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Small Business Innovation Research (SBIR) Grants (R43 and R44) is sponsored by National Institute on Aging (NIA), National Institutes of Health (NIH). This program supports research and development of aging- and health-focused products and services by small business concerns that may ultimately lead to commercialization.
This includes innovative tools, technologies, and interventions to prevent, diagnose, treat, monitor, or slow progression of AD/ADRD, cognitive decline, age-related sleep disorders, and delirium.
Also includes technologies and interventions that promote healthy aging, support aging in place of choice, improve care delivery, or reduce caregiving burden, such as assistive devices, robotics, sensors, digital health products, and technologies to enhance care.
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Or search similar grants →According to the current listing, eligibility includes: Small businesses (SBCs) where the principal investigator (PI) has primary employment (greater than 50%) with the SBC at the time of the award and during the conduct of the project. Must be located and operating in the United States and have no more than 500 employees. Confirm the full requirements in the official notice before applying.
The current listing shows up to $500,000 for Phase I; up to $2.5 million for Phase II (non-AD/ADRD related); up to $700,000 for Phase I and $3 Million for Phase II (AD/ADRD related). Verify award ceilings, matching requirements, and allowable costs in the official notice.
The published deadline was September 5, 2026, which has passed. Check the official notice for any future application windows before investing time in a proposal.
Small Business Innovation Research (SBIR) Grants (R43 and R44) is funded by National Institute on Aging (NIA), National Institutes of Health (NIH). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program
NIA Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs is sponsored by National Institute on Aging (NIA), National Institutes of Health (NIH). The NIA SBIR/STTR programs support small businesses in developing technologies for aging-related health issues, including AI-driven drug discovery tools and assistive technologies for older adults aging in place. These programs aim to help small businesses develop effective treatments and interventions for healthy aging.
Small Business Technology Transfer (STTR) Program is sponsored by National Institute on Aging (NIA), National Institutes of Health (NIH). The NIA STTR program encourages small businesses to collaborate formally with research institutions to develop and commercialize innovative treatments or technologies to help people enjoy healthier lives as they age, including solutions for Alzheimer's disease and related dementias. This program supports feasibility studies to later stage research and development (R&D) needed to develop a commercial product.
The Small Business Innovation Research (SBIR) Program for CHIPS for America – CHIPS Metrology seeks applications from eligible applicants to explore the technical merit or feasibility of an innovative idea or technology with the aim of developing a viable product or service that will be introduced to the commercial microelectronics marketplace. This NOFO contains multiple topics on research projects for critically needed measurement services, tools, and instrumentation; innovative manufacturing metrologies; novel assurance and provenance technologies and advanced metrology research and development (R&D) testbeds to help secure U.S. leadership in the global semiconductor industry. Funding Opportunity Number: 2024-SBIR-CHIPS-01. Assistance Listing: 11.042,11.620. Funding Instrument: CA. Category: ST.
JobsOhio Small Business Grant is sponsored by JobsOhio. This grant offers financial support for real estate investments, equipment, and more for eligible projects and businesses. While broad in scope, if the autonomous scientific instrumentation or miniaturized microscope sensor payload directly leads to job creation or significant fixed-asset investment in Ohio, it could be relevant.
NOT-OD-26-098 consolidates NIH career development awards into four parent NOFOs (KR1, KC1, KS1, KT1), eliminates the Data Management and Sharing Plan for K applications, and stops supporting K awards that let the awardee lead their own clinical trial. The RFI closes September 30, 2026; the new structure hits due dates on or after October 12, 2027.
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