Protein Kinase C in Lung Cancer with Mutant EGFR

Protein Kinase C in Lung Cancer with Mutant EGFR is sponsored by U.S. Department of Veterans Affairs. Investigates the role of protein kinase C in lung cancer with mutant EGFR to inform potential therapeutic targets.

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click column names to sort Neuromodulation for impulsivity and suicidality in Veterans with mildtraumatic brain injury and common co-occurring mental health conditions Expanding Exercise Programming for Veterans Through Telehealth Investigating the Link Between Environmental Dioxin Exposure and HFpEF Risk Among Veterans Lysophosphatidic acid mediates cardiac inflammation and heart failure with preserved ejection fraction the contribution of APOE4 mediated bioenergetic deficits in the cerebrovascular dysfunction in Alzheimer's disease A Multimethod Approach of Social Disconnection in Schizophrenia: Leveraging Digital Phenotyping, Social Network Analyses, and Neuroimaging An EEG Study of Reward Processing and Memory Dysfunction in Schizophrenia Behavioral Activation Delivered via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged from Inpatient Care From Training to Practice: Understanding the Integration of Evidence-Based Psychotherapies for Depression (INTEGRATE) Understanding the Effects of the MISSION Act on VA's Specialty Care Referral Networks Optimizing Specialty Care Access for Veterans with End-Stage Organ Diseases Reducing Fall Risk with the use of Neuromuscular Electrical Stimulation to Maximize the Hip Abductor Muscles in Older Veterans The Development and Implementation of a Peer-Led Diet and Exercise Intervention in Older Urban Dwelling Veterans with Dysmobility Fluoridated scaffolds for the treatment of critical-size bone defects A Pathogenic Role for the Natriuretic Peptide Clearance Receptor in Heart Failure with Preserved Ejection Fraction.

Post-Translational Control of TET Function in Lymphoma BLRD Research Career Scientist Award Application BLRD Research Career Scientist Award Application Combined inhibition of PLK1 and NOTCH for melanoma management Role of sirtuin 6 in melanoma development and progression Dynamics of protein kinase CK2 signaling in prostate cancer pathogenesis Using DNA Repair and Damage as a Tool in Personalizing Aging and Aging Related Diseases Comparative Effectiveness and Safety of Newer and Older Antihyperglycemic Medications Preoptic/Hypothalamic Mechanisms of Sleep-Wake Regulation Preoptic/Hypothalamic Mechanisms of Sleep-Wake Regulation Administration of intratumoral immunocytokine to activate immune rejection of spontaneous canine melanoma Development of new drugs for Toxoplasma by advancing hits from the Global Health Chemical Diversity Library Addressing insufficient positive airway pressure use among older Veterans with obstructive sleep apnea The role of T cell derived cytokines in Helicobacter pylori The role of T cell derived cytokines in Helicobacter pylori and other gastrointestinal infections.

