Pediatric Critical Care and Trauma Scientist Development Program (K12 Clinical Trial Optional)

Pediatric Critical Care and Trauma Scientist Development Program (K12 Clinical Trial Optional) is sponsored by National Institutes of Health (NIH). This program supports the development of pediatric critical care and trauma scientists.

Expired RFA-HD-24-001: Pediatric Critical Care and Trauma Scientist Development Program (K12 Clinical Trial Optional) This notice has expired. Check the NIH Guide for active opportunities and notices. Department of Health and Human Services Part 1.

Overview Information Participating Organization(s) National Institutes of Health ( NIH ) Components of Participating Organizations Eunice Kennedy Shriver National Institute of Child Health and Human Development ( NICHD ) Funding Opportunity Title Pediatric Critical Care and Trauma Scientist Development Program (K12 Clinical Trial Optional) K12 Physician Scientist Award Program (PSA) Funding Opportunity Announcement (FOA) Number Companion Funding Opportunity See Section III.

3. Additional Information on Eligibility. Assistance Listing Number(s) Funding Opportunity Purpose This Funding Opportunity Announcement (FOA) invites applications to support a national program of mentored career development and training in research for junior faculty in pediatric critical care medicine and pediatric trauma surgery.

The Pediatric Critical Care and Trauma Scientist Development Program (PCCTSDP) was developed to fuel the pipeline of well-trained investigators and advance research in the clinically demanding fields of pediatric critical care and trauma surgery.

This Funding Opportunity Announcement (FOA) allows appointment of Scholars (K12)] proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

Open Date (Earliest Submission Date) Letter of Intent Due Date(s) Renewal / Resubmission / Revision (as allowed) All applications are due by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Required Application Instructions It is critical that applicants follow the Training (T) Instructions in the SF424 (R&R) Application Guide , except where instructed to do otherwise (in this FOA or in a Notice from the NIH Guide for Grants and Contracts ). Conformance to all requirements (both in the Application Guide and the FOA) is required and strictly enforced.

Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions. Applications that do not comply with these instructions may be delayed or not accepted for review.

Part 1. Overview Information Part 2. Full Text of Announcement Section I.

Funding Opportunity Description Section II. Award Information Section III. Eligibility Information Section IV.

Application and Submission Information Section V. Application Review Information Section VI. Award Administration Information Section VII.

Agency Contacts Section VIII. Other Information Part 2. Full Text of Announcement Section I.

Funding Opportunity Description Purpose and Background Information The overall goal of the NIH Research Career Development programs is to help ensure that a diverse pool of highly trained scientists is available in appropriate scientific disciplines to address the Nation’s biomedical, behavioral, and clinical research needs. More information about Career programs may be found at the NIH Extramural Training Mechanisms website.

This FOA encourages applications from organizations that propose creative and innovative institutional research career development programs in the mission area(s) of the NIH.

The proposed institutional research career development program may complement other, ongoing research training and career development programs at the applicant institution, but the proposed career development experiences must be distinct from those career development programs currently receiving Federal support.

Investigators proposing NIH-defined clinical trials may refer to the Research Methods Resources website for information about developing statistical methods and study designs.

Note : This Funding Opportunity Announcement (FOA) allows appointment of Scholars (K12) proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

The purpose of this funding opportunity announcement (FOA) is to invite applications for the program administration and direction of the Pediatric Critical Care and Trauma Scientist Development Program (PCCTSDP), a national program of research career development for physician-scientists specializing in pediatric critical care medicine and trauma surgery.

The goal of the PCCTSDP is to expand the pool of investigators trained to advance research in pediatric critical and trauma care. In doing so, the program aims to stimulate novel research and innovative investigation into the scientific basis of pediatric critical care and trauma practice and the consequences of critical illness and injury for children and their families.

Additionally, it is intended that this program will build upon and expand the community of investigators who network effectively to advance research in these related fields. The program will fund, up to a maximum of 5 years, the administration and infrastructure of one K12 Career Development Program.

