Opioid and Overdose Crisis Grants

Opioid and Overdose Crisis Grants is sponsored by Foundation for Opioid Response Efforts (FORE). Grants supporting organizations across the U. S.

working to save lives, strengthen communities, and respond to the opioid and overdose crisis.

You are using an outdated browser. Please upgrade your browser to improve your experience. We fund projects from nonprofit organizations, universities, and government agencies focused on health care professional education, payer & provider strategies, policy initiatives, and public awareness.

Now more than ever, it is critical for us to think creatively, test new approaches, remove silos, and enhance and expand activities proven to prevent and reduce opioid use disorder.

We are committed to fostering new ideas and approaches and scaling those activities that are already showing evidence-based results across the continuum of prevention, treatment, and recovery in four key areas: Professional education, payer & provider strategies, policy initiatives, and public awareness.

Generally, FORE will consider grant requests for specific projects from U.S.-based public charities that are tax-exempt under section 501(c)(3) of the Internal Revenue Code, as well as from nonprofit, tax-exempt universities. The Foundation will also consider grant requests from state, local, and Native American tribal government units or agencies for specific charitable projects .

FORE will not provide grants to Section 509(a)(3) supporting organizations, congregational religious organizations, or private individuals. General purpose grants and payments to individual government employees or officials are not permitted. The Foundation will not consider grant requests for fundraising events, non-profit and school sponsored athletic-related events, political advocacy and related activities, and endowment funds.

How we develop and administer grant programs: The Foundation will not review unsolicited proposals. Each of our grant programs is developed by FORE program staff, in consultation with leading experts in the field of interest.

In most cases, FORE will issue a Request for Proposal (RFP) which defines the specific focus area we wish to address, as well as activities we will support, the eligibility criteria for the grant program, and the timelines for responding. In general , the first step in the RFP application process is to submit a Letter of Intent (LOI) or short Concept Note.

FORE will evaluate all LOIs and/or Concept Notes for responsiveness and alignment to the RFP and seek independent expert review as needed. Program staff will notify selected organizations if there is an interest in seeing a Full Proposal that may be peer-reviewed by a panel of external, independent practitioners and experts. This review process may include feedback to selected applicants on draft proposals and recommended revisions.

All LOIs and Full Proposals must be submitted through the Foundation’s online grants management system . You can view Frequently Asked Questions here . Proposal applications must include organizational information, project leadership, and budget.

FORE provides up to 10% indirect on direct costs.

All proposals will be reviewed for compliance items, including: FORE eligibility guidelines Fully completed proposal application Detailed, line-item proposed project budget and justification narrative Charitable purpose of the proposal Proof of status as a nonprofit, tax-exempt organization Organization’s audited financial statements and budget for current year Funding recommendations for selected, high-quality proposals will be prepared by FORE program staff and presented to the FORE Board of Directors for final approval.

All approved proposals will then be the subject of a grant award agreement between the Foundation and the grantee organization which will specify the grant period, payment schedule, specific deliverable requirements, and reporting timeline.

Past Requests for Proposals Community-Driven Responses to Opioid Use Disorder and Overdose Mortality 2025 Grants supporting community-based organizations’ capacity to address opioid use disorder and overdose mortality through work such as organizational strengthening, program development, and community partnerships.

Funding is for specific activities or projects designed to strengthen an organization’s operations, leadership, technology, programmatic, and administrative capacity.

View recording of Informational Webinar from June 5, 2025 Opioid Crisis Innovation Challenge 2024 Grants support for innovative projects which can explore and/or evaluate new “outside-the-box” ideas, bring together approaches from several diverse fields, and engage multi-disciplinary, cross-sector teams to solve some of the crisis’ most intractable problems.

This opportunity will focus on projects with innovative solutions in the following areas: – Innovative Payment Models – Supporting the Transition from Treatment to Recovery View recording of Informational Webinar from June 27, 2024 Community-Driven Responses to Opioid Use Disorder and Overdose Mortality Grants supporting community-based organizations’ capacity to address opioid use disorder and overdose mortality through work such as organizational strengthening, skills development, and community partnerships.

Funding is for specific activities or projects designed to strengthen an organization’s operations, leadership, technology, programmatic, and administrative capacity to achieve sustainable opioid use disorder mitigation initiatives. Note: This is a one-stage application process. No LOI or Concept Note is required.

View recording of Informational Webinar from September 9, 2022. Engaging and Empowering Vulnerable Families and Communities to Prevent Opioid Use Disorder and Overdose Grants support for projects which can develop, adapt, explore, and/or evaluate promising evidence-based models of family- and community-based prevention for opioid use disorder and overdose, particularly for children and families at highest risk.

This opportunity will focus on projects in the following areas: – Mitigating the Impact of ACEs on Families – Models for Racial and Cultural Minorities to Address Inequities – Addressing Pain, Emotional Distress, and Trauma View recording of Informational Webinar from August 11, 2021 Opioid Crisis Innovation Challenge 2021 Grants support for innovative projects which can explore and/or evaluate new “outside-the-box” ideas, bring together approaches from several diverse fields, and engage multi-disciplinary, cross-sector teams to solve some of the crisis’ most intractable problems.

This opportunity will focus on projects with innovative solutions in the following areas: – Professional Education and Training – Timely and Actionable Data – Supporting the Transition from Treatment to Recovery View recording of Informational Webinar from June 9, 2021 Strengthening Access to Care for Opioid Use Disorder Patients During the COVID-19 National Public Health Emergency: Recovery Support Services Rapid response grant support for projects that aim to strengthen access to evidence-based OUD recovery services during the COVID-19 national emergency.

Targets projects which can provide recovery support services in the context of social distancing and infection control, including promotion of remote, digital, and virtual forms of recovery support to reach vulnerable populations.

Improving Access to Opioid Use Disorder Treatment and Recovery Services for Underserved Populations and Communities Grants program focused on removing barriers and improving access to and quality of MOUD for underserved populations.

Interested projects include those that aim to improve and reform the continuum of care, provide wraparound social services, and address other areas that are necessary to facilitate access to high-quality, patient-centered treatment and improve outcomes.