Precision Medicine Approach to Exercise-Based Interventions for Veterans with Knee Osteoarthritis Research Career Scientist Award Treating bone deterioration associated with chronic kidney disease BLRD Research Career Scientist Award Application BLRD Research Career Scientist Award Application BLRD Research Career Scientist Award Application Regulation of Intestinal Bile Acid Absorption in Health and Cholesterol-Related Disorders In situ bioprinting of high-density cell-laden core-shell microgel bioinks enabling cellular condensation for vascularized bone tissue regeneration Multi-tissue type condensations for trachea tissue regeneration via individual cell bioprinting Intense Noise Exposure Impacts Performance of Vestibular Dependent Behaviors Age Related Hearing Loss and Vestibular Dysfunction Efficacy of exercise training in patients with HFpEF Identifying the Role of the IL-6/STAT3 Signaling Pathway in Higher-risk Myelodysplastic Syndrome Antibodies against Oxidized Phospholipids and Osteoporosis A Brief Values Intervention to Support Veterans in Early Buprenorphine Treatment Functional Immune Phenotype and Clinical Outcome of co-Infection with Respiratory Pathogens and SARS-CoV-2 Virus Metabolic Immunomodulation of Wound-Associated Macrophage Functional Plasticity as a Novel Diagnostic Target in Diabetic Veterans Optimizing the Implementation of Whole Health Coaching for Veterans with COPD Neuromuscular electrical stimulation for physical function maintenance during hematopoietic stem cell transplantation Gulf War Veterans' Illness: Symptom Chronicity via Interactions of Diet andLifestyle Risk Factors with the Gut Microbiome Humanized Mouse Model of Gulf War Veterans' Illness Proteolytic Pathways in Venous Thrombus Resolution Role of NK cells in control of HCV infection associated hepatocellular carcinoma Impact of Immune Activation on Cardiovascular and Immune Health in RA Characterization of an anti-Human Papillomavirus (HPV) agent Reducing Burnout among VA PCPs Using Evidence-Based Quality Improvement Modulating cortical inhibitory networks to improve stroke recovery PAtient-centered mUltidiSciplinary care for vEterans undergoing surgery (PAUSE): a hybrid 1 clinical effectiveness-implementation intervention trial Validation of recombinant truncated Tamm-Horsfall protein as a therapeutic tool for kidney injury The immunomodulatory function of Tamm-Horsfall protein in acute kidney injury Telehealth CBT to address social isolation in Veterans with chronic pain Telehealth CBT to increase engagement in pain treatment among Veterans using prescription opioids Molecular mechanisms of posttranscriptional gene regulation in asthmatic airway inflammation Risk Factors for Chronic Memory Problems after Traumatic Brain Injury The terminal steps of cortisol and aldosterone biosynthesis Cognitive rehabilitation to improve functioning in Veterans following COVID-19 Charleston Health Equity and Rural Outreach Innovation Center (HEROIC) Optimizing Transitions for Dual-Use Veterans Living with Dementia followingHospitalization in the Community Cannabidiol as an Adjunctive to Prolonged Exposure for the Treatment of PTSD Functional and Cognitive Rehabilitation of Hoarding Disorder Regulation of Detrusor Overactivity by Cellular Stress in Bladder Ischemia BLR&D Research Career Scientist Award Application Automated Surveillance for Veteran Cardiac Rehabilitation Utilization Development of a Tailored Intervention to Increase Veteran Enrollment in Cardiac Rehabilitation Effect of pericyte stimulation on traumatic brain injury pathophysiology Implementation Intervention to Improve Care for Unhealthy Alcohol Use Research Career Scientist Web-Based Provider Training for Concurrent Treatment of PTSD and Substance Use Disorders using Prolonged Exposure (COPEWeb) Imaging Surveillance After Lung Cancer Treatment Central Sleep Apnea: Physiologic Mechanisms to Inform Treatment Enhancing FLT3 inhibitor efficacy in acute myeloid leukemia with FLT3-ITD Virtual Hope Box Enhanced Facilitation in High-Risk Suicidal Veterans Improving the Assessment of Myelin and Axonal Integrity in Early Multiple Sclerosis Pulmonary aging increases MUC5AC in the airway epithelium, increasing the risk of carcinogenesis Exploring the PACT Act and the Role of Priority Groupings in Delivering VHA Care Platelet factors attenuate alveolar injury during severe pneumonia Options for Pain Management using Nonpharmacological Strategies (OPTIONS) BCCMA: Targeting Gut Microbiome in Gastrointestinal and Liver Diseases in US Veterans; CMA4: At the Crossroads of the Gut Microbiome, Cirrhosis, and PTSD Fecal Microbiota Transplant in Veterans with Cirrhosis Validation of a novel drug target to treat RV failure Right Heart Function in Health and Chronic Disease A Pragmatic Trial to Determine the Benefit of Behaviorally Enhanced Exercise Incentives and Corticosteroid Injections in Osteoarthritis of the Knee A remotely - applied behaviorally- designed intervention incorporating gamification, social incentives, and health coaching to improve durability of physical therapy for knee osteoarthritis (ReAKTIV) Driving Performance after Stroke: Impact of Cognition, Lesion Site, and Driver-Assist Features Investigating the role of retinal astrocytes in exercise-induced retinal neuroprotection The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans with COPD, Emotion Distress, and Low Physical Activity Alleviation of chronic TBI through modulation of calcium signaling Calcium signaling mechanism in proximal tubule underlying calcium nephrolithiasis Engineered 3D microfluidic tubular device as multimodal, functional tissue model ERK-Signaling in Microenvironment of Pancreatic cancer: Development of NovelTherapeutic Hypoxia-Responsive Nano-encapsulated ERK inhibitor BLRD Research Career Scientist Award Application Hormonal Intervention Protects Axon-myelin to Promote Functional Recovery in SCI Research Career Scientist for Naren Banik, PhD Mechanisms and Impact of Islet Vascular Inflammation in Diabetes Transcriptional Control of Skeletal Muscle Atrophy Testing the Efficacy of ACT for Life: A Brief Inpatient Intervention to Maximize Recovery and Prevent Future Suicidal Behavior Pathways to Hope: Pilot fMRI Study of OCPD and Suicide Risk in Trauma-Exposed Veterans Identification of Veterans at-risk for Suicide: a Multidisciplinary Approach Prism adaptation treatment (PAT) for right brain stroke rehabilitation A biomarker for personalized care in post-stroke spatial neglect BCCMA:Modulating microbiome-immune axis in the deployment-related chronic disease of veterans;CMA2:Determine the impact of enhanced intestinal mito Fn on mucosal inflammation,metab & microbiome in IBD Modulation of mitochondrial respiration to treat colitis Precision Pharmacogenomic Perioperative Prediction Slowing proteotoxic neurodegeneration by boosting mitochondrial bioenergetics and recruiting a novel class of chaperones BLRD Research Career Scientist Award Application Implementation of shared decision making in rheumatoid arthritis: A stepped wedge, cluster-randomized trial A Balanced Reach Training Platform to Address Balance Disorders in Older and Neurologically Disabled Veterans The role of electrical synapses in neural dynamics involved in sleep/wake and sensory perception Regulatory T Cell Inhibition of Natural Killer Cells in COPD Nuclease mechanisms in acute kidney injury BLRD Research Career Scientist Award Application Center for Maternal & Infant Outcomes Research in Translation (COMFORT): Examining Military Environmental Exposures in a national cohort of women Veterans Enhancing an Intervention for Smokers with Chronic Pain using IVR: A Randomized Clinical Trial of Smoking Cessation Counseling for Veterans Pain Research, Informatics, Multi-morbidities, and Education (PRIME) Center The Role of Vitamin D Deficiency-induced Macrophage Renin Angiotensin System Activation in the Development of Hypertension The Live Long Walk Strong rehabilitation program: What features improve mobility skills?