Within the framework of the Pediatric Critical Care and Trauma Scientist Development Program's longstanding commitment to excellence, attention must be given to recruiting a diverse group of prospective investigators to seek opportunities in these relatively nascent and clinically-laden fields, including K12 Scholars from groups underrepresented in the biomedical, behavioral and clinical sciences, including individuals from underrepresented racial and ethnic groups individuals with disabilities, individuals from disadvantaged backgrounds, women at the faculty and above level, (see, Notice of NIH's Interest in Diversity, NOT-OD-20-031) and individuals working in Institutional Development Award (IDeA)-eligible states.

Several convergent developments in critical care medicine, as well as in the larger medical, scientific, and national communities, were fundamental to the initial NICHD decision to develop and maintain support of pediatric critical care and trauma career development and research at the junior faculty level.

Although these fields have exhibited substantial growth over the past decade and outcomes have improved, there are little evidence-based data to drive the field and treatments are still often extrapolated from studies involving adult patients. Consequently, there is a vital need for research to best inform the care of critically ill and injured children.

To assure that such work will be pursued, a pipeline of well trained and prepared investigators is needed. However, given the intense clinical and physical demands of critical care and trauma training, the paucity of established research mentors in these fields, and the ever-growing educational and administrative responsibilities, it is challenging to maintain a workforce of committed and well-prepared scientists in these fields.

It is expected that the Scholars supported by this program will emphasize basic, clinical and/or translational research focused on acute, intermediate and longer-term outcomes for critically ill and/or injured children and their families.

The overall purpose and objectives of the program have not changed significantly since the last competitive funding opportunity announcement for this program, although the structure has evolved to enhance function, foster a diverse workforce and optimize opportunity for success of the program .

The overarching goal of the initiative is to stimulate pediatric critical care and trauma research in the basic, translational and clinical sciences that will improve outcomes in children who sustain critical illness and/or injury by enhancing research capacity and infrastructure in the field on a national level.

More specifically, the objectives of the program are to: Develop guidelines for training, didactic interactions, career development, and the responsible conduct of research among junior faculty pediatric critical care and trauma clinicians. Identify and develop a network of diverse , established faculty with a record of research support and productivity who can serve as potential mentors and secondary resources for Scholars.

Assure that primary consideration be given to candidates whose research interests will lead to expanded knowledge that ultimately will improve outcomes and quality of life for critically ill and/or injured children. Coordinate with participating institutions and departments to ensure that Scholars receive the appropriate research support, non-clinical time protection, and opportunities for advancement.

Recruit, identify and select those individuals who would most benefit from participation in this program and are most likely to develop independent careers in research. Provide special opportunities for research presentations, professional advancement, career counseling and networking.

Through recruitment efforts , encourage individuals from racial/ethnic groups underrepresented in biomedical sciences and persons with disabilities to seek opportunities to participate as Scholars, mentors, or in other resource positions. Provide a framework for early research career awareness and preparation for scholars from diverse backgrounds , including those from underrepresented racial and ethnic groups .

Provide periodic and systematic evaluations of the PCCTSDP as a whole. Every facet of the United States scientific research enterprise from basic laboratory research to clinical and translational research to policy formation requires superior intellect, creativity, and a wide range of skill sets and viewpoints.

NIH’s ability to help ensure that the nation remains a global leader in scientific discovery and innovation is dependent upon a pool of highly talented scientists from diverse backgrounds who will help to further NIH's mission. Research shows that diverse teams working together and capitalizing on innovative ideas and distinct perspectives outperform homogenous teams.

Scientists and trainees from diverse backgrounds and life experiences bring different perspectives, creativity, and individual enterprise to address complex scientific problems.

There are many benefits that flow from a diverse NIH-supported scientific workforce, including: fostering scientific innovation, enhancing global competitiveness, contributing to robust learning environments, improving the quality of the researchers, advancing the likelihood that underserved or health disparity populations participate in, and benefit from health research, and enhancing public trust.

