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Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Development and Testing of a Multi-use Frameworks Playbook (U01 Clinical Trial Not Allowed) is sponsored by U.S. Department of Health and Human Services; National Institutes of Health - Common Fund. This NIH funding opportunity supports the development and testing of frameworks for multimodal AI tools in healthcare, targeting responsible deployment.
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Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) The PRIMED-AI program seeks to develop innovative, reliable, and cost-effective AI-based tools that integrate clinical imaging with other health data types to enhance personalized medicine for patients with chronic and other health conditions.
PRIMED-AI will be a uniquely synergistic, catalytic, cross‐cutting way of transforming the delivery of precision medicine through the emerging medical AI landscape. The Validation Center opportunity ( RFA-RM-27-014 ) invites applications for a center which will serve as an independent hub for third party verification, validation, and uncertainty quantification of AI-enabled tools developed by the program.
Applications are due: October 2, 2026, by 5:00 PM local time of applicant organization Watch the Validation Center informational webinar The Logistics Center opportunity ( RFA-RM-27-015 ) invites applications for a center which will provide the administrative infrastructure necessary to facilitate and coordinate PRIMED-AI awardee activities to maximize the impact of the program.
The Logistics Center will provide administrative infrastructure through three integrated cores: Administration, Evaluation, and Outreach.
Applications are due: October 2, 2026, by 5:00 PM local time of applicant organization Watch the Logistics Center informational webinar The Development and Testing of a Multi-use Frameworks Playbook opportunity ( RFA-RM-27-011 ) invites applications for projects to develop and test standardized processes that will help organize and support the emerging multimodal-AI field.
Such frameworks will support responsible use of PRIMED-AI models, error mitigation and technical management of data and algorithms, data ontology/linkage, and preparation for regulatory approval.
Applications are due: October 9, 2026, by 5:00 PM local time of applicant organization Watch the Playbook informational webinar The Data-to-Model: An Academic-Industrial Partnership (D2M-AIP) opportunity ( RFA-RM-27-012 ) invites applications for projects that will integrate and harmonize novel multiscale, multimodal data with clinical imaging data as well as develop and test truly novel AI-enabled, image-centered, multimodal clinical decision support tools.
The purpose of this opportunity is to support multi-sector and multi-disciplinary research teams, including investigators from both academia and industry, to create mutually beneficial opportunities for partners in the pre-competitive development stage.
Applications are due: October 19, 2026, by 5:00 PM local time of applicant organization Watch the Data-to-Model Academic Industrial Partnerships informational webinar The Model-to-Clinic (M2C) opportunity ( RFA-RM-27-013 ) invites applications for projects that take clinical decision support tools from validated prototypes to clinical applications.
M2C projects are expected to have high potential for demonstrable, positive impact on patient outcomes and/or healthcare processes. Applications are due: October 19, 2026, by 5:00 PM local time of applicant organization Watch the Model-to-Clinic informational webinar Find answers to Frequently Asked Questions . Contact [email protected] with any additional questions.
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According to the current listing, eligibility includes: Organizations focused on multimodal AI tools in healthcare. Confirm the full requirements in the official notice before applying.
Applications for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Development and Testing of a Multi-use Frameworks Playbook (U01 Clinical Trial Not Allowed) are due October 9, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Development and Testing of a Multi-use Frameworks Playbook (U01 Clinical Trial Not Allowed) is funded by U.S. Department of Health and Human Services; National Institutes of Health - Common Fund. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Validation Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U54 Clinical Trials Not Allowed) is sponsored by U.S. Department of Health and Human Services; National Institutes of Health - Common Fund. This opportunity funds the creation of a Validation Center as part of the PRIMED-AI program.
Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Validation Center (U54 Clinical Trials Not Allowed) is sponsored by U.S. Department of Health and Human Services; National Institutes of Health - Common Fund. The Validation Center will serve as a hub for validating AI-enabled, multimodal CDS tools, supporting reproducibility, interoperability, and clinical translation.
Logistics Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U24 Clinical Trials Not Allowed) is sponsored by National Institutes of Health (NIH). NIH funds a Logistics Center to coordinate the PRIMED-AI program, which develops AI-based clinical decision support tools integrating medical imaging with multimodal health data. This center will manage administration, evaluation, and outreach for a consortium developing these AI tools.
Validation Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U54 Clinical Trials Not Allowed) is sponsored by National Institutes of Health (NIH) - Common Fund. The Validation Center will serve as a hub for validating AI-enabled, multimodal CDS tools, supporting reproducibility, interoperability, and clinical translation in precision medicine.
Logistics Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U24 Clinical Trials Not Allowed) is sponsored by National Institutes of Health (NIH) - Common Fund. This opportunity funds the creation of a Logistics Center to coordinate PRIMED-AI activities, fostering collaboration and standardization in AI-based clinical data integration.
The NIH Common Fund launched PRIMED-AI — Precision Medicine with AI: Integrating Imaging with Multimodal Data — as five coordinated funding opportunities (RFA-RM-27-011 through -015) that build a full pipeline from standards to clinic. Here is how the Playbook, Data-to-Model partnerships, Model-to-Clinic translation, Validation Center, and Logistics Center fit together, what each pays, who is eligible, and how to position before the October 2026 deadlines.
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