Paul Calabresi Career Development Award for Clinical Oncology (K12 Clinical Trial Optional)

The Paul Calabresi Career Development Award for Clinical Oncology (K12 Clinical Trial Optional) is a grant from the National Institutes of Health (NIH) that funds career development for clinicians in clinical and translational cancer research. The program aims to increase the number of M. D.

s, D. O. s, Pharm.

D. s, and nurses with Ph. D.

s trained in cancer research by supporting their appointment as scholars on independent or ancillary clinical trials. The award provides up to five years of support and is renewable. It is not intended for laboratory-based research.

Eligible applicants are higher education institutions. At the time of award, the principal investigator must be a U.S. citizen or lawful permanent resident.

Paul Calabresi Career Development Award for Clinical Oncology (K12) The purpose of the Paul Calabresi Career Development Award for Clinical Oncology (PCACO) K12 is to increase the number of clinicians (M. D. s, D.

O. s, Pharm. D.

s, nurses with Ph. D. s or equivalent) trained in clinical and translational cancer research, and to promote their career development as cancer researchers.

General Award Information Frequently Asked Questions Do you have questions about your NCI application or award for training in cancer research or education? Make the NCI Frequently Asked Questions your first stop to getting answers!

The NCI K12 allows appointment of Scholars proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial to an existing trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development. The PCACO is not intended to train scientists for laboratory-based research.

The PCACO provides up to 5 years of support and is renewable. Note: The details on this page are for informational purposes only. Please read and follow all requirements and instructions in the notice of funding opportunity (NOFO) and the Table of IC-Specific Information linked therein before applying for an award.

Application review information is described in the funding opportunity. If you have any questions before submitting your application, please contact the relevant NCI program staff listed at the end of this page. For more complete information, reference the Program Announcement PAR-22-136 (K12 Clinical Trial Optional) and/or contact the program staff.

Citizenship At the time of the award, the PI must be: a citizen of the United States or a non-citizen national or must have been lawfully admitted to the United States for permanent residence (i.e., in possession of a currently valid Alien Registration Receipt Card (1-151 or 1-551), or other legal verification of such status).

Career Stage Established Investigators (Associate and Full Professors) Expected to have ongoing R01 and/or R01-like cancer- focused grant support (for the K12 Program, R01 and/or R01-like awards are grants or contracts of at least 3 years and $150,000 a year in direct costs, including those supporting clinical trials) Career Stage Researchers representing a range of disciplines and perspectives are encouraged to participate as mentors.

Expected to have independent R01 and/or R01-like cancer-related research support (for the K12 Program, R01 and/or R01-like awards are grants or contracts of at least 3 years and $150,000 a year in direct costs, including those supporting clinical trials) Citizenship At the time of the award, the scholar must be: a citizen of the United States or must have been lawfully admitted to the United States for permanent residence (i.e., in possession of a currently valid Alien Registration Receipt Card (1-151 or 1-551), or other legal verification of such status).

Career Stage Clinician-scientist Scholars must be: Physicians holding M. D. or D.

O. degrees Nurses with a Ph. D.

or equivalent degree Scholars still in residency training are not eligible. Commitment Scholars must commit a minimum of 9 calendar months (75% of full-time professional effort) to research and career development.

NCI will allow surgeon-scientists with active surgical duties to request less than 9 person-months (75%) Full-time professional effort under a K12 career development award for the specific purpose of maintaining specialty clinical competency. Scholars may not request less than 6 person-months (50%) full-time professional effort devoted to research and career development activities.

Scholars must provide a justification clearly stating the reason(s) for the reduced amount of effort. Scholars who have U.S. Veterans' Administration (VA) appointments may not consider part of the VA effort toward satisfying the "full-time" requirement at the applicant institution.

Duration of Support for each Scholar 2 to 4 years of support K12 Program Allowable Costs Direct Cost Limits All applications must not exceed $750,000 for direct costs per year. The first year's direct costs budget is capped at $50,000. This first year is for advertising and recruitment of Scholars, Advisory Board(s) recruitment and meeting, curriculum planning and development, and development of individual Scholar's curricula.

