this or any Grants. gov application package, please contact Grants.

gov Customer Support at http://grants. gov/CustomerSupport Catalog of Federal Domestic Assistance Number(s) Release/Posted Date: April 1, 2009 Opening Date: May 5, 2009 (Earliest date an application may be submitted Letters of Intent Receipt Date(s): Not Required. NOTE: On-time submission requires that applications be successfully submitted to Grants.

gov no later than 5:00 p. m. local time (of the applicant institution/organization).

Application Due Date(s): Standard dates apply, please see http://grants1. nih. gov/grants/funding/submissionschedule.

htm Peer Review Date(s): Standard dates apply, please see http://grants1. nih. gov/grants/funding/submissionschedule.

htm#reviewand Council Review Date(s): Standard dates apply, please see http://grants1. nih. gov/grants/funding/submissionschedule.

htm#reviewand Earliest Anticipated Start Date(s): Standard dates apply, please see http://grants1. nih. gov/grants/funding/submissionschedule.

htm#reviewand Additional Information To Be Available Date ( URL Activation Date): Not Expiration Date: September 8, 2012 Additional Overview Content National Institute for Occupational Safety and Health (NIOSH) within the Centers for Disease Control and Prevention (CDC) invites grant applications for research related to occupational safety and health.

purpose of this grants program is to develop an understanding of the risks and conditions that are associated with occupational diseases and injuries, to explore methods for reducing risks and for preventing or minimizing exposure to hazardous conditions in the workplace, and to translate significant scientific findings into prevention practices and products that will effectively reduce work-related illnesses and injuries.

Mechanism of Support. This FOA will use the NIH Exploratory/Developmental (R21) grant mechanism and runs in parallel with NIOSH’s R01 and R03 mechanisms which have identical scientific Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed activities will vary from application to application, it is anticipated that the size and duration of each award will also vary.

The total amount awarded and the number of awards will depend upon the number of applications, quality, duration, and costs of the applications received. Budget and Project Period. The total project period for an applica t ion submitted in response to this funding opportunity may not exceed two years.

Direct costs are limited to $275,000 over an R21 two-year period, with no more than $200,000 in direct costs allowed in any single year. The R21 is not renewable. Research Strategy Length: The R21 Research Strategy section may not exceed 6 pages, including tables, graphs, figures, diagrams, and charts.

See http://enhancing-peer-review. nih. gov/page_limits.

html . Institutions/Organizations. Institutions/organizations listed in Section III are eligible to apply.

Eligible Project Directors/Principal Investigators (PDs/PIs). Include Individuals with the skills, knowledge, and resources necessary to carry out the proposed research are invited to work with their institution/organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIOSH Number of PDs/PIs.

More than one PD/PI (i.e., multiple PDs/PIs), may be designated on the application. Number of Applications. Applicants may submit more than one application, provided that each application is scientifically distinct.

Applicants may submit a resubmission application, but such application must include an Introduction addressing the previous peer review critique (Summary Renewals. Exploratory/developmental grant support is for new projects only; competing renewal (formerly competing continuation ) applications will not be accepted. Materials.

See SectionIV1 for application materials. general information on SF424 (R&R) Application and Electronic Submission, SF424 (R&R) Application and Electronic Submission Information: (see http://grants. nih.

gov/grants/funding/424/index. htm ) General information on Electronic Submission of Grant applications: http://era. nih.

gov/ElectronicReceipt/ Hearing Impaired : Telecommunications for the hearing impaired are available at: TTY 770-488-2783. Part I Overview Information Part II Full Text of Announcement Section I. Funding Opportunity Description Section II.

Award Information 1. Mechanism(s) of Support Section III. Eligibility Information 2.

Cost Sharing or Matching 3. Other-Special Eligibility Criteria Section IV. Application and Submission Information 1.

Request Application Information 2. Content and Form of Application Submission 3. Submission Dates and Times A.

Submission, Review, and B. Submitting an Application Electronically to the NIH C. Application Processing 4.

Intergovernmental Review 6. Other Submission Requirements and Section V. Application Review 2.

Review and Selection Process A. Additional Review Criteria B. Additional Review Considerations C.

