PA21259, SBIR, Phase I, Aptamer-upconverting nanocrystal conjugate lateral flow assay for immediate Ebola virus detection

PA21259, SBIR, Phase I, Aptamer-upconverting nanocrystal conjugate lateral flow assay for immediate Ebola virus detection is sponsored by National Center for Zoonotic, Vector-Borne, and Enteric Diseases at CDC. SBIR Phase I project developing an aptamer-upconverting nanocrystal conjugate lateral flow assay for immediate Ebola virus detection.

Recent Grants Related to Ebola Virus Disease – Resources | Paper Digest Hit enter to search or ESC to close Recent Grants Related to Ebola Virus Disease October 29, 2020 August 15, 2026 To help academic community quickly catch up on the most recent research grants awarded by US government, Paper Digest Team extracted all grants related to Ebola Virus Disease on our radar (including old grants related to this topic).

These results are sorted by relevance & date and will be updated on a weekly basis.

New York City, New York, 10017 TABLE 1: Recent Grants Related to Ebola Virus Disease Emerging and Re-Emerging Pathogens Research Training Program in DRC (EREP-RTP-DRC) JEAN-JACQUES TAMFUM MUYEMBE-TAMFUM Training in Clinical and Epidemiological Research for Liberia (TRACER) UNIVERSITY OF CALIFORNIA, SAN FRANCISCO Long-term ocular sequelae and biological determinants of post-acute Ebola virus disease NORTHERN CALIFORNIA INSTITUTE/RES/EDU Armed nanobodies as anti-infectives and anti-tumor agents BOSTON CHILDREN’S HOSPITAL Determinants of viral assembly and infectivity within the Ebola virus VP24 protein SCRIPPS RESEARCH INSTITUTE, THE SCRIPPS RESEARCH INSTITUTE, THE Center for Viral Systems Biology (CViSB) SCRIPPS RESEARCH INSTITUTE, THE Regulation of Filovirus mRNA translation Virion, nucleocapsid, and inclusion body structures of Lloviu and Ebola viruses Optimizing Ridaifen-B analogs as potential therapeutics for Ebola viruses Identifying placental tissue tropism and cellular mechanisms of Ebola Virus transmission from mother to fetus in pregnancy Identifying placental tissue tropism and cellular mechanisms of Ebola Virus transmission from mother to fetus in pregnancy Functional significance and mechanisms of Ebola Virus VP24-host protein interactions Research Project 1: Role of Epigenetic and Transcriptional Mechanisms in the Pathogenesis of Ebola Virus Disease Research Project 2: Role of Posttranscriptional Regulatory Networks in the Pathogenesis of Ebola Virus Disease Molecular Mechanisms of the Dysregulated Immune Response to Ebola Virus Research Project 3: Role of Posttranslational Protein Modifications in the Pathogenesis of Ebola Virus Disease Tolerance and resistance responses of African bats to viral antigens: Immunological tradeoffs in zoonotic reservoir hosts.

