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S10 Instrumentation Grant Programs (Basic, Shared, High-end Instrumentation) is sponsored by National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP). ORIP's S10 Instrumentation Grant Programs support purchases of state-of-the-art commercially available instruments to enhance research of NIH-funded investigators. These instruments are used on a shared basis, making the programs cost-efficient.
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Or search similar grants →According to the current listing, eligibility includes: Domestic public and private institutions of higher education, and non-profit domestic institutions such as hospitals, health professional schools, and research organizations. An institution must identify three or more Principal Investigators with active NIH research awards who demonstrate a substantial need for the requested instrument. Confirm the full requirements in the official notice before applying.
The current listing shows basic Instrumentation Grant (BIG): $25,000 - $250,000; Shared Instrumentation Grant (SIG): $50,000 - $750,000; High-end Instrumentation Grant (HEI): $750,001 - $2,000,000. Verify award ceilings, matching requirements, and allowable costs in the official notice.
S10 Instrumentation Grant Programs (Basic, Shared, High-end Instrumentation) is funded by National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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Shared Instrumentation Grant (SIG) Program is sponsored by National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP). The SIG program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of expensive, specialized, commercially available instruments or integrated systems. Confocal microscopes are explicitly mentioned as supported instruments. While the primary focus is biomedical research, plant biology projects with strong biomedical relevance or utilizing relevant imaging technologies could potentially apply.
Small Instrumentation Grants Program (S15) is sponsored by National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP) and National Institute of General Medical Sciences (NIGMS). The S15 program provides institutional awards to support the purchase of equipment costing no less than $5,000 and no more than $60,000. This equipment is to be used by one or more recipients of active NIH research grants, enhancing biomedical research.
Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) is sponsored by National Science Foundation (NSF) & National Institutes of Health (NIH). This interagency program supports high-risk, high-reward advances in AI and data science for biomedical and public health research. Projects must cross disciplinary boundaries.
Innovation Grant is a grant from the Delta Dental of Arizona Foundation that funds nonprofit organizations pursuing unique, high-impact projects that improve health and wellness in Arizona communities. This two-year award supports original initiatives with measurable real-world impact, including programs serving underserved and uninsured populations through oral health education, disease prevention, and nutritional access. Projects must demonstrate the potential to make a meaningful difference in the community and stand apart from conventional approaches. Eligible applicants are Arizona-based nonprofit organizations. Awards total $100,000 per recipient over two years. The 2026 application cycle closed October 16, 2025, with recipients notified in late 2025 and funding made available shortly after.
NOT-OD-26-112 released a draft NIH Biosafety Policy for Research Involving Biohazards on August 19, 2026. It would replace the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules, extend IBC jurisdiction from engineered molecules to wild-type agents, toxins and prions, impose 24-hour incident reporting, and make the Biosafety Officer a federally defined role. Here is what actually changes and how to respond before the October 19, 2026 deadline.
Read articleNIH released a draft policy on August 27, 2026 that would require every NIH-supported clinical study to offer participants a plain-language summary of results — clinical trials within one year of completion, all other clinical research by the end of the funding period. It covers observational and behavioral research that ClinicalTrials.gov never touched. Here is the scope, the four requirements nobody has budgeted for, and what to say before the October 26 deadline.
Read articleUSDA and HHS announced Harvest to Hallways on August 24, 2026: $50M in new cafeteria infrastructure funding on top of $20M in Equipment Assistance Grants, up to $25M more in Patrick Leahy Farm to School awards for FY2026, and $30M in HHS nutrition research. Each pot has a different applicant, a different route, and a different timeline. Here is how to position for all three before the notices post.
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