Reducing Suicide Risk in Older Veterans with Mental Health Disorders using Problem Solving Therapy Contribution of Phosphate to Inflammatory Bone Loss CTBI: Traumatic brain injury-induced inflammation effects on cognitive evaluations and response inhibition: Mechanisms of increased risk for suicidality Improving the Use of Tumor Genetic Testing with Decision Science Multilevel Veteran-centric Intervention to Improve Precision Oncology BLRD Research Career Scientist Award Application for Howard Becker, PhD Role of BDNF in Stress Effects on Ethanol Dependence-Induced Escalated Drinking CSRD Research Career Scientist Award Application MVP062 VA-DOE: Implementation of Natural Language Processing, Predictive Modeling, and Artificial Intelligence Methods and Findings to Improve REACH Vet Suicide Prevention Functional Outcomes of Cannabis Use (FOCUS) in Veterans with Posttraumatic Stress Disorder Plasticity of GABA input to VTA dopamine neurons in opioid use disorders Characteristics and Determinants of Post-COVID Neurocognitive Dysfunction Brief Cognitive Behavioral Therapy for Chronic Pain to Improve Functional Outcomes among Primary Care Veterans VA SHIELD: Air Force Health Study Biorepository Surfactant Protein C Mutations and Interstitial Lung Disease Improving Implementation of Outpatient Goals of Care Conversations for Veterans with Serious Illness Polymorphic L1 transposons as a Genetic Variable Distinguishing Aggressive from Indolent Prostate Cancer Cellular and viral determinants of the persistent HIV reservoir Beliakova-Bethell, Nadejda RR&D Senior Research Career Scientist Award BCCMA: Foundational Research to Act Upon and Resist Conditions Unfavorable to Bone (FRACTURE CURB) BLRD Research Career Scientist Award Application A lipid signaling network through stearoyl Co-A desaturase regulates hepatocellular carcinogenesis through YAP/TAZ activity The Role of Relaxin Signaling in Adipose Tissue Fibrosis and Function Alveolar macrophage dysregulation in the pathogenesis of Gulf War respiratory illness Establishing the Molecular Mechanisms of Reduced Ethanol Drinking in Calcineurin-Mediated Immunosuppression Treated Rodents Applying Mixed Methods to Identify Links between Cannabis Use and Sleep Behaviors with Ramifications for Veterans Clinical Health Outcomes Modeling the Treatment Response of Transcranial Magnetic Stimulation for Depression Vitamin D and Development Origins of Obesity and Insulin Resistance mTOR signaling and regulation of alpha-cell mass and function A Self-Delivery siRNA for Promoting Regenerative Healing in the Eye Enhancing Veteran Community Reintegration Research (ENCORE) BLRD Research Career Scientist Award Application Aging and Innate immune system resilience in TBI Role of Inflammation and Oxidative Stress in Parkinson's Disease BLRD Research Career Scientist Award Application Role of IL-33 in KRAS and STK11 mutant non-small cell lung cancer BCCMA:Foundational Research to Act Upon and Resist Conditions unfavorable to bone (FRACTURECURB):Role of abaloparatide for fracture healing Hearing Aid Effects on Brain and Behavior BLRD Research Career Scientist Award Application Mental Function And Quality Of Life With Chronic Pain Role of Non-pharmacological Pain Treatments in Safe and Effective Opioid Tapering in Chronic Pain Mechanisms driving airway inflammation in chronic lung disease Regulation of Osteoblasts by ACTH and VEGF Controlling FKBP51 for the treatment of PTSD Telehealth Treatment of Veterans with Alcohol Misuse at Risk for Cardiovascular Disease Oxytocin Signaling in the Control of Cardiometabolic Function in Diet-Induced Obesity Family-Centered Co-Design of a Technology-Facilitated Intervention for Family Caregivers of Critical Care Survivors HSR&D Research Career Scientist Award Stand Down-Think Before You Drink: An RCT of a Mobile App for Hazardous Drinking with Peer Phone Support Using Data Analytics and Targeted Whole Health Coaching to Reduce Frequent Utilization of Acute Care among Homeless Veterans TGFβ and Smad Signaling Components in Esophageal Adenocarcinoma BCCMA: Recovery of Aged Muscle After Disuse Atrophy (REMEDY): Targeting energetics and proteostasis in recovery from disuse atrophy Sarcopenia and recovery from Disuse-Induced Atrophy Effects of a Targeted Web-Based Suicide Prevention Intervention on Suicidal Ideation and Self-Directed Violence: A Randomized Controlled Trial in Veterans Development of advanced personalized modular pressure relief seating cushion systems: Testing and user evaluation RR&D Research Career Scientist Award Toward smart personalized electrotherapy for enhanced healing of ischemic wounds Toward translation of flexSTIM: a biomimetic implanted pattern generator for effective long-term pressure injury prevention through automatedweight shifting and enhanced tissue health.

