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Synthesis and Biological Activity Assessment of Different Diastereomers in siRNA Drug LEQVIO (Inclisiran) (U01) Clinical Trial Not Allowed is sponsored by Food and Drug Administration. Synthesis and Biological Activity Assessment of Different Diastereomers in siRNA Drug LEQVIO (Inclisiran) (U01) Clinical Trial Not Allowed is a forecasted funding opportunity on Grants. gov from Food and Drug Administration.
Fiscal Year: 2024. Assistance Listing Number(s): 93. 103.
<p><span style="color: black;">The purpose of this research is to systematically evaluate the diastereomeric composition of LEQVIO (Inclisiran), an FDA-approved, N-acetyl galactosamine (GalNAc)-conjugated siRNA drug, and to understand the biological/pharmacological activity of each diastereomer in LEQVIO through stereo chemically controlled synthesis and biological activity assessment using in vitro and animal models.
The proposed studies will focus on 1) synthesis of each diastereomer of LEQVIO...
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Or search similar grants →According to the current listing, eligibility includes: Eligible applicant types: Independent school districts, Native American tribal organizations (other than Federally recognized tribal governments), Native American tribal governments (Federally recognized), Others (see text field entitled "Additional Information on Eligibility" for clarification), City or township governments, For profit organizations other than small businesses, State governments, Public housing authorities/Indian housing authorities, County governments, Special district governments, Private institutions of higher education, Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility", Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Small businesses, Public and State controlled institutions of higher education. Confirm the full requirements in the official notice before applying.
Yes — Synthesis and Biological Activity Assessment of Different Diastereomers in siRNA Drug LEQVIO (Inclisiran) (U01) Clinical Trial Not Allowed is offered by Food and Drug Administration and this listing comes from Grants.gov, an official U.S. federal source. Federal applications generally require registrations (for example SAM.gov or an agency submission portal), so allow extra lead time.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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