Resource Sharing Plan(s) 3. Anticipated Announcement and Award Dates Section VI. Award Administration Information 2.

Administrative and National Policy Requirements Section VII. Agency Contact(s) 1. Scientific/Research Contact(s) 2.

Peer Review Contact(s) 3. Financial/Grants Management Contact(s ) Section VIII. Other Information Required Federal Part II - Full Text of Announcement Section I.

Funding Opportunity Description day, approximately 200 million U.S. workers go to work with the expectation that they will return home healthy and safe. However, the workplace environment has a significant impact on a worker’s physical and psychological health. Depending on the job, a worker may be at risk for many different kinds of injuries and illnesses.

Recent estimates are that 9,000 workers sustain disabling injuries every day, and that 16 workers die each day from an injury suffered on the job while another 137 die from diseases they suffer as the result of their current or former occupations. Such statistics translate into tremendous economic costs and societal burdens.

In addition to the personal and social consequences, work-related injuries and illnesses result in a significant economic burden to employers. The Liberty Mutual 2005 Workplace Safety Index estimates that employers spent $50. 8 billion in 2003 on wage payments and medical care for workers hurt on the job.

All of these figures may be significantly underestimated given that many illnesses and diseases such as cancer, diabetes, heart disease, and asthma are only now becoming recognized as being associated with occupational exposures that The evolution and vitality of the biomedical sciences require a constant infusion of new ideas, techniques, and points of view.

These may differ substantially from current thinking or practice and may not yet be supported by substantial preliminary data. By using the R21 mechanism, the NIOSH seeks to foster the introduction of novel scientific ideas, model systems, tools, agents, targets, and technologies that have the potential to substantially advance biomedical research.

The R21 mechanism is intended to encourage new exploratory and developmental research projects. For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance health-related research. Another example could include the unique and innovative use of an existing methodology to explore a new scientific area.

These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. Applications for R21 awards should describe projects distinct from those supported through the traditional R01 mechanism.

For example, long-term projects, or projects designed to increase knowledge in a well-established area, will not be considered for R21 awards. Applications submitted under this mechanism should be exploratory and novel. These studies should break new ground or extend previous discoveries toward new directions or applications.

Projects of limited cost or scope that use widely accepted approaches and methods within well established fields are better suited for the R03 small grant mechanism. Information on the R03 program can be found at http://grants. nih.

gov/grants/guide/pa-files/PAR-09-138. html . In 1996, NIOSH and its partners in the public and private sectors developed the NORA to provide a framework to guide occupational safety and health research into the next decade.

Approximately 500 organizations and individuals outside NIOSH provided input into the development of NORA. The agenda identifies 21 research priorities and reflects an attempt to consider both current and emerging needs. The priority areas were not ranked; each is considered to be of equal importance.

Potential applicants may obtain a copy of the "National Occupational Research Agenda" (HHS, CDC, NIOSH Publication No.96-115) from the National Institute for Occupational Safety and Health, telephone (800) 356-4674 or on the internet at http://www. cdc.

gov/niosh/nora/ (click on About NORA and first agenda ) Objectives of research supported by NIOSH include, but are not limited to: (1) identify and investigate the relationships between hazardous working conditions and associated occupational diseases and injuries; (2) develop more sensitive means of evaluating hazards at work sites, as well as methods for measuring early markers of adverse health effects and injuries; (3) develop new protective equipment, engineering control technology, and work practices to reduce the risks of occupational hazards; (4) evaluate the technical feasibility or application of a new or improved occupational safety and health procedure, method, technique, or system.

The goal of the NIOSH research program is to support research that is relevant, of high quality, and demonstrates impact in reducing occupational disease and injury. Emphasis is placed on research projects that address needs in NORA. In 2006, NIOSH is extending NORA for another ten years with a shift in organization of the research portfolio to reflect the industries in which workers are employed.

