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The PRIMED-AI Validation Center is a single-award opportunity to build the independent evaluation infrastructure for the entire NIH Common Fund PRIMED-AI program. Its function is to serve as a dedicated hub that verifies, validates and characterizes the AI-enabled, image-based multimodal clinical decision support tools produced by other PRIMED-AI awardees, assessing reliability, reproducibility and generalizability with an eye toward clinical adoption. This is a structurally different proposition from a research grant and applicants should read it that way: the Center is a service and methods organization accountable to a consortium, not a lab pursuing its own scientific agenda. Competitive applicants will need existing capacity in AI model evaluation, access to diverse and independent clinical validation datasets spanning multiple sites and populations, expertise in regulatory science given the Software as a Medical Device framing of the tools being evaluated, and the organizational maturity to run a benchmarking operation on someone else's timeline. Because only one award is expected, this is a winner-take-all competition, and the budget structure is notably front-loaded in an unusual way - $2,000,000 in direct costs in year one rising to as much as $3,200,000 per year thereafter, making this among the largest single awards in the PRIMED-AI portfolio. Foreign organizations and foreign components are not eligible, unlike the program's tool-development announcements. Institutions that intend to submit tool-development applications under RFA-RM-27-012 or RFA-RM-27-013 should think carefully about the independence expectations before also competing for the Validation Center role. The October 2, 2026 deadline is shared with the Logistics Center announcement (RFA-RM-27-015), the program's companion coordinating infrastructure award.

HORIZON-CL5-2026-10-D6-03 funds generative AI applied to cooperative, connected and automated mobility, and it is one of the clearer statements yet of how European transport research intends to absorb large models. The scope targets robust environment perception and decision-making for Level 3 and Level 4 automated vehicle services - explicitly across the edge, on-board, at infrastructure and at back-office - with particular emphasis on vulnerable road user recognition and safety. Beyond perception, the call asks for generative AI including large language models and vision-language models to be used for scenario generation and validation testing, and for tools and guidelines that help developers integrate these technologies into existing CCAM concepts. That validation angle is the strategically interesting part: the hard unsolved problem in automated driving is proving safety across a scenario space too large to drive, and generative scenario synthesis is a direct attack on it. Proposals are expected to address security, fairness and compliance with European standards for connected and automated mobility, so a purely performance-driven proposal without regulatory and assurance work will read as incomplete. The call runs under the CCAM Partnership, which in practice means proposals should align with the partnership's roadmap and that consortia typically include vehicle manufacturers or tier-one suppliers, road operators or infrastructure partners, and research organisations. The HORIZON-CL5-2026-10 call opens on 4 June 2026 with a proposal deadline of 8 October 2026, giving roughly four months from opening - workable but tight for a consortium of this complexity, so partner discussions should begin before the call opens. Applicants should verify the topic budget, type of action and deadline on the official EU Funding and Tenders Portal.

NOTICE: August 4, 2026. Going forward, a $0.09/SBU charge now applies to all proposing to Earth Science (ROSES Appendix A) to use any NASA high-end computing resource. Proposers must account for this in their budget, per the instructions provided in Section 7.3 of ROSES-25 A.1 Earth Science Research Overview. NOTICE: July 28, 2026. A set of slides describing the Application Readiness Levels (ARLs) has been posted under "other documents" on the NSPIRES page for this program element. Text regarding ARLs has been added to a few locations in Section 2 and a row has been added to the Summary Table of Key information in Section 4. New Text is in bold and deleted text is struck through. We anticipate posting a FAQ under "other documents" after the pre-proposal teleconference on August 31, at 1 pm Eastern Time. NOTICE: Amended July 17, 2026. This amendment presents a new program element in ROSES-2025. Proposals are due October 15, 2026. The pre-proposal teleconference will be held on August 31, at 1 pm Eastern Time on a no-advance-reservation, first-to-dial-in basis. Teleconference information will be posted under other documents on the NSPIRES page for this program element approximately 2 weeks after the element release. This new program element solicits a broad range of research and applications including topics from what were previously individual program elements (agriculture, disaster resilience, natural resources, health and air quality, water resources, wildland fire, energy systems, and resilient infrastructure). The S/T/M Section of the anonymized proposals is limited to ten (10) pages, see Section 3.1 of this program element. Proposals submitted to this program will be evaluated using dual-anonymous review. Proposal documents must be