See, Notice of NIH's Interest in Diversity, NOT-OD-20-031. Attention must be given to recruiting prospective Scholars and established faculty from diverse backgrounds, including groups that have been identified as underrepresented in the biomedical sciences.

Note : In addition to basic, translational and clinical research, this Funding Opportunity Announcement (FOA) allows appointment of Scholars (K12) who will 1) serve as the lead investigator of an independent clinical trial; 2) propose an ancillary clinical trial; or 3) propose to gain research experience in a clinical trial led by another investigator. See Section VIII. Other Information for award authorities and regulations.

Section II. Award Information Grant: A support mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity. Application Types Allowed The OER Glossary and the SF424 (R&R) Application Guide provide details on these application types.

Only those application types listed here are allowed for this FOA. Optional: Accepting applications that either propose or do not propose clinical trial(s). Need help determining whether you are doing a clinical trial?

Funds Available and Anticipated Number of Awards NICHD intends to commit $847,800 in FY 2024 to fund one award. Application budgets are limited to $785,000 in direct costs and must reflect the actual needs of the proposed project. The maximum project period is 5 years.

Other Award Budget Information Individuals designing, directing, and implementing the career development program may request salary and fringe benefits appropriate for the person months devoted to the program. Salaries requested may not exceed the levels commensurate with the institution's policy for similar positions and may not exceed the congressionally mandated cap.

If mentoring interactions and other activities with scholars are considered a regular part of an individual's academic duties, then mentoring and other interactions with scholars are non-reimbursable from grant funds. Salary support for individuals involved in program administration and management must be substantially justified.

Up to $25,000 may be requested for all faculty who are involved in designing, directing, and administering the K12 program. This may include the PD(s)/PI(s), Training Director, and/or Recruiting Officer, as appropriate to the proposed program. The Cost limit applies to all faculty salaries combined.

Up to $25,000 per year may be requested for administrative, clerical, or other staff with responsibilities directly associated with the institutional career development program. The cost limit applies to all staff salaries combined.

Items that may NOT be supported with K12 grant funds include: Salaries and fringe benefits for program mentors; Salary and support for central institutional administrative personnel (e.g. budget officers, grant assistants, and building maintenance personnel), which are usually paid from institutional overhead charges; Salary and support for administrative activities such as institutional public relations or health and educational services.

Scholars are those individuals who benefit from the proposed activities and experiences involved in the career development program. Scholar costs must be justified as specifically required for the proposed career development program and based on institutional policies for salaries paid to individuals in similar positions, regardless of the source of funds. These expenses must be itemized in the proposed budget.

Candidates receive two to three years of intense career development training in a basic or clinical science discipline with an established investigator serving as mentor. The program is designed to support an average of four to five Scholars per year. Salary and Fringe Benefits: Individual Scholars are eligible for up to $100,000 per year for salary and fringe benefits, consistent with the institution's salary scale.

The institution may supplement the NIH salary contribution up to a level that is consistent with the institution's salary scale; however, supplementation may not be from Federal funds unless specifically authorized by the Federal program from which such funds are derived.

The total salary requested must be based on a full-time, 12-month staff appointment and requires scholars to devote a minimum of 9 person-months (75% full-time professional effort) of full-time professional effort to conducting career development and health-related research, with the remaining effort being devoted to activities related to the development of a successful research career.

Research and Career Development Support: For each Scholar, up to $25,000 in additional funds may be budgeted each year to help defray the costs of materials, supplies, technical assistance, and miscellaneous expenses generated by the Scholar's research in the departments and laboratories of the established investigators who serve as mentors.

Grant funds may also be used for tuition, fees, and other educational materials related to career development. Travel funds may be budgeted to attend the annual PCCTSDP functions and other professional meetings. Total awards to individual Scholars need not be equal across these different budget categories.

Items that may NOT be supported with each Scholar's Research and Career Development Support category include: Direct support of the laboratories, travel, and research projects of the investigators serving as mentors beyond those expenses directly attributable to the scholar's project.

