Oral Microbiome and Polymicrobial Diseases Program

Oral Microbiome and Polymicrobial Diseases Program is sponsored by National Institute of Dental and Craniofacial Research (NIDCR). Supports research on the role of bacteria, fungi, and viruses in oral health and disease, focusing on microbial interactions and resistance mechanisms.

Oral Microbiome and Polymicrobial Diseases Program | NIDCR Oral Microbiome & Polymicrobial Diseases Program The Oral Microbiome and Polymicrobial Disease Program supports basic and translational research on the role of bacteria, fungi and viruses in health and disease in the oral cavity.

Topics include examining the role of the oral microbiome in health and disease; microbial virulence and pathogenesis, including oral opportunistic pathogens; and prevention, diagnosis and treatment of microbial infections. NIDCR encourages research on understanding the complexities of the oral microbiome and the importance in oral and overall health.

Relevant research topics include, but are not limited to: Understanding how biofilm and microbial ecology principles drive the formation, structure, homeostasis, modulation, and eradication of the oral microbiome Oral cavity changes that drive the emergence of pathogenic states and the return to health Mechanisms affecting genetic heterogeneity and antibiotic resistance Stress responses and microbial interactions—from between similar organisms to interkingdom interactions—that modify organism virulence Host factors and underlying immune, molecular, and cellular mechanisms for the elimination of microbial pathogens or maintenance of a healthy oral microbiome Early detection and novel strategies for treatment and prevention of oral disease including periodontitis, caries, candidiasis, HIV, and other viral infections Genomic, proteomic, transcriptomic, and metabolomic studies for understanding of structure, function, and system dynamics Previously Funded Grants (NIH RePORTER) Oral Microbiome & Polymicrobial Diseases Program