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Pilot and Feasibility Grants is sponsored by Pittsburgh Liver Research Center (PLRC). These grants fund new initiatives and/or support new investigators pursuing liver-related research that should lead to R01-type funding or other extramural support. They provide support for investigators to collect preliminary data and/or test a novel hypothesis, with preference given to projects utilizing PLRC Scientific Cores.
Research on hepatic stellate cell liver fibrosis fits within the mission.
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PLRC P&F Grants – Pittsburgh Liver Research Center Pilot & Feasibility Program Director The Pittsburgh Liver Research Center sponsors Pilot and Feasibility grants every year in basic, clinical and translational research that fit the mission of the NIDDK and the PLRC.
Pilot and Feasibility Grants Pilot and Feasibility Grants fund new initiatives and/or support new investigators who are pursuing liver-related research that should lead to R01-type funding or other extramural support at a later date.
These awards are for one year, and they provide support for investigators to collect preliminary data sufficient to support a future extramural grant application for independent research and/or to test a novel hypothesis. They are not intended for large projects by established investigators, or supporting or supplementing the ongoing funded research of an investigator.
Three groups of faculty are eligible to apply for Pilot and Feasibility Grants. Track 1 (N) . Junior investigators without independent grant support (excluding career development awards) seeking to establish independence in the field of liver research.
**This category of applicant will be given preference. ** Track 2 (EN) . Established investigators with independent grant support—past or present—who have not been involved in liver research and who wish to develop new research directions related to the liver.
Track 3 (E) . Established investigators working in liver-related research who wish to begin a new project representing a major departure from their previous NIH-funded research.
PLRC & Community Liver Alliance Cosponsored P&F Award – This award will be available to applicants from underrepresented backgrounds or those who are proposing research addressing liver diseases in underserved communities, healthcare disparities, pathogenesis of sexually dimorphic diseases or other topics with Diversity, Equity and Inclusion (DEI) focus.
2027 Application Details (Available July 2026) PLRC 2026-2027 Pilot and Feasibility Grant Awardees PLRC 2025-2026 Pilot and Feasibility Grant Awardees PLRC 2024-2025 Pilot and Feasibility Grant Awardees PLRC 2023-2024 Pilot and Feasibility Grant Awardees PLRC 2022-2023 Pilot and Feasibility Grant Awardees PLRC 2021-2022 Pilot and Feasibility Grant Awardees PLRC 2020-2021 Pilot and Feasibility Grant Awardees PLRC 2019-2020 Pilot and Feasibility Grant Awardees PLRC 2018-2019 Pilot and Feasibility Grant Awardees PLRC 2017-2018 Pilot and Feasibility Grant Awardees PLRC 2016-2017 Pilot and Feasibility Grant Awardees Coulter Program – PLRC Joint Awards In 2017, Dr. Paulo Fontes and Dr. Chris Hughes received this award for their project entitled, “Whole-organ sonothrombolysis for prevention of ischemic cholangiopathy in DCD liver transplantation.
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According to the current listing, eligibility includes: New Investigators without independent grant support (excluding career development awards) seeking to establish independence in academic liver research; Established Investigators from other areas of biomedical research interested in applying their expertise to liver health or disease research; Established Investigators who will have no independent R01 or R01-equivalent grant support in liver research if they do not secure a substantial grant award in the near future (Bridge support or at-risk PIs). Confirm the full requirements in the official notice before applying.
The published deadline was July 1, 2026, which has passed. Check the official notice for any future application windows before investing time in a proposal.
Pilot and Feasibility Grants is funded by Pittsburgh Liver Research Center (PLRC). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program