prepared according to the guidelines in Section 3.2 and in the associated "Guidelines for Proposers to ROSES DAPR Programs" document under "Other Documents" on the NSPIRES page for this program element. NOTICE: Research security training required starting August 5, 2026. All PIs and any Co-Is that would spend ≥ 10% time on a proposed grants or cooperative agreements must certify they have taken research security training. NASA will be satisfied with the four online research security training modules on the National Science Foundation's (NSF) Research Security Training website at https://www.nsf.gov/research-security/training or the SECURE Center condensed version of the four modules at https://www.secure-center.org/ctm This synopsis is a generic summary that is posted for each of the many individual "program elements" in NASA’s Research Opportunities in Space and Earth Sciences (ROSES) – 2025 solicitation. For specific information on this particular program element download and read the PDF of the text of this program element by going to Tables 2 or 3 of ROSES at https://solicitation.nasaprs.com/ROSES2025table2 and https://solicitation.nasaprs.com/ROSES2025table3, respectively, click the title of the program element of interest, a hypertext link will take you to a page for that particular program element. On that page, on the right side under "Announcement Documents" the link on the bottom will be to the PDF of the text of the call for proposals. For example, if one were interested in the Solar System Science program (NNH25ZDA001N-SCUBED) one would follow the link to the NSPIRES page for that program element and then to read the text of the call one would click on “C.2 Solar System Science (.pdf)” to download the text of the call. If one wanted to set it into the context of the goals, objectives and know the default rules for all elements within Appendix C, the planetary science division, one might download and read “C.1 Planetary Science Research Program Overview (.pdf)” from that same page. While the letters and numbers are different for each element within ROSES (A.10, B.3, etc.) the basic configuration is always the same, e.g., the letter indicates the Science Division (A is Earth Science, B is Heliophysics etc.) and whatever the letter, #1 is always the division overview. In 2025, most program elements will be set up for application via Grants.gov only if requested at least 30 days in advance of the due date. For more on Grants.gov submissions see Section IV(b)v of the ROSES Summary of Solicitation, that may be found at https://solicitation.nasaprs.com/ROSES2025. The National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD) released its annual omnibus Research Announcement (NRA), Research Opportunities in Space and Earth Sciences (ROSES) – 2025 (OMB Approval Number 2700-0092, CFDA Number 43.001) on February 21, 2025. In this case "omnibus" means that this NRA has many individual program elements, each with its own due dates and topics. All together these cover the wide range of basic and applied supporting research and technology supported by SMD. Awards will be made as grants, cooperative agreements, or contracts depending on the nature of the work proposed. However, most extramural research awards deriving from ROSES will be grants, and many program elements of ROSES specifically exclude contracts, because contracts would not be appropriate for the nature of the work solicited. Funded Co-Is at government labs will receive inter- or intra-agency transfers. The typical period of performance for an award is three years, but some programs may allow up to five years and others specify shorter periods. In most cases, organizations of every type, Government and private, for profit and not-for-profit, domestic and foreign (with some caveats), may submit proposals without restriction on teaming arrangements. Tables listing the program elements and due dates (Tables 2 and 3), a table that provides a very top level summary of proposal contents (Table 1), and the full text of the ROSES-2025 "Summary of Solicitation", may all be found NSPIRES at https://solicitation.nasaprs.com/ROSES2025. Frequently asked questions for ROSES are posted at http://science.nasa.gov/researchers/sara/faqs. Questions concerning specific program elements should be directed to the point(s) of contact for that particular element, who may be found either at the end of the individual program element in the summary table of key information or on the web list of topics and points of contact at: http://science.nasa.gov/researchers/sara/program-officers-list. General questions concerning ROSES-2025 may be directed to the office of the SMD Deputy Associate Administrator for Research at sara@nasa.gov. Not all program elements are known at the time of the release of ROSES. To be informed of new program elements or amendments to this NRA, proposers may subscribe to: (1) The SMD mailing lists (by logging in at http://nspires.nasaprs.com and checking the appropriate boxes under "Account Management" and "Email Subscriptions"), (2) The ROSES-2025 blog feed for amendments, clarifications, and corrections to at https://science.nasa.gov/researchers/solicitations/roses-2025/, and (3) The ROSES-2025 due date Google calendars (one for each science division). Instructions are at https://science.nasa.gov/researchers/sara/library-and-useful-links (link from the words due date calendar). Funding Opportunity Number: NNH25ZDA001N-AES. Assistance Listing: 43.001. Funding Instrument: CA,G. Category: ST.