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Small Business Innovation Research (SBIR) Phase IIB Bridge Awards is sponsored by National Heart, Lung, and Blood Institute. Small Business Innovation Research (SBIR) Phase IIB Bridge Awards from the National Heart, Lung, and Blood Institute (NHLBI) fund later-stage research and development for small businesses with promising technologies requiring eventual Federal regulatory approval.
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Opportunity Listing - NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional) NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional) Agency: National Institutes of Health Assistance Listings: 93.
233 -- National Center on Sleep Disorders Research 93. 839 -- Blood Diseases and Resources Research 93. 840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders 93.
838 -- Lung Diseases Research 93. 837 -- Cardiovascular Diseases Research Last Updated: May 13, 2026 View version history on Grants. gov The Small Business Innovation Research (SBIR) Program is an important funding mechanism that the National Institutes of Health (NIH) uses to develop innovative solutions that address public health challenges.
A major objective of the SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of biomedical products is often impeded by a significant funding gap between the end of the SBIR Phase II award and the commercialization stage.
This Notice of Funding Opportunity (NOFO) invites SBIR grant applications from SBCs to support later-stage research and development (referred to as Phase IIB) for promising projects that were previously funded by SBIR or STTR Phase II awards and will require eventual Federal regulatory approval/clearance.
The goal of this NOFO and the resulting Phase IIB awards is to assist applicants in pursuing the milestone(s) necessary to advance a product to regulatory approval and commercialization by promoting partnerships between SBIR Phase II awardees and third-party investors and/or strategic partners. Projects proposed under this NOFO MUST be relevant to the NHLBI mission (see B. Scientific/Technical Scope).
This NOFO is specifically intended to benefit clinical practice by accelerating the commercialization of novel products that require ultimate approval/clearance by a Federal regulatory agency.
This NOFO will give competitive preference and funding priority to applications deemed likely to result in a clinically-relevant commercial product as indicated by the applicants ability to secure independent third-party investor funds that equal or exceed the requested NHLBI funds (total costs). Other Eligible Applicants include the following:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed. Grantor contact information See Section VII.
Agency Contacts within the full opportunity announcement for all other inquires. File name Description Last updated RFA-HL-26-014-Full-Announcement. html RFA-HL-26-014 Full Announcement Text Nov 19, 2024 08:10 PM UTC Link to additional information https://grants.
nih. gov/grants/guide/rfa-files/RFA-HL-26-014. html Archived: November 18, 2025 Funding opportunity number : Cost sharing or matching requirement : Funding instrument type : Opportunity Category Explanation : Category of Funding Activity : Your account requires additional identity verification.
According to the current listing, eligibility includes: Small businesses. Confirm the full requirements in the official notice before applying.
The current listing shows $1,500,000. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Small Business Innovation Research (SBIR) Phase IIB Bridge Awards is funded by National Heart, Lung, and Blood Institute. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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