Biomarkers for pressure injury risk following spinal cord injury: Development of a multi-scalar predictive model for personalized preventive health care Vestibulopathy, imbalance and gait disturbances in Parkinson disease Center for Health Optimization and Implementation Research BLRD Research Career Scientist Award Application The Aquaporin-3/Phospholipase D2 Signaling Pathway in Corneal Wound Healing Application of a mobile health platform for assessing cognition and psychiatric symptoms in Veterans Enhancing treatment outcomes among veterans with alcohol use disorder: Clinical and neural markers of adjunctive approach-avoidance training The Continuing Challenge of Carbapenemases in K.

pneumoniae: KPC-2 & NDM-1 VA SHIELD Coordinating Center Oral Metallo-Beta-Lactamase Inhibitors: Exploiting Reaction Mechanisms Natural Killer Cell Subpopulations in COPD Exacerbations tDCS Combined with a Brief Cognitive Intervention to Reduce Perioperative Pain and Opioid Requirements in Veterans Thriving in the Midst of Moral Pain: The Acceptability and Feasibility of Acceptance and Commitment Therapy for Moral Injury (ACT-MI) Among Warzone Veterans The Role of M1 Leg Area in Volitional and Stereotyped Control of the Lower Limb Bridging bench to bedside with aneurotechnology cross-development platform Improving the Evaluation and Management of Penicillin Allergies in VA Community Living Centers Prediction and Prevention of Hypoglycemia in Veterans with Diabetes Preclinical evaluation of efficacy and safety of a new iron chelator therapy in chronic spinal cord injury Feasibility of Using PET Imaging for Detection of Treatment-Induced Changes in Chronic Neuroinflammation Following TBI Gainesville Brain Rehabilitation Research Center (BRRC) Research Career Scientist Award A nurse-led intervention to extend the Veteran HIV treatment cascade for cardiovascular disease prevention (V-EXTRA-CVD) Advancing Measurement of Veteran Function and Independence: Pursuing a Set of Measures Around the Patient Centered Theme of Home Time Posttraumatic Stress Disorder, Accelerated Biological Aging, and Veteran Health Electrical rectal stimulation to promote bowel emptying after spinal cord injury Mechanisms and Therapeutic Role of C-terminus of Cav1.

3 L-type Calcium Channel in the Heart Development of Near Infrared Fluorescence-Guided Surgical Navigation and Tumor Specific Photoimmunotherapy for Improved Outcomes for GI Cancers BCCMA: VA Colorectal Cancer Clinical & Computational Collaborative (VA-5C): NIR-labeled antibodies to target and label colon polyps and cancer for improved diagnosis and surgery Understanding Pathways to Care for Veterans who Screen Positive for PTSD: The PTSD Access To Healthcare (PATH) Study Understanding Community-based Mental Healthcare for Rural Veterans with Military Sexual Trauma CSP #505 - Millennium Cohort Study Insomnia and Physical Function in Older Veterans During and After CLC Rehabilitation Admission Examining ketamine effects on depression, neuroplasticity, and inflammation in Veterans with Parkinson's disease Cellular Mechanisms of Cardiac ECM Structure and Function Resolving the Paradox of Hearing Complaints with a Normal Audiogram: Differential Diagnosis and Perceptual Impacts of Cochlear Deafferentation Promoting De-Implementation of Inappropriate Antimicrobial Use in Cardiac Device Procedures By Expanding Audit and Feedback Operant conditioning of sensory evoked potentials to reduce phantom limb pain Living electrodes for auditory rehabilitation.

