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Small Business Technology Transfer (STTR) Program (Omnibus/Parent Grant Solicitation) is sponsored by National Institutes of Health (NIH) / Department of Health and Human Services (HHS). Similar to the SBIR program, the STTR program funds small businesses for research and development with commercial potential, with a key difference being the requirement for a formal collaboration with a non-profit research institution.
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Opportunity Listing - PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) Agency: National Institutes of Health Assistance Listings: 93. 867 -- Vision Research 93.
879 -- Medical Library Assistance 93. 838 -- Lung Diseases Research 93. 394 -- Cancer Detection and Diagnosis Research 93.
233 -- National Center on Sleep Disorders Research 93. 837 -- Cardiovascular Diseases Research 93. 213 -- Research and Training in Complementary and Integrative Health 93.
393 -- Cancer Cause and Prevention Research 93. 307 -- Minority Health and Health Disparities Research 93. 840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders 93.
839 -- Blood Diseases and Resources Research 93. 286 -- Discovery and Applied Research for Technological Innovations to Improve Human Health 93. 113 -- Environmental Health 93.
361 -- Nursing Research 93. 273 -- Alcohol Research Programs 93. 395 -- Cancer Treatment Research 93.
865 -- Child Health and Human Development Extramural Research 93. 172 -- Human Genome Research 93. 173 -- Research Related to Deafness and Communication Disorders 93.
242 -- Mental Health Research Grants Last Updated: May 13, 2026 View version history on Grants. gov This Notice of Funding Opportunity Announcement (NOFO), issued by the National Institutes of Health (NIH) invites eligible United States small businesses to submit Small Business Technology Transfer (STTR) grant applications.
United States small businesses that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH awarding components identified in this NOFO are encouraged to submit STTR grant applications in response to identified topics (see SBIR/STTR Program Descriptions and Research Topics for NIH, CDC, and FDA).
This Parent Funding Opportunity Announcement requires that at least 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. Other Eligible Applicants include the following:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed. Grantor contact information See Section VII.
Agency Contacts within the full opportunity announcement for all other inquires. File name Description Last updated PA-24-248-Full-Announcement. html PA-24-248 Full Announcement Text Link to additional information https://grants.
nih. gov/grants/guide/pa-files/PA-24-248. html Archived: October 5, 2025 Funding opportunity number : Cost sharing or matching requirement : Funding instrument type : Opportunity Category Explanation : Category of Funding Activity : Income security and social services Your account requires additional identity verification.
According to the current listing, eligibility includes: For-profit small businesses (500 or fewer employees) primarily based in the U. S. , with at least 50% equity owned by U. S. Confirm the full requirements in the official notice before applying.
The current listing shows varies (Phase I typically up to $275,000, Phase II higher). Verify award ceilings, matching requirements, and allowable costs in the official notice.
Small Business Technology Transfer (STTR) Program (Omnibus/Parent Grant Solicitation) is funded by National Institutes of Health (NIH) / Department of Health and Human Services (HHS). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional) is sponsored by National Institutes of Health (NIH) / Department of Health and Human Services (HHS). This program, part of the larger SBIR/STTR initiative, is focused on advancing the commercialization of technologies developed through prior SBIR/STTR awards. It provides funding for later-stage development to help bring innovations to market.
SBIR/STTR Omnibus Solicitation (Parent Announcements) is sponsored by National Institutes of Health (NIH) / Department of Health and Human Services (HHS). These broad funding opportunities allow small businesses to submit investigator-initiated applications for research and development that aligns with the missions of the participating NIH Institutes and Centers. The program aims to stimulate technological innovation and increase private-sector commercialization of federally funded R&D.
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