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Find similar grantsProactive Health Office: Office-Wide Innovative Solutions Opening for Advanced Research Projects Agency for Health is sponsored by Advanced Research Projects Agency for Health (ARPA-H). Seeks solutions to improve health outcomes by focusing on disease prevention, wellness-promoting behaviors, and early-detection methods.
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Or search similar grants →Extracted from the official opportunity page/RFP to help you evaluate fit faster.
The Advanced Research Projects Agency for Health (ARPA-H) funds high-impact, innovative health research focused on solving complex challenges that can significantly improve health outcomes. Using diverse funding mechanisms, ARPA-H can address the critical challenges that traditional research and private industry cannot. Below are the areas in which ARPA-H is currently soliciting research applications.
You can also learn more about our research focus areas and access submission resources . ARPA-H is committed to fair consideration of all proposals. We recognize the investment of time and resources in applications.
A Program is a collective set of research funded by ARPA-H that focuses on a specific problem or challenge that aligns with the agency’s wider research and development goals. Program opportunities are announced as solicitations called Innovative Solution Openings (ISO), and are open for a limited time. New opportunities are announced throughout the year.
Available Program Opportunities: Hearing Enhancement through ARtificially Intelligent Neurotechnology (HEARING) Intelligent Generator of Research (IGoR) Restorative & health-Enhancing Sleep Time (REST) Systematic Targeting Of MicroPlastics (STOMP) Initiatives are special efforts designed to rapidly move from proposal to funded contracts.
Unlike programs that are driven by a single goal, these targeted investments follow unique funding tracks across a range of topics.
Available Initiative Opportunities: Technology InteGrator and AcceleratoR (TIGAR) Exploratory Topic Brain Repair of Any Injured Neural Structure (BRAINS) Exploratory Topic Small business award opportunities are announced through Small Business Innovation Research (SBIR) awards and Small Business Technology Transfer (STTR) award. Opportunities focus on specific topics based on various ARPA-H needs and are open for a limited time.
Available Small Business Award Opportunities: Mission Office Innovative Solution Openings (ISO) provide a way to seek funds for individual research projects that fall outside the scope of an ARPA-H program or initiative, but that still aligns with an ARPA-H research focus areas. Mission Office ISOs are accepted on a rolling basis.
Before applying to a Mission Office ISO, you should do three things: Familiarize yourself with the ARPA-H research portfolio: Review all research in the ARPA-H Program Portfolio and Initiatives & Sprints to ensure your idea falls outside the scope of existing research. A submission to a Mission Office ISO may be rejected if its within the scope of an existing program or initiative.
Review the solicitations: Read each of the four ISOs linked below to determine which research focus area is the best fit for your idea. Submit a Summary: If you determine your idea is a good fit, you must first submit a Solution Summary (additional guidance provided in the ISO). A Solution Summary is a brief description outlining the key features, goals, and the potential impact of a proposed solution or project.
ARPA-H will provide a response on the viability of, and interest in, the concept based on this information. Note : Summaries are required for all Mission Office ISOs submissions and proposers must receive written feedback from ARPA-H before submitting a full proposal. A proposal submission may be rejected if submitted without having received a response from ARPA-H.
Available Mission Office ISO Opportunities: Learn more about each opportunity and its requirements through the solicitations linked below. Health Science Futures Office ISO (ARPA-H-SOL-24-104): Research that removes scientific and technological limitations that stymie progress towards the health care of the future.
Proactive Health Office ISO (ARPA-H-SOL-24-106): Research that focuses on preventative programs that reduce the likelihood that people become patients. Resilient Systems Office ISO (ARPA-H-SOL-24-103): Research that builds robust and integrated health care systems.
Scalable Solutions Office ISO (ARPA-H-SOL-24-105): Research that addresses challenges to geography, distribution, manufacturing, data and information, and economies to promote equitable solutions.
According to the current listing, eligibility includes: Varies; refer to the official notice for specific eligibility criteria. Confirm the full requirements in the official notice before applying.
Proactive Health Office: Office-Wide Innovative Solutions Opening for Advanced Research Projects Agency for Health is funded by Advanced Research Projects Agency for Health (ARPA-H). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
The Emerging Health Innovators solicitation drops on SAM.gov by the end of September 2026 with 16 named topic areas, an eight-year terminal-degree ceiling, and an eligibility screen that bars national labs, FFRDCs, UARCs, and anyone who has ever led an ARPA prime award. Proposers' Day is October 13. Here is how to read the design.
Read articleARPA-H's 2026 SBIR/STTR BAA opens seven transformative health topics with $600K Phase I and $3.5M Phase II contracts — non-dilutive, milestone-driven money. The July 10 Solution Summary gate decides who ever gets to pitch. Here's how the ARPA-H model differs from NIH and how small health-tech firms actually get through the funnel.
Read articleARPA-H's FY2026 SBIR/STTR solicitation closes its Solution Summary stage July 10, with seven named topics spanning women's health, autoimmune diagnostics, toxin removal, and neurosurgical robotics. Awards run up to $600K for Phase I and $3.5M for Phase II — but they are contracts, not grants, and the four-to-six-page summary is the gate that filters out most applicants. Here is how ARPA-H's model actually works and how to win the first stage.
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