Suppression of elevated intracellular Ca2+ as an early intervention to prevent vision loss BLR&D Research Career Scientist Award Application The EMBER Trial for Weight Management Engagement Long-Term Opioid Therapy: Screen to Evaluate and Treat (Opioid-SET) Transcutaneous Vagal Nerve Stimulation in Veterans with Posttraumatic Stress Disorder Non-Invasive Vagal Nerve Stimulation in Veterans with Mild Traumatic Brain Injury (mTBI) Total Brain Diagnostics (TBD): Analyzing the Impact of Functional Symptom and Clinical Measures on Co-Morbid Mental Health Conditions after TBI Thyroid Hormone and Neuronal Protection POC: Pilot Investigation of Ewing Amputation in Veterans with Peripheral Arterial Disease Undergoing Below Knee Amputation Molecular Repair of Diabetic Mesenchymal Stem Cells (dMSC) for Peripheral Arterial Disease Motivational Interviewing to Address Suicidal Ideation: A Randomized Controlled Trial with Suicidal Veterans A Multi-Method Examination of Veteran Crisis Line Emergency Dispatches Reducing Chronic Opioid Use Among Veterans Undergoing Community Care Surgery Using a Transitional Pain Service CSP #2010 - Research for the VA Precision Oncology Program (RePOP) Leg Stretching Using a Controllable Wearable Exoskeleton on Demand for People with Spasticity Lipid hydroperoxides in sarcopenia and muscle wasting: mechanisms and intervention Specification of sleep-wake control neurons in the basal forebrain CSP #2001 - Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics (VA Intrepid) A Feasibility Study of Home-based Exercise for Older Veterans with Serious Mental Illness Mechanisms of systemic dysfunction responsible for exercise intolerance induced by breast cancer, cytotoxic chemotherapy, and endocrine therapy in Veterans Relationships of affect and neuroinflammation with clinical pain in Veterans with Fibromyalgia.

Consequences of social isolation during the COVID-19 pandemic in older adults with and without Alzheimer's disease Understanding uptake of and adherence to clinical practice guidelines for airway disease among patients cared for in the Veterans Health Administration Kidney Tubule Cell Function and Future Risk of Acute Kidney Injury Mechanisms of Impaired Skeletal Muscle Blood Flow and Exercise Intolerance in Veterans with Heart Failure with Preserved Ejection Fraction: Efficacy of Knee Extensor Training Preventing Chronic Post-Surgical Pain and Prolonged Opioid Use: The Perioperative Pain Self-Management Program Improving Post-Acute Care Value for Veterans Implementing a Decision Support Tool to prevent Community-Acquired Pressure injury in Spinal Cord Injury (SCI) in the Spinal Cord Injury Clinic.

The Nursing Data and Research Consortium (NDR Consortium) IL-1-based immunotherapy in HNSCC A Novel Drug Target for Aggressive Prostate Cancer Mitigating Genomic Research Disparities in the Million Veteran Program Role of BET proteins in neuroinflammation in tauopathy Role of hippocampal interneurons in aberrant neurogenesis and epilepsy after traumatic brain injury Enhancing Geriatric Pain Care with Contextual Patient Generated Profiles Impact of Obesity on Brain Immune Response and Cognition Lethal Suicide Methods in Aging Veterans: Associated Profiles, Trajectories, and Transitions Informing Attempts CSRD Research Career Scientist Award Application MicroRNA Regulation of Phospholipid Homeostasis in Alzheimer's Disease Pathogenesis Novel Disease-modifying Small Molecules for Treatment of Alzheimer's Disease” Role of BK Channel in Chronic Kidney Disease Natural killer cells in pulmonary ischemia-reperfusion injury MyPath: A Patient-Centered Web-Based Intervention to Improve Reproductive Planning for Women Veterans Evaluating Veterans' Reproductive Healthcare Access, Quality and Outcomes in a Changing Landscape (EVOLVE) Targeting LRP1 in Neuroinflammation and Neuropathic Pain Immunogenicity of recombinant zoster vaccine in Rheumatoid arthritis patients Field Usability Testing of a robotic wheelchair with passive-active suspension for seat stability in uneven terrains Preventing and Reversing Interstitial Fibrosis in HFpEF Intracellular immunity, cytosolic DNA sensing by cyclic GAMP synthase, and macrophages in ischemic injury and cardiac remodeling Innate immunity and ischemic stroke Senior Research Career Scientist Antimicrobial Coating for Intracortical Microelectrodes Optimizing Advanced Prostate Cancer Care Among US Veterans Prevention of anal cancer in People Living with HIV (PLWH) Non-selective membrane channel blockers for mTBI Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI Design Improvements and Evaluation of a Knee Stress-Relief Powered Exoskeleton for Veterans with Knee Osteoarthritis Recruitment of Cerebellar Circuits to Modulate Cognition, Reward and Avoidance of Threat Recruitment of Cerebellar Circuits with Balance Training for Cognitive Rehabilitation in a Mouse Model of Mild Traumatic Brain Injury Increasing PTSD Treatment Engagement in Women Veterans: Role of CBT for Insomnia Neurofeedback Impact on Chronic Headache, Sleep and Attention Disorders Experienced by Veterans with Mild Traumatic Brain Injury.

