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NSF EPSCoR Research Infrastructure Improvement Program: EPSCoR Collaborations for Optimizing Research Ecosystems (NSF E-CORE) is a grant from the U.S. National Science Foundation that funds jurisdiction-wide research ecosystem strengthening in EPSCoR-eligible states, territories, and commonwealths including Vermont.
The program supports research institutions and universities in building interconnected networks and sustainable research infrastructure across cores such as research administration, facilities and cyberinfrastructure, STEM education pathways, broadening participation, workforce development, technology transfer, and use-inspired research.
Projects must be designed for sustainability beyond the award period and must build or leverage jurisdiction-wide connections to drive measurable impact. The NSF's EPSCoR program promotes scientific progress nationwide by fostering partnerships among academic institutions, government entities, industry, and nonprofits. Multiple application deadlines are available in 2026, including May 7, May 27, June 17, July 9, and July 16.
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EPSCoR Research Infrastructure Improvement Program: EPSCoR Collaborations for Optimizing Research Ecosystems (E-CORE) | NSF - U.S. National Science Foundation EPSCoR Research Infrastructure Improvement Program: EPSCoR Collaborations for Optimizing Research Ecosystems (E-CORE) NSF's implementation of the revised 2 CFR NSF Financial Assistance awards (grants and cooperative agreements) made on or after October 1, 2024, will be subject to the applicable set of award conditions, dated October 1, 2024, available on the NSF website .
These terms and conditions are consistent with the revised guidance specified in the OMB Guidance for Federal Financial Assistance published in the Federal Register on April 22, 2024.
Important information for proposers All proposals must be submitted in accordance with the requirements specified in this funding opportunity and in the NSF Proposal & Award Policies & Procedures Guide (PAPPG) that is in effect for the relevant due date to which the proposal is being submitted. It is the responsibility of the proposer to ensure that the proposal meets these requirements.
Submitting a proposal prior to a specified deadline does not negate this requirement.
Updates to NSF Research Security Policies On July 10, 2025, NSF issued an Important Notice providing updates to the agency's research security policies, including a research security training requirement, Malign Foreign Talent Recruitment Program annual certification requirement, prohibition on Confucius institutes and an updated FFDR reporting and submission timeline.
Supports the strengthening of jurisdiction-wide research ecosystems by fostering interconnected networks and building research infrastructure to grow research capacity and competitiveness aligned with jurisdictional priorities.
Supports the strengthening of jurisdiction-wide research ecosystems by fostering interconnected networks and building research infrastructure to grow research capacity and competitiveness aligned with jurisdictional priorities. The Established Program to Stimulate Competitive Research (EPSCoR) supports the U.S. National Science Foundation (NSF) mission by promoting nationwide scientific progress.
Through this program, NSF fosters partnerships among academic institutions, government entities, industry, and non-profits. These collaborations aim to drive long-term improvements in research infrastructure, enhance R&D capacity, and boost the research competitiveness of eligible EPSCoR jurisdictions, including states, territories, and commonwealths.
A jurisdiction’s research ecosystem is the interconnected network of organizations, researchers, trainees, community stakeholders, and resources that contribute to the process of research and innovation that advances fundamental knowledge, generates use-inspired products, and ultimately cultivates beneficial impacts for a jurisdiction.
E-CORE supports jurisdictions in building significant and sustainable research capacity and research infrastructure for targeted areas of focus, hereinafter referred to as “cores,” that underlie a jurisdiction's research ecosystem.
Based on the evidence-based and self-identified needs of a jurisdiction, the types of cores supported by E-CORE may include (but are not limited to) development, enhancement, and/or ensuring the sustainability of: research administration; research facilities and infrastructure (including cyberinfrastructure); STEM education (K-12) pathways; higher education pathways; early career investigator pathways; broadening participation; workforce development; national and global partnerships; community engagement and outreach; technology transfer; economic development; and use-inspired research pathways.
E-CORE projects must be designed to support the sustainability of the research infrastructure cores beyond the award period. Projects will also support the development and growth of new jurisdiction-wide connections, and the leveraging of existing jurisdiction-wide connections, to drive substantive and sustainable impacts.
May 7, 2026 - NSF EPSCoR Collaborations for Optimizing Research Ecosystems Research Infrastructure… May 27, 2026 - NSF EPSCoR Collaborations for Optimizing Research Ecosystems Research Infrastructure… June 17, 2026 - NSF EPSCoR Collaborations for Optimizing Research Ecosystems Research… July 9, 2026 - NSF EPSCoR Collaborations for Optimizing Research Ecosystems Research Infrastructure… July 16, 2026 - NSF EPSCoR Collaborations for Optimizing Research Ecosystems Research… April 16, 2026 - NSF EPSCoR Collaborations for Optimizing Research Ecosystems… March 18, 2026 - NSF EPSCoR Collaborations for Optimizing Research Ecosystems… April 14, 2025 - E-CORE Office Hours July 17, 2024 - EPSCoR Live!
April 30, 2024 - EPSCoR Live! Awards made through this program Browse projects funded by this program Map of recent awards made through this program Office of Integrative Activities (OD/OIA)
According to the current listing, eligibility includes: Research institutions, universities, and collaborating institutions in Vermont. Confirm the full requirements in the official notice before applying.
NSF EPSCoR Research Infrastructure Improvement Program: EPSCoR Collaborations for Optimizing Research Ecosystems (NSF E-CORE) is funded by U.S. National Science Foundation (NSF). Verify program details on the funder's official page before applying.
This opportunity targets applicants in Vermont. If your organization operates elsewhere, check the official notice for location requirements.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
On October 28, 2026, NSF sent its revised Guidance on Financial Assistance to OMB after 3,277 public responses. The revision drops four provisions borrowed from OMB's unfinished 2 CFR 200 rewrite: no fixed-price awards, no publication costs, termination for convenience, and indirect costs subject to available funds. The final 30-day comment period runs through about November 27. Here is what changed, what didn't, and what research offices should do before the December 11 funding cliff.
Read articleNSF 26-022, the July 8, 2026 Dear Colleague Letter last updated October 27, says NSF will prohibit its funds from supporting research collaborations with entities on U.S. restricted-party lists in FY2027, on the same timeline as the Guidance on Financial Assistance. Authorized organizational representatives and senior/key personnel will certify compliance at proposal submission. Here is what is covered, what is still undefined, and a 60-day plan for research offices and PIs.
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