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The NSF FDT-BioTech program, a joint initiative of the National Science Foundation, National Institutes of Health, and the Food and Drug Administration, supports inherently interdisciplinary research projects that underpin the mathematical and engineering foundations behind the development and use of digital twins and synthetic data in biomedical and healthcare applications.
The program has a particular focus on digital, in silico models used in the evaluation of medical devices. Projects combine AI and machine learning with mathematical sciences and domain knowledge to develop computational models that can simulate biological systems, predict treatment outcomes, and accelerate medical device evaluation.
Each project requires at least two collaborating Senior/Key Personnel with participation from both mathematical sciences and at least one domain knowledge discipline. The program runs annually with a deadline on the first Monday in May.
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Search similar grants →Based on current listing details, eligibility includes: Proposals accepted only from accredited Institutions of Higher Education (IHEs) located in the United States. Each PI or co-PI is limited to one proposal maximum per cycle. Minimum requirement of at least two collaborating Senior/Key Personnel with participation from both mathematical sciences and at least one domain knowledge discipline. Collaborative projects from multiple organizations must not exceed $1,000,000 total budget. Applicants should confirm final requirements in the official notice before submission.
Current published award information indicates Up to $1,000,000 per collaborative project from multiple organizations over up to 3 years. Total program funding approximately $4,000,000 to $5,000,000 annually across 6-10 awards. First cohort awarded over $6 million across seven projects. Always verify allowable costs, matching requirements, and funding caps directly in the sponsor documentation.
The current target date is May 4, 2026. Build your timeline backwards from this date to cover registrations, approvals, attachments, and final submission checks.
Federal grant success rates typically range from 10-30%, varying by agency and program. Build a strong proposal with clear objectives, measurable outcomes, and a well-justified budget to improve your chances.
Requirements vary by sponsor, but typically include a project narrative, budget justification, organizational capability statement, and key personnel CVs. Check the official notice for the complete list of required attachments.
Yes — AI tools like Granted can help research funders, draft proposal sections, and check compliance. However, always review and customize AI-generated content to reflect your organization's unique strengths and the specific requirements of the solicitation.
Review timelines vary by funder. Federal agencies typically take 3-6 months from submission to award notification. Foundation grants may be faster, often 1-3 months. Check the program's timeline in the official solicitation for specific dates.
Many federal programs offer multi-year funding or allow competitive renewals. Check the official solicitation for continuation and renewal policies. Non-competing continuation applications are common for multi-year awards.
EPAs SmartWay Transport Partnership and National Clean Diesel Campaign (NCDC) are announcing the availability of funding assistance to create finance programs, such as low cost leases or revolving loan programs, to achieve significant reductions in diesel emissions throughout the United States. The SmartWay Clean Diesel Finance Program is soliciting proposals for projects that reduce diesel emissions through the creation of national, tribal, regional, state or local finance program(s). Finance programs include, but are not limited to, those that provide the loan recipient a specific financial incentive (i.e., longer terms or lower rates) to purchase or lease eligible retrofitted vehicles or equipment. The proposed finance program should maximize the total project funds available for financing eligible diesel emission reduction solutions and be sustainable to maintain the program. Funding Opportunity Number: EPA-OAR-OTAQ-09-13. Assistance Listing: 66.039. Funding Instrument: CA. Category: ENV. Award Amount: $2M – $12M per award.
The U. S. Environmental Protection Agency Region 2 is soliciting applications for projects that address the 2010 Reduce, Reuse, Recycle, Rebuy (4Rs) in Schools Program goals from applicants carrying out or desiring to carry out projects that serve EPA Region 2: New York, New Jersey, Puerto Rico, and Virgin Islands. Applicantsare required to be members of, or to join, EPAs WasteWise program in order to apply.See subsection E for more information. Funding Opportunity Number: EPA-R2-RPB-01-2010. Assistance Listing: 66.808. Funding Instrument: CA. Category: ENV. Award Amount: $60K total program funding.
The Healthy Communities Grant Program is seeking projects that: Target resources to benefit communities at risk (environmental justice areas of potential concern, places with high risk from toxic air pollution, urban areas) and sensitive populations (e.g. children, elderly, others at increased risk). Assess, understand, and reduce environmental and human health risks. Increase collaboration through community-based projects. Build institutional and community capacity to understand and solve environment and human health problems. Achieve measurable environmental and human health benefits. Proposed projects must: (1) Be located in and/or directly benefit one or more of the three Target Investment Areas which include: Environmental Justice Areas of Potential Concern, Sensitive Populations, and/or Urban Areas in one or more of the EPA Region I States of Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, and/or Vermont; and (2) Identify how the proposed project will achieve measurable environmental and/or public health results in one or more of the five Target Program Areas which include Asthma, Capacity Building on Environmental and Public Health Issues, Healthy Indoor/Outdoor Environments, Healthy Schools, Urban Natural Resources. Funding Opportunity Number: EPA-R1-HC-2010. Assistance Listing: 66.110. Funding Instrument: CA. Category: ENV. Award Amount: $5K – $35K per award.