Community Care Utilization among Post-9/11 Veterans with Traumatic Brain Injury How nicotine delivered by Electronic Nicotine Delivery Systems (ENDS) affects the lung and its recovery from cigarette smoking Withdrawn: Evaluation of Left Bundle Branch Area Pacing As A Rescue Strategy for Cardiac Resynchronization Therapy Non-response in Patients With Heart Failure: A Randomized Controlled Trial Impact of Icosapent Ethyl on Alzheimers Disease Biomarkers in Preclinical Adults The Tumor Immune Microenvironment in Pancreatic Cancer Chemoresistance Pathologic Signaling Pathways in AML Cells Control of Inflammatory Acidity in Mucosal Inflammation Approaches to Studying Social Motivation in Schizophrenia Redesigning Preventive Care Recommendations for Diverse Populations of Veterans BLR&D Research Career Scientist Award Application BLRD Research Career Scientist Award Application BCCMA: The Role of Sphingolipids in the Induction & Maintenance of Non-Small Cell Lung Cancer by Oncogenic KRAS The role of RNA splicing in non-small cell lung cancer A Novel Peer-Delivered Recovery-Focused Suicide Prevention Intervention for Veterans with Serious Mental Illness Identification of Brain Circuits Underlying Fear and Panic Evaluating the VA Make-or-Buy Decision in Emergency Care Establishing the Therapeutic Efficacy of Alpha-1-Antitrypsin and Enoxaparin Against COVID-19 Impact of anti-anaerobic antibiotics on clinical outcomes and the microbiome in hospitalized Veterans BLRD Research Career Scientist Award Application RECK in Adverse Cardiac Remodeling and Heart Failure Multi-scale MRI Assessment of Bone Quality and Function in a Chronic Rat Spinal Cord Injury Model Planar Cell Polarity Control in Melanoma Metastasis Modulation of VEGF receptors to prevent limbal stem cell transplant rejection T cell subsets in inflammatory bowel disease Regulation of T cell immunity Transcriptional regulation of T cell immunity Military Exposures, Host Genetics and Epigenetics in Cardiometabolic Health in US Veterans and MVP Genetics of Cardiometabolic Diseases in the VA Population BLRD Research Career Scientist Award Application BCCMA: Foundational Research to Act Upon and Resist Conditions Unfavorable to Bone (FRACTURE CURB): Combined long-acting PTH and calcimimetics actions on skeletal anabolism Effects of ADT on motivation and emotion function in prostate cancer patients: longitudinal imaging and prediction CSRD Research Career Scientist Award Application An investigation of the relationship between toxicant exposures during Gulf War deployment and prodromal Parkinson's disease.

CMA: Immune/Inflammatory Priming in Exacerbating Responses to GWVI Stressors: Implications for GWVI Treatments Microbiome targeted oral butyrate therapy in Gulf War multisymptom illness Neurobiological and Psychological Benefits of Exercise in Fibromyalgia and PTSD Strengthening neuro-cognitive skills for success in school, work and beyond Glycolytic signaling of p38gamma in breast cancer Therapeutic targeting of a novel driver of prostate cancer progression.

Serving All Who Have Served: Enhancing Suicide-Related Care Quality for Black, Indigenous, and People of Color Veterans Patient Readiness for Improvement through Motivation, Engagement, and Decision-making for PTSD (PRIMED-PTSD) Targeting mTORC2 in lung squamous cancer BLRD Merit Review Research Career Scientist (RCS) Award (IK6) Novel molecular strategies to promote functional recovery after traumatic brain injury Activation of the RXR/PPARγ axis improves long-term outcomes after ischemic stroke in aged mice BLRD Research Career Scientist Award Application The Role of Pain-Facilitating Circuits in Chronic Pain after Traumatic Brain Injury Novel Mechanisms Underlying the Development of Atherosclerosis Translational application of mouse models of melanoma brain metastases BCCMA: Determinants and early detection of metastasis in melanoma for unmet needs of Veterans with mucosal melanomas affecting the head, neck, and other rare types BLRD Research Career Scientist Award Application Reversing Age-related Bone Loss by Administration of the Matricellular Protein Cyr61/CCN1 BCCMA: Integrating Nutrition and Metabolic Monitors to Mitigate Cardiometabolic Disparities in our Veterans (VA-iMITIGATE) BCCMA: Interplay of Novel Mediators of Vascular Aging Pathologies.