Identifying placental tissue tropism and cellular mechanisms of Ebola Virus transmission from mother to fetus in pregnancy Determining Tropism and Mechanisms of Ebola Virus Entry in Placental Tissues MPOPHC: Integrating human risk perception and social processes into policy responses in an epidemiological model SUZANNE LENHART ; BRIAN BECKAGE ; CHARLES SIMS ; KATHERINE LACASSE ; UNIVERSITY OF VERMONT & STATE AGRICULTURAL COLLEGE DANIEL DESIRE TSHALA-KATUMBAY OREGON HEALTH & SCIENCE UNIVERSITY Identifying placental tissue tropism and cellular mechanisms of Ebola Virus transmission from mother to fetus in pregnancy Defining the effect of Plasmodium infection on Ebola virus vaccine efficacy Evaluating the impact of malaria on immunogenicity of the Ebola virus vaccine Optimizing Ridaifen-B analogs as potential therapeutics for Ebola viruses Defining the protective or pathologic role of antibodies in Post-Ebola Syndrome High throughput screening and drug discovery for antagonists of the Ebola VP40 protein assembly Understanding the Impact of Dengue Virus Lineage Persistence on Outbreak Potential Emerging and Re-Emerging Pathogens Research Training Program in DRC (EREP-RTP-DRC) JEAN-JACQUES TAMFUM MUYEMBE-TAMFUM INSTITUT NATIONAL / RECHERCHE BIOMEDICAL Research Project 1: Role of Epigenetic and Transcriptional Mechanisms in the Pathogenesis of Ebola Virus Disease Research Project 2: Role of Posttranscriptional Regulatory Networks in the Pathogenesis of Ebola Virus Disease Research Project 3: Role of Posttranslational Protein Modifications in the Pathogenesis of Ebola Virus Disease West African Center for Emerging Infectious Diseases Spillover of Ebola and other filoviruses at ecological boundaries Development of Optofluidic Resonators for Filoviral Detection UNIVERSITY OF CALIFORNIA-IRVINE “Contributions of Ebola and Marburg virus VP30 and VP24 proteins to viral RNA synthesis, assembly and egress” Antibody and Reagent Development Core Real-time tracking of virus evolution for vaccine strain selection and epidemiological investigation The Protective and Pathologic Features of the EVD Survivor Immune System Cryo-EM of Helical Protein and Nucleoprotein Polymers at Near Atomic Resolution Cryo-EM of Helical Protein and Nucleoprotein Polymers at Near Atomic Resolution Tolerance and resistance responses of African bats to viral antigens: Immunological tradeoffs in zoonotic reservoir hosts.

Mali-Guinea Emerging Infectious Disease Research Training Program (Mali-Guinea EID-RTP) UNIV OF SCIENCES, TECH & TECH OF BAMAKO Improving survival from Burkholderia pseudomallei and other pathogenic intracellular bacteria BOLDER BIOTECHNOLOGY, INC. Center for Viral Systems Biology (CViSB) SCRIPPS RESEARCH INSTITUTE, THE SCRIPPS RESEARCH INSTITUTE, THE SCRIPPS RESEARCH INSTITUTE, THE Defining how ubiquitination of Ebola viral proteins affect host-viral dynamics Insight into the Ebola virus glycoprotein fusion mechanism gleaned from the 2013-2016 epidemic GP-A82V variant Determining Tropism and Mechanisms of Ebola Virus Entry in Placental Tissues Functional genomic characterization of diverse bat innate immune mechanisms Preclinical development of a Nipah Virus inhibitor COLLABORATIONS PHARMACEUTICALS, INC. “PA21259, SBIR, Phase I, Aptamer-upconverting nanocrystal conjugate lateral flow assay for immediate Ebola virus detection” A Fully Integrated Point-of-Care Test for Ebola A modular platform for infectious disease surveillance at point-of-need.

Defining the effect of Plasmodium infection on Ebola virus vaccine efficacy Monoclonal Antibody Cocktail for Treatment of Marburg Virus Disease Elucidating mechanisms of interferon gamma that protect against Ebola virus infection High throughput screening and drug discovery for antagonists of the Ebola VP40 protein assembly Learning from the Ebola success: Can a mAb also save lives after yellow fever infection?