In that context, NIOSH created a Program Portfolio to broadly guide activities by categorizing programs into eight (8) NORA Sector Programs that represent groups of industrial sectors, and twenty-four (24) cross-sector programs organized around adverse health outcomes, statutory programs and global efforts. http://www. cdc.

gov/niosh/programs/ The NIOSH Program Portfolio is outlined Agriculture, Forestry & Fishing Healthcare & Social Assistance Mining (including Oil and Gas Extraction) Public and Private Services Transportation, Warehousing & Utilities NIOSH Cross-Sector Programs Authoritative Recommendations Development Cancer, Reproductive, Cardiovascular, Neurological & Renal Communications & Information Dissemination Emergency Preparedness/Response Health Hazard Evaluation (HHE) Immune/Dermal/Infectious Diseases Musculoskeletal Disorders Occupational Health Disparities Personal Protective Technology Prevention through Design Radiation Dose Reconstruction Small Business Assistance and Outreach Work Organization & Stress-Related Disorders Applicants should provide a statement about which industry sector, cross-sector, and emphasis area (if applicable) are being addressed and a rationale for how the proposal will contribute to the specified priority area (this information should be placed in the "Background and Significance" section of the "Research Plan" of the application).

In addition to NORA, NIOSH has initiated a Research to Practice (r2P) initiative to reduce or eliminate occupational disease and injury by increasing the use and translation of effective NIOSH-funded research findings in the workplace and through stakeholder involvement in the research process. Therefore, applications should include an explanation of how their proposed research will contribute to this initiative.

Information is available at: http://www. cdc. gov/niosh/r2p/ .

SectionVIII , for policies related to Section II. Award Information This FOA will use the NIH Exploratory/Developmental Research Grant (R21) award mechanism. The Project Director/Principal Investigator (PD/PI) will be solely responsible for planning, directing, and executing the proposed This FOA uses Just-in-Time information concepts (see SF424 (R&R) Application and Electronic Submission Information ).

All applicants must complete and submit budget requests using the Research & Related Budget (detailed budget format) component. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary.

Although the financial plans of the National Institute for Occupational Safety and Health provide support for this program, awards pursuant to this funding opportunity are contingent upon the availability of funds and the submission of a sufficient number of meritorious The total project period for an application submitted in response to this funding opportunity may not exceed 2 years.

Although the size of award may vary with the scope of research proposed, it is expected that applications will stay within the budgetary guidelines for an exploratory/developmental project; direct costs are limited to $275,000 over an R21 two-year period, with no more than $200,000 in direct costs allowed in any single year..

NIOSH grants policies as described in the HHS Grants Policy Statement will apply to the applications submitted and awards made in response to this F&A costs requested by consortium participants are not included in the direct cost limitation. See http://grants. nih.

gov/grants/guide/notice-files/NOT-OD-05-004. html , Section III. Eligibility Information 1.

A.

Eligible Institutions The following organizations/institutions are eligible to apply: Institutions of Higher Education Private Institutions of Higher Hispanic-serving Institutions Historically Black Colleges and Tribally Controlled Colleges and and Native Hawaiian Serving Institutions Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education) Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education) For-Profit Organizations (Other Indian/Native American Tribal Governments (Federally Recognized) Indian/Native American Tribally City or Township Governments Special District Governments Independent School Districts Public Housing Authorities/Indian Indian/Native American Tribal Governments (Other than Federally Recognized) Eligible Agencies of the Federal Faith-based or Community -based Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible.

1. B. Eligible Individuals Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the PD/PI is invited to work with his/her organization to develop an application for support.

Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply More than one PD/PI (i.e., multiple PDs/PIs), may be designated on the application for projects that require a team science approach and therefore clearly do not fit the single-PD/PI model.

Additional information on the implementation plans and policies and procedures to formally allow more than one PD/PI on individual research projects is available at http://grants. nih. gov/grants/multi_pi .

All PDs/PIs must be registered in the NIH electronic Research Administration (eRA) Commons prior to the submission of the application (see http://era. nih. gov/ElectronicReceipt/preparing.

htm for instructions). The decision of whether to apply for a grant with a single PD/PI or multiple PDs/PIs grant is the responsibility of the investigators and applicant organizations and should be determined by the scientific goals of the project. Applications for grants with multiple PDs/PIs will require additional information, as outlined in the instructions below.

The NIOSH review criteria for approach, investigators, and environment have been modified to accommodate applications involving either a single PD/PI or multiple PDs/PIs.