Project 2: Metabolic Regulation of Vascular Function in Diabetes.

BLRD Research Career Scientist Award Renewal Therapeutic Targeting of Mitochondria in Uromodulin-Associated Chronic Kidney Disease Effects of Metformin on Outcomes of Patients with Pre-diabetes and Atherosclerosis CSP #2016 - Adaptive Clinical Trial for Insomnia in Veterans with PTSD CSP #2009 - Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response: The SCEPTER Trial Precision medicine approaches to chronic inflammatory skin disease of older veterans Identification of the neuroinflammatory signature for CTE using single nucleus RNA sequencing HSR&D Research Career Scientist Award CoachToFit: Adapted Weight Loss Intervention for Individuals with Serious Mental Illness Evaluating the Use of Peer Specialists to Deliver Cognitive Behavioral Social Skills Training An Innovative Two-Step Therapeutic Strategy to Maximize the Effect of Stem Cell Therapy for Post-Traumatic Osteoarthritis CSP #2032 - VA CAUSAL INFERENCE ENTERPRISE Hearing Impairment, Strategies and Outcomes in VA Emergency Departments Novel EPO peptide therapy for chronic rmTBI dependent neurodegeneration and neuroinflammation Using Big-Data to Identify & Prevent Transmission of Carbapenem-Resistant Enterobacteriaceae within VHA Role of HADHA in regulating right ventricular mitochondrial structure and energetic function in pulmonary hypertension Targeting Chemoreceptor Control of Breathing during Sleep to Mitigate Opioid-Associated Sleep Disordered Breathing Predictors of Post-COVID Clinical and Cognitive Consequences Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans with Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome) Optimizing Gait Rehabilitation for Veterans with Non-Traumatic Lower Limb Amputation Walking Exercise Sustainability Through Telehealth for Veterans with Lower-Limb Amputation Prediction Tools for Diabetic Retinopathy Among Veterans Using Machine Learning and Large-scale Data Analysis Techniques BCCMA: Targeting Osteoarthritis Pain and Progression: Defining biologic and inflammatory markers associated with rapid progression BLRD Research Career Scientist Award Application Elucidating functions of mammalian SIRT7 deacetylase in aging and disease MR Biomarkers of Inflammation in Knee Osteoarthritis Preventing levodopa induced dyskinesia in Parkinson's Disease with Statins Cardiovascular Risk of Non-Opioid Pain Medications Chung-Nakandakari, Cecilia VA-DoD Long-Term Impact of Military-Relevant Brain Injury Consortium (LIMBIC) Total Brain Diagnostics (TBD): Analyzing the Impact of Physiologic Measures on Symptom Burden and Function Outcomes after TBI The Effect of Exoskeleton-Assisted Walking and Transcutaneous Spinal Cord Stimulation on Measures of Bone Strength in Persons with Spinal Cord Injury SDR: Genomic analysis of blast tube induced TBI in mice BLRD Research Career Scientist Award Application Pain in Gulf War Illness: Mechanisms and Candidate Treatments Traumatic Brain Injury in ParkinsonÂ’s Disease: A Longitudinal Study Traumatic Brain Injury and Endogenous Pain Modulation Autonomic Regulation of the Immunological Response to Limb Injury Aging with a Traumatic Brain Injury: Implications for Balance Deficits and Fall Risk Determining mechanisms of ovotoxicity from per- and polyfluoroalkyl substances Patient Health Experiences: Using Patient Narratives to Improve Tinnitus Rehabilitation Services and Outcomes Analysis of Olfactory Dysfunction for Early Diagnosis of Parkinson's Disease Building a shared decision making implementation strategy for the emerging paradigm of precision cancer screening Identifying the magnitude and impact of pelvic floor disorders in Veterans with lower limb amputation Functional Dissection of the MARK3 GWAS Locus for Bone Mineral Density BLRD Research Career Scientist Award Application Genomic effects of chronic neurotrauma on hearing loss; relationship between hearing loss, TBI, mild cognitive impairment, and dementia Convergence of Endothelin-1 and Androgen Signaling in Prostate Cancer Bone Metastasis Pancreatic islet alpha cell response to insulin resistance and type 2 diabetes The Role of CCL11 in Inflammatory and Sporadic Colorectal Cancer.

