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Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs is sponsored by Advanced Research Projects Agency for Health (ARPA-H). ARPA-H offers SBIR/STTR awards to small businesses for innovative health research and development projects.
While not explicitly focused on 'health literacy plain language,' proposals addressing health communication challenges within broader health innovation could be relevant.
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For Small Businesses | ARPA-H Learn more about the capabilities and services available to all ARPA-H funded performers, including small businesses, which help accelerate the commercialization of products. Small Business Award Opportunities Our Small Business Program uses innovative funding mechanisms, featuring a streamlined application and review process compared to traditional pathways.
Funding is available through Small Business Innovation Research (SBIR) awards and Small Business Technology Transfer (STTR) awards. Awards are generally issued in the form of contracts of up to $600K for Phase 1 and $3. 5M for Phase 2 awards and depend on meeting ambitious milestones, consistent with ARPA-H's model .
ARPA-H invites interested parties to review the solicitation, which is posted and maintained on SAM.
gov. Proposals that address one or more of the following topics are currently being considered: Topic 1: Development of an annual test to inform women about their future fertility Topic 2: Versatile Bioadhesives Topic 3: Universal Platform for Living Adaptive Toxin-removal (UNI-PLAT) Topic 4: Breaking Ground: The First Curative, Durable, Non-Surgical Therapy for Endometriosis Topic 5: ARPA-H Lineage Topic Topic 6: Rapid Comprehensive Diagnostic Test for Multi-System Autoimmune Disease Topic 7: Virtual Human Brain for the Development of Neurosurgical Robotics Solution Summary Due: July 10, 2026 (11:59AM ET) Applicants who are successful in the Solution Summary phase will be encouraged to pitch.
Technical Oral Presentation (Pitch), Cost Proposal, and Task Description Document Due: Anticipated September 9, 2026 (11:59AM ET) Reminder : Dates are estimates and subject to change. Please reference the solicitation for the most up-to-date information and proposal instructions. Review Solicitation Details To be eligible for SBIR or STTR awards, proposers must: Be a small business with no more than 500 employees.
Have majority ownership by U.S. Citizens or another U.S. based small business. Perform all work in the U.S. The Primary Investigator (PI) must be >50% employed by the small business. For Phase I, >66% of the work must be performed by the small business.
For Phase II, >50% of the work must be performed by the small business. The small business must have a Research Institution (RI) partner. The Primary Investigator (PI) must be >50% employed by the small business or RI.
For Phase I and Phase II, >40% of the work must be performed by the small business and >30% of the work must be performed by the RI. Frequently Asked Questions Review responses to common questions about this funding opportunity asked by others in the proposer community. You can also ask a question.
Review FAQs and Ask A Question This was an optional event for the proposer community to learn more about this opportunity, ask questions, and make connections. This event is not intended for patients, patient advocates, the media, or general interest audiences. View the Proposers' Day recording.
View the Proposers' Day slides. To report fraud, visit the NIH SEED page .
According to the current listing, eligibility includes: Small businesses with no more than 500 employees; majority ownership by U.S. Citizens or U.S.-based small businesses; all work performed in the U.S. Confirm the full requirements in the official notice before applying.
The current listing shows up to $600K for Phase 1; up to $3.5M for Phase 2. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs are due September 11, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs is funded by Advanced Research Projects Agency for Health (ARPA-H). Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program
Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) is sponsored by National Science Foundation (NSF) & National Institutes of Health (NIH). This interagency program supports high-risk, high-reward advances in AI and data science for biomedical and public health research. Projects must cross disciplinary boundaries.
Innovation Grant is a grant from the Delta Dental of Arizona Foundation that funds nonprofit organizations pursuing unique, high-impact projects that improve health and wellness in Arizona communities. This two-year award supports original initiatives with measurable real-world impact, including programs serving underserved and uninsured populations through oral health education, disease prevention, and nutritional access. Projects must demonstrate the potential to make a meaningful difference in the community and stand apart from conventional approaches. Eligible applicants are Arizona-based nonprofit organizations. Awards total $100,000 per recipient over two years. The 2026 application cycle closed October 16, 2025, with recipients notified in late 2025 and funding made available shortly after.
ARPA-H's 2026 SBIR/STTR BAA opens seven transformative health topics with $600K Phase I and $3.5M Phase II contracts — non-dilutive, milestone-driven money. The July 10 Solution Summary gate decides who ever gets to pitch. Here's how the ARPA-H model differs from NIH and how small health-tech firms actually get through the funnel.
Read articleARPA-H's FY2026 SBIR/STTR solicitation closes its Solution Summary stage July 10, with seven named topics spanning women's health, autoimmune diagnostics, toxin removal, and neurosurgical robotics. Awards run up to $600K for Phase I and $3.5M for Phase II — but they are contracts, not grants, and the four-to-six-page summary is the gate that filters out most applicants. Here is how ARPA-H's model actually works and how to win the first stage.
Read articleARPA-H's FY2026 SBIR/STTR solicitation opens with a Solution Summary due July 10, 2026, then a Technical Oral Presentation by September 9 for those invited. Awards run up to $600K (Phase I) and $3.5M (Phase II), with Direct-to-Phase-II and Fast Track options across seven health topic areas. Here is how the two-step, pitch-driven process differs from NIH SBIR — and how to win the first gate.
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