Antibody and Reagent Development Core “Contributions of Ebola and Marburg virus VP30 and VP24 proteins to viral RNA synthesis, assembly and egress” Development of Optofluidic Resonators for Filoviral Detection UNIVERSITY OF CALIFORNIA-IRVINE Optimizing Ridaifen-B analogs as potential therapeutics for Ebola viruses DANIEL DESIRE TSHALA-KATUMBAY OREGON HEALTH & SCIENCE UNIVERSITY “Development of Host- Oriented Therapeutics Targeting Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2),” FOX CHASE CHEMICAL DIVERSITY CENTER, INC Pathogenesis of Uveitis in Ebola Virus Disease Survivors Mechanisms of Ebola virus-mediated inflammatory activation linked to pathogenesis Defining the protective or pathologic role of antibodies in Post-Ebola Syndrome Specific and Broadly Active Monoclonal Antibody Therapeutics Against The Filoviruses Consortium for Immunotherapeutics against Emerging Viral Threats Cryo-EM of Helical Protein and Nucleoprotein Polymers at Near Atomic Resolution Cryo-EM of Helical Protein and Nucleoprotein Polymers at Near Atomic Resolution Dissecting the mechanisms of intestinal epithelial injury by Ebola virus using iPSC-derived intestinal organoids Real-time tracking of virus evolution for vaccine strain selection and epidemiological investigation The Protective and Pathologic Features of the EVD Survivor Immune System Partnership for Research in Emerginig Viral Infections-Sierra Leone (PREVSL) Training in Clinical and Epidemiological Research for Liberia (TRACER) UNIVERSITY OF CALIFORNIA, SAN FRANCISCO Rationally Designed Pan-Ebolavirus Vaccine Role of the Glycocalyx and Spike-Like Proteins in Virus-Cell Adhesion XIAOHUI ZHANG ; ANAND JAGOTA ; Novel VP30-host Interactions that Negatively Regulate Ebola Virus Infection Tolerance and resistance responses of African bats to viral antigens: Immunological tradeoffs in zoonotic reservoir hosts.

Core A: Administrative Core Molecular Mechanisms of the Dysregulated Immune Response to Ebola Virus Research Project 3: Role of Posttranslational Protein Modifications in the Pathogenesis of Ebola Virus Disease Research Project 2: Role of Posttranscriptional Regulatory Networks in the Pathogenesis of Ebola Virus Disease Research Project 1: Role of Epigenetic and Transcriptional Mechanisms in the Pathogenesis of Ebola Virus Disease Novel VP30-host Interactions that Negatively Regulate Ebola Virus Infection Mali-Guinea Emerging Infectious Disease Research Training Program (Mali-Guinea EID-RTP) UNIV OF SCIENCES, TECH & TECH OF BAMAKO Preclinical development of a vaccine for Nipah virus SCRIPPS RESEARCH INSTITUTE, THE SCRIPPS RESEARCH INSTITUTE, THE Center for Viral Systems Biology (CViSB) SCRIPPS RESEARCH INSTITUTE, THE Merging machine learning and mechanistic models to improve prediction and inference in emerging epidemics Insight into the Ebola virus glycoprotein fusion mechanism gleaned from the 2013-2016 epidemic GP-A82V variant Determining Tropism and Mechanisms of Ebola Virus Entry in Placental Tissues Functional genomic characterization of diverse bat innate immune mechanisms Merging machine learning and mechanistic models to improve prediction and inference in emerging epidemics A Biomedical Mass Spectrometry Resource: Ongoing Driving Biomedical Projects Optimizing Ridaifen-B analogs as potential therapeutics for Ebola viruses Genomic Characterization and Surveillance of Microbial Threats in West Africa “Ebola modeling: behavior, asymptomatic infection, and contacts” UNIVERSITY OF CALIFORNIA, SAN FRANCISCO West African Emerging Infectious Disease Research Center (WA-EIDRC) SCRIPPS RESEARCH INSTITUTE, THE A modular platform for infectious disease surveillance at point-of-need.

Elucidating mechanisms of interferon gamma that protect against Ebola virus infection “SBIR, Phase I (R43): Ultrasensitive Lateral Flow Assays Enabled by Fluorescent Nanodiamond Labels” ADAMAS NANOTECHNOLOGIES, INC. “Development of Host- Oriented Therapeutics Targeting Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2),” FOX CHASE CHEMICAL DIVERSITY CENTER, INC Real-time tracking of virus evolution for vaccine strain selection and epidemiological investigation Understanding the epidemiology and natural history of unrecognized Ebola virus infection UNIVERSITY OF CALIFORNIA, SAN FRANCISCO A Fully Integrated Point-of-Care Test for Ebola Hybrid Kinetic Monte Carlo Methods with Applications in Biofabrication and Epidemics Mechanisms of Ebola virus-mediated inflammatory activation linked to pathogenesis Antiviral Lead Identification to Treat Filovirus Infections DANIEL DESIRE TSHALA-KATUMBAY OREGON HEALTH & SCIENCE UNIVERSITY Learning from the Ebola success: Can a mAb also save lives after yellow fever infection?