Implementing a Clinical-Community Partnered Intervention to Address Food Insecurity Among High-Risk Veterans Whole Exome Sequencing Study of Early-Onset Ischemic Stroke Metabolic Regulation of Mucosal Inflammation BLRD Research Career Scientist Award Application Models of Primary Osteoporosis Screening in Male Veterans Colon-Emeric, Cathleen S.

Genetic Vulnerabilities Exposed by Intrinsic Beta-Lactamase Overexpression in Acinteobacter Baumannii Examining Early Intervention Obstructive Sleep Apnea Treatment on Long-Term Outcomes in Veterans with SUD/PTSD in a Residential Treatment Program Comparative and cost effectiveness of diabetes medications Million Veteran Program (MVP) Provision of high quality telemental health care during COVID-19 and beyond Novel Intervention for TBI-induced Opioid Seeking Post exertion malaise in Gulf War Illenss: Brain autonomic and behavioral interactions Genetic predictors, pathophysiological mechanisms, and functional consequences of post-acute sequelae of SARS-CoV-2: Exercise challenge of gut microbiome and neuroinflammation in PASC CSRD Research Career Scientist Award Application Identifying Effective Treatment for Veterans Unwilling to Quit Smoking Senior Research Career Scientist Rehabilitation Research and Development Center for Wheelchairs and Rehabilitation Engineering The Advancement of a New Variable-Compliance Socket and Frame System forTransradial Amputees to Optimize Socket Fit and Upper Limb Function Platelets and Microvascular Dysfunction in Traumatic Brain Injury "Pathogenesis of Helicobacter pylori Infection" Sphingolipids in the Pathophysiology of Obesity and Diabetes BLRD Research Career Scientist Award Application Improving exercise rehabilitation efficacy and outcomes in Veterans with peripheral artery disease: Targeting oxidative stress and inflammation Supporting Relationships to Reduce Suicide Risk: A Randomized Control Trial of the Brief Relationship Checkup PDE2a inhibition as a therapeutic target for the chronic effects of repetitive mild TBI Identification of genes conferring susceptibility in a preclinical model of PTSD Chronic Lung Disease and COVID-19: Understanding Severity, Recovery and Rehabilitation Needs (LAUREL Study) Immunomodulation and Inflammation Caused by 4th-generation E-cigarettes in the Setting of Asthma Predicting Suicide Risk: The Role of Aggression Role of M1 Cytokines in the Progression of Chronic Kidney Disease Spinal targets to treat persistent bladder pain Multi-site Pilot Trial of Strengths-based Linkage to Alcohol Care (SLAC) for Hazardous Drinkers in Primary Care To explore the potential of UCH-L1 as a novel therapeutic and diagnostic target in heart failure SDR: Genomic analysis of blast tube induced TBI in mice Neuroinflammatory Status as a Driver of Pathophysiology Following Repetitive Traumatic Brain Injury Connexin Hemichannel Blockers to Preserve Muscle Function and Improve Recovery After Neuromuscular Trauma Mathematical Optimization of Surveillance Ages to Intercept colitis-associated Colorectal cancer (MOSAIC) BLR&D Research Career Scientist Award Application Tumor suppressing pathways in renal cancer Senior Research Career Scientist Leveraging the Genetics of carotid stenosis for identifying novel risk factors and therapeutic opportunities HSR Senior Research Career Scientist Award Tissue plasminogen activator for the treatment of glaucoma Microglia-Vascular Interaction in Alteration of Blood-Retinal Barrier in Diabetic Retinopathy Colon cancer nanotherapy targeting STRAP BLRD Research Career Scientist Award Application Pathophysiology of Adult T-cell leukemia/lymphoma Simplified Accessible Vehicle and Robotic wheelchair The Disrupted Care National Project TSH Receptor Autoregulation Restoring the Regulation of a Central Signaling Pathway to Prevent Metastases and Reinstate Tumor Immunity The impact of cholecystokinin on pancreatic beta-cell survival through paracrine and pharmacologic signaling The Role of the Endoplasmic Reticulum Stress Response in Abdominal Aortic Aneurysm Development BLRD Research Career Scientist Award Application Pandemic Acceptance and Commitment Therapy (Pan-ACT): Feasibility and Acceptability of Telehealth Delivery with Older Veterans Addressing Health Equity in Tobacco Cessation Treatment for Historically Underrepresented Veterans Thrombotic Susceptibility in Veterans: Influence of prediabetes EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following Stroke Multisensory augmentation to improve the standing balance of people with chronic stroke Ototoxicity-associated Mutations Following Antiretroviral Exposure A Hybrid Effectiveness-Implementation Multisite Trial of a Dialectical