When considering the multiple PD/PI option, please be aware that the structure and governance of the PD/PI leadership team as well as the knowledge, skills and experience of the individual PDs/PIs will be factored into the assessment of the overall scientific merit of the application. Multiple PDs/PIs on a project share the authority and responsibility for leading and directing the project, intellectually and logistically.

Each PD/PI is responsible and accountable to the grantee organization, or, as appropriate, to a collaborating organization, for the proper conduct of the project or program, including the submission of required reports. For further information on multiple PDs/PIs, please see http://grants. nih.

gov/grants/multi_pi . 2. Cost Sharing or Matching This program does not require cost sharing as defined in the current HHS Grants Policy Statement .

3. Other-Special Eligibility Criteria Applications. Applicants may submit more than one application, provided each application is scientifically distinct.

Resubmissions. Applicants may submit one resubmission, but such application must include an Introduction addressing issues raised in the previous critique (Summary Statement). See NOT-OD-03-041 , Renewals.

Exploratory/developmental grant support is for new projects only; competing renewal (formerly competing continuation ) applications will not be accepted. Section IV. Application and Submission Information To download a SF424 (R&R) Application Package and SF424 (R&R) Application Guide for completing the SF424 (R&R) forms for this FOA, use the Apply for Grant Electronically button in this FOA or link to http://www.

grants. gov/Apply/ and follow the directions provided on that Web site. registrations with Grants.

gov and eRA Commons must be completed on or before the due date in order to successfully submit an application . Several of the steps of the registration process could take four weeks or more. Therefore, applicants should immediately check with their business official to determine whether their organization/institution is already registered with both Grants.

gov and the Commons . All registrations must be complete by the submission deadline for the application to be considered on-time (see 3. C.

1 for more information about on-time submission). A one-time registration is required for institutions/organizations at both: Grants. gov (http://www.

grants. gov/applicants/get_registered. jsp) and eRA Commons (http://grants.

nih. gov/grants/ElectronicReceipt/preparing. htm) PDs/PIs should work with their institutions/organizations to make sure they are registered in the NIH eRA Commons.

Several additional separate actions are required before an applicant can submit an electronic application, as follows: 1) Organizational/Institutional Registration in http://www. grants. gov/applicants/get_registered.

jsp . Your organization will need to obtain a DUNS number ( http://fedgov. dnb.

com/webform ) and register with the Central Contractor Registration (CCR) as part of the Grants. gov registration process. If your organization does not have a Taxpayer Identification Number (TIN) or Employer Identification Number (EIN), allow for extra time.

A valid TIN or EIN is necessary for CCR registration. The CCR also validates the EIN against Internal Revenue Service records, a step that will take an additional one to two business days Direct questions regarding Grants. gov registration to: Business Hours: M-F 7:00 a.

m. - 9:00 p. m.

Eastern Time 2) Organizational/Institutional Registration in the eRA Commons Prepare to Apply https://commons. era. nih.

gov/commons/registration/registrationInstructions. jsp To find out if an organization is already Commons-registered, see Organizations Registered in eRA Commons. Direct questions regarding the Commons registration to: Phone: 301-402-7469 or 866-504-9552 (Toll Free) Business hours M-F 7:00 a.

m. 8:00 p. m.

Eastern Time 3) Project Director/Principal Investigator (PD/PI) Registration in the NIH eRA Commons: Refer to the NIH eRA Commons System (COM) The individual designated as the PD/PI on the application must also be registered in the NIH eRA Commons. It is not necessary for PDs/PIs to register with Grants. gov. The PD/PI must hold a PD/PI account in the Commons and must be affiliated with the applicant organization.

This account cannot have any other role attached to it other than the PD/PI. This registration/affiliation must be done by the Authorized Organization Representative/Signing Official (AOR/SO) or their designee who is already registered in the Commons. Both the PD/PI and AOR/ SO need separate accounts in the NIH eRA Commons since both are authorized to view the application image.

process is not sequential. Applicants should begin the registration processes for both Grants. gov and eRA Commons as soon as their organization has obtained a DUNS number.

Only one DUNS number is required and the same DUNS number must be referenced when completing Grants. gov registration, eRA Commons registration and the SF424 (R&R) forms. 1.