Other Program Related Expenses Consultant costs, equipment, supplies, travel for key persons, and other program-related expenses may be included in the proposed budget. These expenses must be justified as specifically required by the proposed program and must not duplicate items generally available at the applicant institution.

Other Program-Related Expenses are limited to $25,000 per year, and may include: Travel expenses for the PD/PI to attend the annual PCCTSDP meetings. Travel expenses for members of the National Advisory Committee to attend the annual PCCTSDP meetings and any other meetings required for the management or evaluation of the K12 program.

Limited travel funds for featured speakers and former Scholars to attend annual PCCTSDP meetings for the purpose of providing career development guidance to those currently in the program.

Items that may NOT be supported with K12 funds include: Support of the mentors' laboratories beyond those expenses directly attributable to the Scholar's project; Travel of the PD/PI, mentors, or other investigators to scientific meetings beyond those associated with the administration of the PCCTSDP; Patient care costs such as inpatient bed days or outpatient visits, except for clinical laboratory analyses essential for the Scholar's research Alterations and renovations.

Indirect Costs (also known as Facilities & Administrative [F&A] Costs) are reimbursed at 8% of modified total direct costs (exclusive of tuition and fees, consortium costs in excess of $25,000, and expenditures for equipment), rather than on the basis of a negotiated rate agreement. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this FOA. Section III.

Eligibility Information Higher Education Institutions Public/State Controlled Institutions of Higher Education Private Institutions of Higher Education The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education: Hispanic-serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISIs) Nonprofits Other Than Institutions of Higher Education Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education) Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education) Indian/Native American Tribal Governments (Federally Recognized) Indian/Native American Tribal Governments (Other than Federally Recognized) U.S. Territory or Possession Native American Tribal Organizations (other than Federally recognized tribal governments) Faith-based or Community-based Organizations Eligible Agencies of the Federal Government U.S. Territory or Possession The sponsoring institution must assure support for the proposed program.

Appropriate institutional commitment to the program includes the provision of adequate staff, facilities, and educational resources that can contribute to the planned program. The applicant institution must have a strong and high quality research program in the area(s) proposed under this FOA and must have the requisite faculty, staff, potential trainees and facilities on site to conduct the proposed institutional program.

In many cases, it is anticipated that the proposed program will complement other ongoing career development programs occurring at the applicant institution and that a substantial number of program faculty will have active research projects in which participating scholars may gain relevant experiences consistent with their research interests and goals. Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Applicant organizations must complete and maintain the following registrations as described in the SF 424 (R&R) Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted.

Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible. The NIH Policy on Late Submission of Grant Applications states that failure to complete registrations in advance of a due date is not a valid reason for a late submission. System for Award Management (SAM) Applicants must complete and maintain an active registration, which requires renewal at least annually .

The renewal process may require as much time as the initial registration. SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code. NATO Commercial and Government Entity (NCAGE) Code Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM.

Unique Entity Identifier (UEI) A UEI is issued as part of the SAM. gov registration process. The same UEI must be used for all registrations, as well as on the grant application.

eRA Commons Once the unique organization identifier is established, organizations can register with eRA Commons in tandem with completing their Grants. gov registration; all registrations must be in place by time of submission. eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an application.

Grants. gov Applicants must have an active SAM registration in order to complete the Grants. gov registration.

Program Directors/Principal Investigators (PD(s)/PI(s)) All PD(s)/PI(s) must have an eRA Commons account. PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role.

Obtaining an eRA Commons account can take up to 2 weeks. Eligible Individuals (Program Director/Principal Investigator) Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research training program as the Training Program Director/Principal Investigator (Training PD/PI) is invited to work with his/her organization to develop an application for support.

Individuals from diverse backgrounds, including underrepresented racial and ethnic groups, individuals with disabilities, and women are always encouraged to apply for NIH support. See, Reminder: Notice of NIH's Encouragement of Applications Supporting Individuals from Underrepresented Ethnic and Racial Groups as well as Individuals with Disabilities, NOT-OD-22-019 .

