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Find similar grantsThe NSF SBIR program supports U. S. -based startups and small businesses developing high-risk, high-impact technologies with strong commercial potential, including AI applications in healthcare and drug discovery.
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Or search similar grants →According to the current listing, eligibility includes: U. S. -based small businesses (fewer than 500 employees) with at least 50% equity owned by U. S. citizens or permanent residents. Confirm the full requirements in the official notice before applying.
The current listing shows up to $305,000 for Phase I; Up to $1,250,000 for Phase II. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Small Business Innovation Research (SBIR) Program is funded by National Science Foundation (NSF) Small Business Innovation Research (SBIR) Program. Verify program details on the funder's official page before applying.
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Digital Health (DH) - NSF SBIR is sponsored by National Science Foundation (NSF) Small Business Innovation Research (SBIR) Program. This opportunity supports entrepreneurs and startups in developing innovative digital health technologies to improve physical or mental wellbeing, enable independence, and enhance healthcare delivery. It includes assistive, enabling, and rehabilitative technologies.
Instrumentation and Hardware Systems (IH) Topic is sponsored by National Science Foundation (NSF) Small Business Innovation Research (SBIR) Program. This topic addresses the research and development of new and improved instrumentation and related systems for a wide variety of commercial and industrial applications. Proposals may deal with new instruments for use in scientific, industrial, engineering, or manufacturing environments, among others. Systems and tools designed for detection, manipulation, characterization, measurement, processing, control, or monitoring will be considered.
The Small Business Innovation and Economic Security Act of 2026 saved the programs after a six-month lapse, but it also added $30M strategic-breakthrough awards, per-company proposal caps, and mandatory national-security screening. Here is what changed across all eleven SBIR agencies — and what it means for your next proposal.
Read articleS.3971 reauthorizes SBIR/STTR through 2031 with strategic breakthrough funding, security screening, and proposal caps. What changed and how to compete.
Read articleThe SBIR/STTR reauthorization through 2031 introduces Strategic Breakthrough Awards up to $30M, proposal caps, and enhanced security vetting. What small businesses need to know now.
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