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Small Business Technology Transfer Grant Parent STTR [R41/R42] Clinical Trial Optional is sponsored by National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), and Food and Drug Administration (FDA). This program expands funding opportunities for small businesses in the federal innovation research and development arena.
It requires a formal collaboration between a small business and a non-profit U.S. research institution for cooperative R&D. The goal is to stimulate technological innovation and increase commercialization of R&D.
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Opportunity Listing - PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) Agency: National Institutes of Health Assistance Listings: 93. 867 -- Vision Research 93.
879 -- Medical Library Assistance 93. 838 -- Lung Diseases Research 93. 394 -- Cancer Detection and Diagnosis Research 93.
233 -- National Center on Sleep Disorders Research 93. 837 -- Cardiovascular Diseases Research 93. 213 -- Research and Training in Complementary and Integrative Health 93.
393 -- Cancer Cause and Prevention Research 93. 307 -- Minority Health and Health Disparities Research 93. 840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders 93.
839 -- Blood Diseases and Resources Research 93. 286 -- Discovery and Applied Research for Technological Innovations to Improve Human Health 93. 113 -- Environmental Health 93.
361 -- Nursing Research 93. 273 -- Alcohol Research Programs 93. 395 -- Cancer Treatment Research 93.
865 -- Child Health and Human Development Extramural Research 93. 172 -- Human Genome Research 93. 173 -- Research Related to Deafness and Communication Disorders 93.
242 -- Mental Health Research Grants Last Updated: May 13, 2026 View version history on Grants. gov This Notice of Funding Opportunity Announcement (NOFO), issued by the National Institutes of Health (NIH) invites eligible United States small businesses to submit Small Business Technology Transfer (STTR) grant applications.
United States small businesses that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH awarding components identified in this NOFO are encouraged to submit STTR grant applications in response to identified topics (see SBIR/STTR Program Descriptions and Research Topics for NIH, CDC, and FDA).
This Parent Funding Opportunity Announcement requires that at least 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. Other Eligible Applicants include the following:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed. Grantor contact information See Section VII.
Agency Contacts within the full opportunity announcement for all other inquires. File name Description Last updated PA-24-248-Full-Announcement. html PA-24-248 Full Announcement Text Link to additional information https://grants.
nih. gov/grants/guide/pa-files/PA-24-248. html Archived: October 5, 2025 Funding opportunity number : Cost sharing or matching requirement : Funding instrument type : Opportunity Category Explanation : Category of Funding Activity : Income security and social services Your account requires additional identity verification.
According to the current listing, eligibility includes: For-profit small businesses that are majority American-owned and have fewer than 500 employees, in formal collaboration with a U.S. research institution. Confirm the full requirements in the official notice before applying.
Applications for Small Business Technology Transfer Grant Parent STTR [R41/R42] Clinical Trial Optional are due September 5, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Small Business Technology Transfer Grant Parent STTR [R41/R42] Clinical Trial Optional is funded by National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), and Food and Drug Administration (FDA). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) (PA-27-100) is sponsored by National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), and Food and Drug Administration (FDA). This funding opportunity supports U.S. small business concerns (SBCs) in conducting research and development (R&D) to bring scientific innovations to the marketplace. It encompasses Phase I, Phase II, Direct to Phase II, and Fast-Track applications and is the parent funding opportunity for most biotech, diagnostic, digital-health, and medical-device small businesses. The NOFO is 'Clinical Trial Optional', allowing applicants to propose or not propose clinical trials depending on individual Institute/Center rules. The small business should perform the majority of the research, and the Program Director/Principal Investigator should be primarily employed by the small business.
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional) is sponsored by National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), and Food and Drug Administration (FDA). This program expands funding opportunities in the federal innovation research and development arena by fostering partnerships between small businesses and non-profit research institutions. It provides non-dilutive funding for early-stage research and development with a strong emphasis on commercialization.
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Not Allowed) is sponsored by National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), and Food and Drug Administration (FDA). This funding opportunity invites eligible United States small businesses to submit Small Business Innovation Research (SBIR) grant applications.
NCI Continuing Umbrella of Research Experiences (CURE) Academic Career Excellence (ACE) Award (K32) is a grant from the National Cancer Institute (NCI) that funds early postdoctoral fellows from diverse backgrounds, including underrepresented groups, to pursue research training in cancer-related fields. The K32 award supports fellows within 12 months prior to transitioning into, or within the first two years of, a postdoctoral position. The program, operated through NCI's Center to Reduce Cancer Health Disparities (CRCHD), aims to enhance the pool of qualified diverse cancer researchers. Beginning with the June 12, 2025 due date, the CURE ACE Award is available in both Independent Clinical Trial Required and Independent Clinical Trial Not Allowed versions. Eligible applicants must be U.S. citizens or permanent residents at time of award.
Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) is sponsored by National Science Foundation (NSF) & National Institutes of Health (NIH). This interagency program supports high-risk, high-reward interdisciplinary projects that leverage AI, machine learning, and advanced data science to address pressing questions in biomedical and public health research. It seeks to advance fundamental scientific and engineering contributions across disciplines to solve key health problems.
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