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ActiveU.S. Department of Health and Human Services, Administration for Children and Families (ACF), Administration on Children, Youth and Families (ACYF), Children's Bureau (CB) · 2026

Regional Partnership Grants to Increase the Well-Being of, and to Improve the Permanency Outcomes for, Children and Families Affected By Opioids and Other Substance Abuse

Quick Facts

Agency: U.S. Department of Health and Human Services, Administration for Children and Families (ACF), Administration on Children, Youth and Families (ACYF), Children's Bureau (CB)
Funding: Varies by NOFO (e.g., $10,800,000 total in 2022, up to $600,000 award ceiling)
Deadline: Check Source
Page confirms the program is reauthorized (P.L. 118-258, 2024) but provides no current application deadline or open NOFO.
Status: Active
Eligibility: States, tribal communities, and cross-system collaborative partnerships serving families affected by parental substance use disorders.
Grant Type: Implementation
Geographic Scope: National

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About This Grant

Regional Partnership Grants to Increase the Well-Being of, and to Improve the Permanency Outcomes for, Children and Families Affected By Opioids and Other Substance Abuse is sponsored by U.S. Department of Health and Human Services, Administration for Children and Families (ACF), Administration on Children, Youth and Families (ACYF), Children's Bureau (CB). This opportunity supports mission-aligned projects and measurable outcomes.

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Official Opportunity Details

Extracted from the official opportunity page/RFP to help you evaluate fit faster.

Regional Partnership Grants Program | National Center on Substance Abuse and Child Welfare Regional Partnership Grants Program The Regional Partnership Grants (RPG) Program, administered by the Administration on Children, Youth and Families (ACYF), Children’s Bureau (CB), aims to improve safety, permanency, and well-being outcomes for children affected by parental substance use disorders.

Since 2007, the National Center on Substance Abuse and Child Welfare (NCSACW) has provided programmatic, data-driven assistance to RPG recipients. The program was initially authorized by the Child and Family Services Improvement Act of 2006, (P. L.

109-288) and further supported by the Family Services Improvement and Innovation Act of 2011 (P. L. 112-34), which allocated funds specifically for RPGs.

The Supporting America’s Children and Families Act of 2024 (P. L. 118-258) reauthorized the RPG Program, continuing the provisions of data-driven assistance to better serve families affected by substance use disorders.

Since 2007, Children's Bureau has awarded seven rounds of RPG funding to 127 projects across 40 states, including tribal communities.

Some outcomes as a result of program participation include: Child safety improved significantly (less maltreatment, abuse, and neglect) Children showed reduced behavior problems and better socialization; executive functioning remained stable Fewer removals from the home and increased permanency and reunification for children Substance use disorder treatment saw higher enrollment and completion and reduced high-severity substance use NCSACW provides support to the RPG recipients on various topics to strengthen implementation of selected interventions.

NCSACW support has helped recipients strengthen their efforts in cross-system collaborative practices and policies focusing on program sustainability, workforce development, trauma-informed services, family-centered treatment, and lasting and efficient systems change.

RPG projects promote interagency collaboration and integration of services to enhance the well-being, permanency, and safety of children who are in, or at risk of, out-of-home placements due to parental substance use disorders.

The partnerships implement a range of activities and interventions, including recovery coaching, family-centered services, parenting programs, support for fathers and pregnant and postpartum women, medications for opioid use disorder, in-home parenting support, and other evidence-based practices. RPG projects strive to enhance and expand effective services for children, parents, and families.

Cross-systems collaborative capacity to streamline communities’ and states’ efforts to save resources Program sustainability to ensure outcomes generated through the grant program are integrated into practice Trauma-informed and evidence-based and evidence-informed services to children, parents, and family members to resolve root causes of intergenerational effects of addiction and child abuse or neglect Family-centered substance use and mental health disorder treatment and recovery support services to ensure all members of the families heal and reduce long-term costs to service systems and programs Lasting systems change to institutionalize programs and practices, resulting in reduced costs over time To view a state profile, select a state or territory.

Contact us at NCSACW@cffutures. org to request a profile that is no longer available on the site. To view a state profile, select a state or territory - Select - Alabama ( 1 ) *This site profile is not available.

Alaska ( 3 ) Arizona ( 1 ) *This site profile is not available. Arkansas ( 0 ) *There is not a site in this state. California ( 10 ) *This site profile is not available.

Colorado ( 4 ) Connecticut ( 1 ) Delaware ( 1 ) *This site profile is not available. District of Columbia ( 0 ) *There is not a site in this state. Florida ( 6 ) Georgia ( 4 ) Hawaii ( 0 ) *There is not a site in this state.

Idaho ( 1 ) *This site profile is not available. Illinois ( 7 ) Indiana ( 1 ) *This site profile is not available. Iowa ( 9 ) Kansas ( 3 ) *This site profile is not available.

Kentucky ( 5 ) Louisiana ( 1 ) Maine ( 1 ) *This site profile is not available. Maryland ( 0 ) *There is not a site in this state. Massachusetts ( 3 ) *This site profile is not available.

Michigan ( 0 ) *There is not a site in this state. Minnesota ( 1 ) *This site profile is not available. Mississippi ( 0 ) *There is not a site in this state.

Missouri ( 8 ) Montana ( 3 ) *This site profile is not available. Nebraska ( 1 ) *This site profile is not available. Nevada ( 2 ) *This site profile is not available.

