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Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs is sponsored by Various Federal Agencies (e.g., NIH). Congressionally mandated programs to ensure small businesses are included in federal spending on innovation and research. These grants are primarily for for-profit small businesses to develop innovative projects, often with an emphasis on commercialization.
For example, NIH offers STTR grants to develop serious STEM games with a focus on biology that addresses health and medicine questions.
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Or search similar grants →According to the current listing, eligibility includes: U.S.-based small businesses with fewer than 500 employees. Specific eligibility may vary by agency and solicitation. Confirm the full requirements in the official notice before applying.
The current listing shows varies by agency and phase (e.g., Phase 1 can be around $100,000). Verify award ceilings, matching requirements, and allowable costs in the official notice.
Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs is funded by Various Federal Agencies (e.g., NIH). Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
Past winners and funding trends for this program
OMB's proposed rewrite of 2 CFR Part 200 would bar political appointees from deferring to peer reviewers and require senior-appointee sign-off on every discretionary grant. NIH new awards are already down about 34% in 2026. Here is what the merit-review changes actually say, how 'Gold Standard Science' becomes a scoring lever, why R1 universities are being written out of some solicitations, and what principal investigators and research offices should do before October 1.
Read articleNIH's June 1 omnibus reset added Direct-to-Phase II to the STTR program for the first time. The change compresses university spinouts' funding timeline from three years to fifteen months, but the 30% research-institution subaward, feasibility-evidence rules, and IP licensing mechanics are not yet sorted at most universities.
Read articleNIH committed $402 million across 601 multiyear-funded grants in the first eight months of FY 2026 — more than four times the pace of two years ago. The mechanism front-loads obligations into a single fiscal year, leaving less budget for new project starts and squeezing FY 2026 success rates. What researchers and institutions should be doing now.
Read article