Development of Optofluidic Resonators for Filoviral Detection Pathogenesis of Uveitis in Ebola Virus Disease Survivors Design and Analysis of Vaccine Trials for Emerging Infectious Disease Threats Dissecting the mechanisms of intestinal epithelial injury by Ebola virus using iPSC-derived intestinal organoids “Long term stress and impairment in children and youth after an acute infectious disease outbreak: A longitudinal study of the social, familial and individual effects of Ebola viral disease (EVD)” Development of Antivirals against Filovirus Replication Project 1: Small Molecule Entry Inhibitors of Pandemic Viruses Cryo-EM of Helical Protein and Nucleoprotein Polymers at Near Atomic Resolution Consortium for Immunotherapeutics against Emerging Viral Threats Specific and Broadly Active Monoclonal Antibody Therapeutics Against The Filoviruses Training in Clinical and Epidemiological Research for Liberia (TRACER) UNIVERSITY OF CALIFORNIA, SAN FRANCISCO Regulation of Ebola virus replication by the host ubiquitin system Partnership for Research in Emerging Viral Infections-Sierra Leone (PREVSL) Mali-Guinea Emerging Infectious Disease Research Training Program (Mali-Guinea EID-RTP) UNIV OF SCIENCES, TECH & TECH OF BAMAKO Scalable Inference in Statistical Models of Viral Evolution and Human Health Molecular Mechanisms of the Dysregulated Immune Response to Ebola Virus Research Project 1: Role of Epigenetic and Transcriptional Mechanisms in the Pathogenesis of Ebola Virus Disease Core A: Administrative Core Research Project 3: Role of Posttranslational Protein Modifications in the Pathogenesis of Ebola Virus Disease Research Project 2: Role of Posttranscriptional Regulatory Networks in the Pathogenesis of Ebola Virus Disease Intrinsically-enhanced Ebola and Marburg virus like particles for increased potency and immune memory Ebola virus infection of the female reproductive system Spillover of Ebola and other filoviruses at ecological boundaries Consortium for Viral Systems Biology (CViSB) Systems biology of Ebola virus and Lassa virus determinants of infection outcome Systems-level identification of host determinants of patient outcomes in Lassa fever and Ebola Consortium for Viral Systems Biology Technology Core Novel VP30-host Interactions that Negatively Regulate Ebola Virus Infection Tolerance and resistance responses of African bats to viral antigens: Immunological tradeoffs in zoonotic reservoir hosts.

Tunneling nanotubes as an alternate route of Ebola virus dissemination Structure-Based Design of Peptide Entry Inhibitors against Ebola Virus Infection Small Molecule Inhibitors of Ebola Virus Polymerase Function Molecular Mechanisms of Viral Entry by Membrane Fusion Insight into the Ebola virus glycoprotein fusion mechanism gleaned from the 2013-2016 epidemic GP-A82V variant Evaluation of ARN-75039 for dual efficacy against both parenteral and aerosolized Lassa virus infection in a guinea pig model.

ARISAN THERAPEUTICS, INC. GH19-003, Epidemiology and Immunity to Ebola Virus and Other Emerging Viral Infections in Liberia Pathogenesis of Uveitis in Ebola Virus Disease Survivors OREGON HEALTH & SCIENCE UNIVERSITY Consortium for Viral Systems Biology (CViSB) West African Center for Emerging Infectious Diseases Project 1 Viral Genomics: surveillance, epidemiology, host response, and viral immunogenicity Project 1 Viral Genomics: surveillance, epidemiology, host response, and viral immunogenicity Ebola modeling: behavior, asymptomatic infection, and contacts UNIVERSITY OF CALIFORNIA, SAN FRANCISCO Project 1 Viral Genomics: surveillance, epidemiology, host response, and viral immunogenicity Partnership for Research in Emerging Viral Infections-Sierra Leone (PREVSL) Genomic Characterization and Surveillance of Microbial Threats in West Africa Prospectively characterizing the functional and antigenic effects of mutations to viral entry proteins