Request Application Information Applicants must download the SF424 (R&R) application forms and SF 424 (R&R) Application Guide for this FOA through grants. gov/Apply . Note: Only the forms package directly attached to a specific FOA can be used.

You will not be able to use any other SF424 (R&R) forms (e.g., sample forms, forms from another FOA), although some of the "Attachment" files may be useable for more than one FOA. For further assistance, contact GrantsInfo: Email: Grants. gov/Apply ..

Telecommunications for the hearing impaired: TTY 770-488-2783. 2. Content and Form of Application Submission Prepare all applications using the SF424 (R&R) application forms and in accordance with the SF424 (R&R) Application Guide ( http://grants.

nih. gov/grants/funding/424/index. htm ).

. The SF424 (R&R) Application Guide is critical to submitting a complete and accurate application to NIOSH. There are fields within the SF424 (R&R) application components that, although not marked as mandatory, are required by NIOSH (e.g., the Credential log-in field of the Research & Related Senior/Key Person Profile component must contain the PD/PI’s assigned eRA Commons User ID).

Agency-specific instructions for such fields are clearly identified in the Application Guide. For additional information, see Frequently Asked Questions Application Guide, Electronic Submission of Grant The SF424 (R&R) application is comprised of data arranged in separate components. Some components are required, others are optional.

The forms package associated with this FOA in Grants. gov/Apply will include all applicable components, required and optional.

A completed application in response to this FOA will include the following components: SF424 (R&R) (Cover component) Research & Related Project/Performance Site Locations Research & Related Other Project Information Research & Related Senior/Key Person PHS398 Cover Page Supplement Note: While both budget components are included in the SF424 (R&R) forms package, the NIOSH R21 uses ONLY the PHS398 Research & Related Research & Related Subaward Budget Attachment(s) Form Applications with Multiple When multiple PDs/PIs are proposed, NIOSH requires one PD/PI to be designated as the "Contact PI, who will be responsible for all communication between the PDs/PIs and the NIH, for assembling the application materials outlined below, and for coordinating progress reports for the project.

The contact PD/PI must meet all eligibility requirements for PD/PI status in the same way as other PDs/PIs, but has no other special roles or responsibilities within the project team beyond those Information for the Contact PD/PI should be entered on the SF424 (R&R) Cover component. All other PDs/PIs should be listed in the Research & Related Senior/Key Person component and assigned the project role of PD/PI.

Please remember that all PDs/PIs must be registered in the eRA Commons prior to application submission . The Commons ID of each PD/PI must be included in the Credential field of the Research & Related Senior/Key Person component.

Failure to include this data field will cause the application Multiple PD/PI Leadership Plan: For applications designating multiple PDs/PIs, a new section of the research plan, entitled Multiple PD/PI Leadership Plan must be included. A rationale for choosing a multiple PD/PI approach should be described.

The governance and organizational structure of the leadership team and the research project should be described, and should include communication plans, process for making decisions on scientific direction, and procedures for resolving conflicts. The roles and administrative, technical, and scientific responsibilities for the project or program should be delineated for the PDs/PIs and other collaborators.

If budget allocation is planned, the distribution of resources to specific components of the project or the individual PDs/PIs should be delineated in the Leadership Plan.

In the event of an award, the requested allocations may be reflected in a footnote on the Applications Involving a Single When all PDs/PIs are within a single institution, follow the instructions contained in the SF424 (R&R) Applications Involving Multiple When multiple institutions are involved, one institution must be designated as the prime institution and funding for the other institution(s) must be requested via a subcontract to be administered by the prime institution.

When submitting a detailed budget, the prime institution should submit its budget using the Research & Related Budget component. All other institutions should have their individual budgets attached separately to the Research & Related Subaward Budget Attachment(s) Form. See Section 4.

8 of the SF424 (R&R) Application Guide for further instruction regarding the use of the subaward budget form. When submitting a modular budget, the prime institution completes the PHS398 Modular Budget component only. Information concerning the consortium/subcontract budget is provided in the budget justification.

Separate budgets for each consortium/subcontract grantee are not required when using the Modular budget format. See Section 5. 4 of the Application Guide for further instruction regarding the use of the PHS398 Modular Budget component.

