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Special Projects of National Significance is sponsored by Department of Health And Human Services. The purpose of the Ryan White HIV/AIDS Program (RWHAP) Part F Special Projects of National Significance (SPNS) Program is to support the development of innovative models of HIV care and treatment to quickly respond to emerging needs of RWHAP clients.
Through its demonstration, implementation, and health information technology projects, SPNS uses implementation science to evaluate the design, implementation, use, cost, and health-related outcomes of treatment strategies while promoting the dissemination and replication of successful interventions in the RWHAP.
This unique program advances knowledge and skills in the delivery of health care, support services, and data integration to serve RWHAP priority populations. Through these special projects, RWHAP SPNS recipients implement a variety of interventions that advance public health knowledge and help to achieve the goal of ending the HIV epidemic in the United States. This listing is currently active.
Program number: 93. 928. Last updated on 2026-01-12.
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Search similar grants →According to the current listing, eligibility includes: Academic institutions, non-profit organizations including faith-based organizations, and those eligible for funding under Parts A-D authorized by Title XXVI of the Public Health Service (PHS) Act. Additionally, federally recognized Indian Tribal Governments and tribal organizations are also eligible to apply for these funds. Eligible applicant types include: U.S. Territory (or Possession) Government (including freely-associated states), U.S. State Government (including the District of Columbia), Local, Federally Recognized Indian/Native American/Alaska Native Tribal Government, Indian/Native American/Alaska Native Tribal Government (Other than Federally Recognized), Other. Confirm the full requirements in the official notice before applying.
Yes — Special Projects of National Significance is offered by Department of Health And Human Services and this listing comes from SAM.gov, an official U.S. federal source. Federal applications generally require registrations (for example SAM.gov or an agency submission portal), so allow extra lead time.
This opportunity targets applicants in Alaska and District of Columbia. Check the official notice for exact location requirements.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program
Utah Primary Care Grant Program is a grant from the Utah Department of Health and Human Services – Office of Primary Care and Rural Health that funds organizations providing primary healthcare to medically underserved and low-income populations across Utah. The program increases access to ambulatory primary care services for low-wage workers, children, the elderly, migrant farmworkers, and the uninsured or underinsured. Eligible applicants include private non-profit and public organizations delivering primary healthcare in Utah. The 2026 application cycle opened March 9 and closed March 31, 2026, with an application orientation held on March 17.
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