For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the SF 424 (R&R) Application Guide.

The PD/PI should be an established investigator in the scientific area in which the application is targeted and capable of providing both administrative and scientific leadership to the development and implementation of the proposed program.

The PD/PI will be responsible for the selection and appointment of trainees to the approved research training program, and for the overall direction, management, administration, and evaluation of the program. The PD/PI will be expected to monitor and assess the program and submit all documents and reports as required.

The PD/PI has responsibility for the day-to-day administration of the program and is responsible for appointing members of the Advisory Committee (when applicable), using their recommendations to determine the appropriate allotment of funds.

The PD/PI must be a physician and senior faculty member who is knowledgeable about pediatric critical care and/or pediatric trauma research, has a record of success in laboratory and/or clinical investigation, and has demonstrated skill in mentoring and career development.

The PD/PI, in consultation with the National Advisory Committee, shall define the application process, review candidates, make appointments to qualified individuals, and monitor progress. This FOA does not require cost sharing as defined in the NIH Grants Policy Statement . 3.

Additional Information on Eligibility Only one application per institution (normally identified by having a unique entity identifier (UEI)) is allowed. The NIH will not accept duplicate or highly overlapping applications under review at the same time, per 2. 3.

7. 4 Submission of Resubmission . This means that the NIH will not accept: A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application.

A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application. An application that has substantial overlap with another application pending appeal of initial peer review (see 2. 3.

9. 4 Similar, Essentially Identical, or Identical Applications ). Program faculty should have strong records as researchers, including recent publications and successful competition for research support in the area of the proposed research training program.

Program faculty should also have a record of research training, including successful, former trainees who have established productive careers relevant to the NIH mission. Researchers from diverse backgrounds, including racial and ethnic minorities, persons with disabilities, and women are encouraged to participate as mentors.

Scholars to be supported by the institutional career development program must be at the career level for which the planned program is intended. Scholars are expected to devote a minimum of 9 person-months (75% of full-time professional effort) during the appointment on the K12 award. Scholars must be citizens or noncitizen nationals of the United States or have been lawfully admitted for permanent residence at the time of appointment.

Additional details on citizenship requirements are available in the NIH Grants Policy Statement . Scholars must have received an MD or DO degree, or its equivalent from an accredited domestic or foreign institution and be fully qualified in postgraduate training for pediatric critical illness or trauma practice.

PCCTSDP candidates should be physicians who have completed clinical training and must hold junior faculty positions at institutions with academic and research-intensive programs in pediatric critical care and trauma.

An individual who has previously served as PD/PI of an NIH research grant (e.g., R01, R03, R21, P01), mentored career development award (e.g., K08, K23, K25, K99), subproject of program project (P01), contract (N01), or other equivalent research awards may not be considered as Scholars for the PCCTSDP.

During the period of their appointment, Scholars may not accept or hold any other PHS award that duplicates the provisions of this career award. However, Scholars may remain eligible for other individual mentored career development awards (e.g., K08, K23, K99) at the conclusion of the K12 appointment if additional training is needed to establish research independence.

Combined support through the K12 and other mentored career development award programs must not exceed six years. Prospective Scholars should be encouraged to contact potential mentors prior to formally applying to the PCCTSDP.

Although remaining at the institution of their fellowship is a possibility for Scholars under this award, broadening academic experience through research career development and clinical practice at a different institution should be strongly encouraged. Scholars selected for the program receive two to three years of intense career development training in a basic or clinical science discipline with an established mentor.

Wherever possible, the program should support career development in those areas of research that would have the greatest potential for a positive effect on the emerging field of pediatric critical care and/or trauma medicine and benefit the growing population of children surviving critical illness and injury.

In conjunction with the mentor, the candidate develops a research and career development plan, which will be reviewed annually by the PD/PI and the National Advisory Committee. At least 9 person-months (75 percent of the Scholar's professional effort) must be devoted to research activities supported by the PCCTSDP.