New Hampshire ( 1 ) New Jersey ( 1 ) New Mexico ( 1 ) *This site profile is not available. New York ( 5 ) North Carolina ( 1 ) *This site profile is not available. North Dakota ( 0 ) *There is not a site in this state.

Ohio ( 4 ) *This site profile is not available. Oklahoma ( 6 ) Oregon ( 5 ) *This site profile is not available. Pennsylvania ( 3 ) Puerto Rico ( 0 ) *There is not a site in this state.

Rhode Island ( 1 ) *This site profile is not available. South Carolina ( 0 ) *There is not a site in this state. South Dakota ( 1 ) *This site profile is not available.

Tennessee ( 7 ) Texas ( 3 ) *This site profile is not available. Utah ( 0 ) *There is not a site in this state. Vermont ( 2 ) *This site profile is not available.

Virginia ( 1 ) *This site profile is not available. Washington ( 2 ) *This site profile is not available. West Virgina ( 3 ) Wisconsin ( 3 ) Wyoming ( 0 ) *There is not a site in this state.

Lessons from the Regional Partnership Grants Program: What Works for Families National Center on Substance Abuse and Child Welfare, 2026 This brief distills two decades of learning from the Regional Partnership Grants (RPG) Program to identify the core collaborative View Document (PDF 7.

49 MB) Policy and Practice Resources Lessons from the Regional Partnership Grants Program: What Works for Families National Center on Substance Abuse and Child... , 2026 This brief distills two decades of learning from the Regional Partnership Grants (RPG) Program to identify the core collaborative View Document (PDF 7. 49 MB) Workforce Stability in the Regional Partnership Grants Program: Staff Transition and Succession Planning St...

National Center on Substance Abuse and Child... , 2026 This resource brief is designed to support Regional Partnership Grants (RPG) Program recipients and their cross-system partners View Document (PDF 3. 7 MB) Regional Partnership Grant Program Summary National Center on Substance Abuse and Child...

, 2025 A brief, two-page synopsis of RPG’s background and history. It provides an overview of project collaborative partnerships, program View Document (PDF 380 KB) Regional Partnership Grants Program Round 3 Infographic National Center on Substance Abuse and Child...

, 2025 Offers a snapshot of key insights from the Regional Partnership Grants (RPG) Round 3 cohort – highlighting locations, findings View Document (PDF 468 KB) Building Hope for Families Affected by Substance Use and Mental Health Disorders: A Blueprint for an Effect... National Center on Substance Abuse and Child...

, 2023 This series describes concrete strategies collaboratives can use to enhance the system of care while improving outcomes for families Technical Assistance Brief Series National Center on Substance Abuse and Child...

, 2021 This series has three briefs discussing the importance of relationships and resources, and the results of how using cross-systems data Sustainability Planning Toolkit - Five Steps to Build a Sustainability Plan for Systems Change National Center on Substance Abuse and Child...

, 2021 Provides collaboratives, organizations, and programs with the tools needed for planning and implementing a sustainability approach for View Document (PDF 2. 26 MB) Child Welfare Timeline for SUD Treatment and Other Partners Technical Assistance Brief National Center on Substance Abuse and Child...

, 2020 Presents three key strategies that agencies can use to strengthen collaboration between child welfare and SUD treatment systems while View Document (PDF 1. 08 MB) Referral and Engagement of Parents in Services Technical Assistance Brief National Center on Substance Abuse and Child...

, 2020 This Regional Partnership Grant Technical Assistance Brief presents four key strategies that projects can use to ensure that families View Document (PDF 1. 05 MB) Sustainability Planning for Regional Partnerships Technical Assistance Brief National Center on Substance Abuse and Child... , 2020 Presents detailed steps grantees can take to begin sustainability planning.

Offers a set of questions to begin planning, mobilizing View Document (PDF 758 KB)

Eligibility Requirements

States, tribal communities, and cross-system collaborative partnerships serving families affected by parental substance use disorders.

Frequently Asked Questions

Who can apply for Regional Partnership Grants to Increase the Well-Being of, and to Improve the Permanency Outcomes for, Children and Families Affected By Opioids and Other Substance Abuse?

According to the current listing, eligibility includes: States, tribal communities, and cross-system collaborative partnerships serving families affected by parental substance use disorders. Confirm the full requirements in the official notice before applying.

How much funding does Regional Partnership Grants to Increase the Well-Being of, and to Improve the Permanency Outcomes for, Children and Families Affected By Opioids and Other Substance Abuse offer?

The current listing shows varies by NOFO (e.g., $10,800,000 total in 2022, up to $600,000 award ceiling). Verify award ceilings, matching requirements, and allowable costs in the official notice.

Who funds Regional Partnership Grants to Increase the Well-Being of, and to Improve the Permanency Outcomes for, Children and Families Affected By Opioids and Other Substance Abuse?

Regional Partnership Grants to Increase the Well-Being of, and to Improve the Permanency Outcomes for, Children and Families Affected By Opioids and Other Substance Abuse is funded by U.S. Department of Health and Human Services, Administration for Children and Families (ACF), Administration on Children, Youth and Families (ACYF), Children's Bureau (CB). Verify program details on the funder's official page before applying.

Is Regional Partnership Grants to Increase the Well-Being of, and to Improve the Permanency Outcomes for, Children and Families Affected By Opioids and Other Substance Abuse available nationwide?

Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.

How do I apply for Regional Partnership Grants to Increase the Well-Being of, and to Improve the Permanency Outcomes for, Children and Families Affected By Opioids and Other Substance Abuse?

Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.

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