Personnel Support Up to 1. 2 person months total effort per annum may be allocated for all PDs/PIs of the K12 program to partially offset their salaries and associated fringe benefit costs, depending on commitment of effort ( NOT-OD-24-057: Guidance on Salary Limitation for Grants and Cooperative Agreements FY 2024 ) Salary requests for the Program Faculty/Mentors are not allowed.

In years other than year 1 of a new award, if applicable and justified, up to $26,000 per year may be requested to defray the costs of a consultant, Program Administrator, and/or program assistant with responsibilities directly associated with the institutional career development program; salaries must be commensurate with institutional policy for similar positions and specifically identified and justified.

Travel for key persons and Advisory Committee members must be justified as specifically required by the proposed program and must not duplicate items generally available for similar programs at the applicant institution.

Travel funds at the rate of $1,500 per person will be provided to defray the travel costs to attend a K-12 community conference (a regular conference voluntarily organized by an institute(s) with an NCI K12 award for the purpose of gathering K12 Scholars and Mentors for exchange of knowledge, career development and networking). https://grants. nih.

gov/grants/guide/notice-files/NOT-CA-20-088. html F&A Costs/Indirect Costs 8% Financial Support for Each K12 Fellow Salary Up to $100K/year + fringe benefits Research Development Support Up to $30K/year Applications must be submitted electronically. Applicants must follow the SF424 (R&R) Application Guide , as well as any program-specific instructions noted in Section IV.

of the Program Announcement. When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions in Program Announcement. Applications that do not comply with these instructions may be delayed or not be accepted for review.

For assistance with application submission, please see the Frequently Asked Questions and/or contact eRA Commons Help Desk/Grant. gov contact Center . Application Receipt Dates and Review Schedule Please refer to the Program Announcement for application due dates.

Applications are due by 5 pm local time. When a standard submission date falls on a weekend or Federal holiday , the application deadline is automatically extended to the next business day. Note : Start dates are determined by the availability of NCI funds and may not occur until well after the earliest possible start date.

Review and Selection Process The Center for Scientific Review (CSR) reviews applications for completeness and conformance to all eligibility requirements and special provisions and requirements. Incomplete applications will be returned to the applicant without further consideration. Peer review panel to be determined by CSR.

Before an award is made, the National Cancer Advisory Board (NCAB) conducts a second level of review and ensures that an application meets the broad program needs and priorities of the NCI and the National Cancer Program. For review criteria for the K12 grant mechanism, see the Section V. Application Review Criteria section of the Program Announcement.

This is an NCI-specific Program Announcement. For all of the policies governing this award mechanism, refer to the Program Announcement. For required Tables for New and Competing Renewal applications, please see Data tables for use with Institutional Research Training grant applications using the SF424 (R&R).

Special Institutional Statement Regarding Human Subjects Research Under K12 Support The National Cancer Institute (NCI) Paul Calabresi Career Development Award for Clinical Oncology (K12) must be in compliance with all NIH/NCI policies pertaining to the use of human subjects. These policies apply to all research involving human subjects, not just clinical trials.

The K12 is a training and career development grant in which candidate positions are filled at the discretion of the institution, and assignment of candidate positions is generally not known at the time of application or at the time of an award.

Due to this uncertainty, the word "Indefinite" should be placed in the box for IRB review date on the face page of the application, and the applicant institution must provide in the submitted grant application a Special Statement on Human Subjects Research.

Paul Calabresi Career Development Award for Clinical Oncology Funding Opportunity: PAR-22-136 (K12 Clinical Trial Optional) Worta McCaskill-Stevens Career Development Award for Community Oncology and Prevention Research (K12) Current List of K12 Awards Overview of the Grant Process NCI Resources for Researchers NIH Grants Policy Statement (GPS) - see section 12 For additional information regarding policies and/or guidance in preparing an application for the K12 Award, contact: Email: NCIK12Calabresi@nih.

gov For assistance with xTrain, contact: xTrain Program Specialist For technical issues with xTrain, contact the eRA Service Desk For information regarding fiscal and/or budget issues, contact: Office of Grants Administration Email: NCIFinancialContact@nih. gov For information regarding referral issues, contact: Email: ncirefof@dea. nci.

nih. gov For information regarding review issues, contact: Center for Scientific Review, Division of Receipt & Referral Email: csrdrr@mail. nih.

gov Scientific Review Officer Email: found in your eRA Commons account