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Open — NIH accepts Parent SBIR applications on standard receipt dates. The next is January 5, 2027 (then April 5, 2027) under PA-27-100, which replaced PA-24-246.
Historical funding: Up to $323,090 for Phase I; up to $2,153,927 for Phase II
Prior eligibility: U. S. small businesses meeting NIH/SBA eligibility criteria
PHS 2024-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44]) is sponsored by National Institutes of Health (NIH). Parent omnibus solicitation supporting small business R&D in biomedical and behavioral sciences, including assistive technologies and devices for individuals with disabilities such as hand impairments.
PA-27-037 consolidates the Predoctoral to Postdoctoral Transition Award into a single parent announcement across 20 NIH components, with the next deadline December 8, 2026. The eligibility gate is not the science — it is a mandatory change of institution and mentor between the F99 and K00 phases.
Read articleA draft executive order would have put OMB Director Russell Vought on a commission with final say over NIH awards after peer review. Sen. Collins killed it by pointing at a provision Congress already passed. Here is what the episode teaches applicants about the December 11 cliff.
Read articlePA-27-034, PA-27-035 and PA-27-036 replace the institute-specific R25 announcements that research education programs have been built around for a decade. NCI, NIDA and NIGMS have already expired theirs early. Here is what the consolidation actually changes: an 8% indirect cost ceiling, a US-citizens-and-permanent-residents participant rule, a cooperative agreement variant that only exists on one of the three, and no clinical-trial-allowed companion anywhere.
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