3. Submission Dates and Times Review, and Anticipated Start Dates Opening Date: May 5, 2009 (Earliest date an application may be submitted to Letter of Intent Receipt Date(s): Not Application Due Date(s): Standard dates apply, please see http://grants1. nih.

gov/grants/funding/submissionschedule. htm http://grants1. nih.

gov/grants/funding/submissionschedule. htm Council Review Date(s): Standard dates apply, please see http://grants1. nih.

gov/grants/funding/submissionschedule. htm Earliest Anticipated Start Date(s): Standard dates apply, please see http://grants1. nih.

gov/grants/funding/submissionschedule. htm A letter of intent is not required for the funding opportunity. 3.

B. Submitting an Application Electronically to the NIH Applications submitted to NIOSH are processed through NIH. To submit an application in response to this FOA, applicants should access this FOA via http://www.

grants. gov/Apply/ and follow Steps 1-4. Note: Applications must only be submitted electronically .

PAPER APPLICATIONS WILL NOT BE ACCEPTED. 3. C.

Application Processing Applications may be submitted on or after the opening date and must be successfully received by Grants. gov no later than 5:00 p. m.

local time (of the applicant institution/organization) on the application due date(s). (See SectionIV3A for all dates.) If an application is not submitted by the due date(s) and time, the application may be delayed in the review process or not reviewed.

PAPER APPLICATIONS WILL NOT BE ACCEPTED. All attachments must be provided to NIH in PDF format, filenames must be included with no spaces or special characters, and a . pdf extension must be used.

Applications may be submitted on or after the successfully received by Grants. gov no later than 5:00 p. m.

local time (of the applicant institution/organization) on the application due date(s). (See Section IV. 3.

A. for all dates.) If an application is not submitted by the due date(s) and time, the application may be delayed in the review process or not reviewed.

All applications must meet the following criteria to be considered on-time : registrations must be complete prior to the submission deadline application must receive a Grants. gov tracking number and timestamp (or eRA help desk ticket confirming a system issue preventing submission) by 5:00 p. m.

local time on the submission deadline date. system identified errors/warnings must be corrected and the submission process completed within the error correction window. visit http://era.

nih. gov/electronicReceipt/app_help. htm for detailed information on what to do if Grants.

gov or eRA system issues threaten your ability to submit on time. Submission to Grants. gov is not the last step applicants must follow their application through to the eRA Commons to check for errors and warnings and view their assembled application!

3. C. 2 Two Day Window to Correct eRA Identified Errors/Warnings IMPORTANT NOTE!

NIH has eliminated the error correction window for due dates of January 25, 2011 and beyond. As of January 25, all corrections must be complete by the due date for an application to be considered on-time. See Once an application package has been successfully submitted through Grants.

gov, NIOSH and the NIH provides applicants a two day error correction window to correct any eRA identified errors or warnings before the assembled application has been created in the eRA Commons. The standard error correction window is two (2) business days, beginning the day after the submission deadline and excluding weekends and standard federal holidays. All errors must be corrected to successfully complete the submission process.

Warnings will not prevent the application from completing the submission process. , Please note that the following application submission must be on-time. AOR/institutions is expected to enforce that application changes made within the error correction window are restricted to those necessary to address system-identified errors/warnings.

NIH may reject any application that includes additional changes. on-time submission (e.g., Grants. gov timestamp and tracking number) and description of all changes made within the window must be documented in the PHS 398 Cover Letter component of the application.

3. C. 3 Viewing an Application in Once any eRA identified erros have been addressed and the assembled application has been created in the eRA Commons, the PD/PI and the Authorized Organization Representative/Signing Official (AOR/SO) have two seekdays (Monday Friday, excluding Federal holidays) to view the assembled application before it automatically moves forward for If everything is acceptable, no further action is necessary.

The application will automatically move forward to the Division of Receipt and Referral in the Center for Scientific Review for processing after two weekdays, excluding Federal holidays. Prior to the submission deadline, the AOR/SO can Reject the assembled application and submit a changed/corrected application within the two-day viewing window.

This option should be used if it is determined that some part of the application was lost or did not transfer correctly during