Within the first two years of the program, Scholars should seek outside grant support as they transition to independent researcher positions in their sponsoring pediatric critical care medicine or trauma surgery departments and institutions. It is expected that the departments associated with the PCCTSDP will make a strong commitment to supporting individuals as they develop their independent research careers.

Scholars may engage in brief research activities at another institution if the experience is directly related to the purpose of the award. Periods of leave from the program for greater than two months, whether for professional or personal reasons, require prior written approval from NIH. Section IV.

Application and Submission Information 1. Requesting an Application Package The application forms package specific to this opportunity must be accessed through ASSIST, Grants. gov Workspace or an institutional system-to-system solution.

Links to apply using ASSIST or Grants. gov Workspace are available in Part 1 of this FOA. See your administrative office for instructions if you plan to use an institutional system-to-system solution.

2. Content and Form of Application Submission It is critical that applicants follow the Training (T) Instructions in the SF424 (R&R) Application Guide except where instructed in this funding opportunity announcement to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced.

Applications that are out of compliance with these instructions may be delayed or not accepted for review. Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows IC staff to estimate the potential review workload and plan the review. By the date listed in Part 1.

Overview Information, prospective applicants are asked to submit a letter of intent that includes the following information: Descriptive title of proposed activity Name(s), address(es), and telephone number(s) of the PD(s)/PI(s) Names of other key personnel Participating institution(s) Number and title of this funding opportunity The letter of intent should be sent to: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) All page limitations described in the SF424 Application Guide and the Table of Page Limits must be followed.

Instructions for Application Submission The following section supplements the instructions found in the SF424 (R&R) Application Guide and should be used for preparing an application to this FOA. Substitute the term scholars for all references to trainees in the SF424 (R&R) Application Guide, and substitute the term career development for all references to training in the SF424 (R&R) Application Guide.

All instructions in the SF424 (R&R) Application Guide must be followed. SF424(R&R) Project/Performance Site Locations All instructions in the SF424 (R&R) Application Guide must be followed. SF424 (R&R) Other Project Information All instructions in the SF424 (R&R) Application Guide must be followed.

Substitute the term scholars for all references to trainees in the SF424 (R&R) Application Guide, and substitute the term career development for all references to training in the SF424 (R&R) Application Guide. Project Summary/Abstract. Provide an abstract of the entire application.

Include the objectives, rationale and design of the career development program, as well as key activities in the training plan.

Indicate the plannedduration of appointments, the projected number of scholars including their levels (i.e., predoctoral , postdoctoral , short-term faculty ), and intended trainee/scholar outcomes A plan must be provided for the appointment of an Advisory Committee to monitor progress of the career development program.

The composition, roles, responsibilities, and desired expertise of committee members, frequency of committee meetings, and other relevant information should be included. Describe how the Advisory Committee will function in providing oversight of the development, implementation, and evaluation of recruitment strategies, efforts to sustain the interest of participants, and the evaluation of the overall effectiveness of the program.

A plan for Advisory Committee approval and selection of Scholars should also be included. The proposed Advisory Committee members should not be named in new applications, particularly if they include individuals from outside the institution. However, renewal applications with Advisory Committees should include names of existing external advisors.

Please name your file "Advisory_Committee. pdf". The filename provided for each Other Attachment will be the name used for the bookmark in the electronic application in eRA Commons.

SF424(R&R) Senior/Key Person Profile Expanded Follow all instructions provided in the SF424 (R&R) Application. PHS 398 Cover Page Supplement Follow all instructions provided in the SF424 (R&R) Application. PHS 398 Training Subaward Budget Attachment(s) Follow all instructions provided in the SF424 (R&R) Application Guide.

Research and Related (R&R) Budget Follow all instructions provided in the SF424 (R&R) Application Guide with the following additional modifications: Include all personnel other than the Training PD(s)/PI(s) in the Other Personnel section, including clerical and administrative staff. Also include proposed salary costs for planned scholars. Do not complete the section on Participant/Trainee Support Costs.

PHS 398 Research Training Program Plan The PHS 398 Research Training Program