Systemic Autoimmune Disease Biology Program

Systemic Autoimmune Disease Biology Program is sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). This program supports basic, translational, and clinical studies on systemic autoimmune diseases, including lupus and autoimmune myositis. NIAMS supports research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases.

Grants & Funding: NIAMS Extramural Program | NIAMS NIH Websites Are Changing Grants & Funding: NIAMS Extramural Program Planning, developing, awarding, and managing basic, translational, and clinical scientific research studies and training Upcoming Receipt Date for Ancillary Studies to Ongoing Clinical Projects Read the Agenda for the Upcoming April 21, 2025 NIAMS Advisory Council Meeting Notice of Special Interest (NOSI): Supporting Research Using the Resources from the Osteoarthritis Initiative (OAI) The NIAMS Extramural Program (EP) plans, develops, awards, and manages basic, translational, and clinical scientific research studies and training throughout the United States and abroad within the scientific mission of NIAMS through a wide array of grants, contracts, and cooperative agreements to universities, hospitals, medical schools, small businesses and other organizations.

The goal is to facilitate the most promising discoveries and emerging technologies for rapid translation to clinical applications for improving public health. In the current fiscal year we expended about 85% of our budget on extramural research, by providing over $500 million in funding for 1,500 extramural grants and cooperative agreements. Gayle Lester, Ph.

D. , Director, Division of Extramural Research Darren Sledjeski, Ph. D.

, Director, Division of Extramural Activities Supported Scientific Programs Arthritis Biology Program Basic, translational, and clinical research on a number of arthritic diseases, including rheumatoid arthritis, juvenile arthritis, Lyme arthritis, and more.

Bone Biology, Metabolic Bone Disorders, and Osteoporosis Program This program supports research on bone biology, clinical research on osteoporosis, metabolic bone disorders and bone quality. Cartilage and Connective Tissue Program Research on cartilage and connective tissue, and the conditions that affect them.

Clinical Osteoarthritis and Diagnostic Imaging Program Research on clinical osteoarthritis; bone quality and skeletal imaging; and human genetics of bone and cartilage. Clinical, Integrative Physiology, and Rare Diseases of Bone Program Research to study the mechanisms, pathogenesis, and pathophysiology of bone diseases and their interaction with tissues and organs.

Epidermis, Dermis and Skin Senses Program Research basic, translational, and clinical studies of extracellular matrix (ECM) biology and diseases. Muscle Development and Physiology Program Research to understand the development, growth, and maintenance of muscle tissue, including muscle regeneration and the biology of stem cells.

Muscle Disorders and Therapies Program Research on acquired and inherited diseases of the skeletal muscle, and muscle atrophy and injury. Musculoskeletal Tissue Engineering and Regenerative Medicine Program Research on tissue engineering and repair of musculoskeletal tissues that explores new approaches to tissue regeneration.

Orthopaedic Implant Science Program The Orthopaedic Implant Science Program supports preclinical testing and development of orthopaedic implants and preclinical studies on implant wear and osteolysis. Orthopaedic Research Program Research on orthopedics and musculoskeletal rehabilitation, including studies of orthopedic devices and joint replacement.

Rheumatic Diseases Integrative Biology Research Program This program supports human genetic and genomic, biopsychosocial and behavioral, and pain related research in rheumatic diseases, with a goal to understand how a person’s genetics, environmental, behavioral and lifestyle factors influence health and to understand the best approach to prevent and treat diseases, ultimately bringing precision medicine to patients.

Scleroderma, Fibrosis, and Autoinflammatory Disease Program The Scleroderma, Fibrosis and Autoinflammatory Disease Program supports studies of basic, translational, and pre-clinical studies on scleroderma, fibrosis, and autoinflammatory diseases. Skin Immunology and Diseases, Skin Microbiome Program Research on the immunobiology of the skin, including the regulation of skin immune responses and immune system cellular components.

Skin Repair, Pigmentation and Appendages, Vasculature/Lymphatic Systems Program Research on epidermal repair and regeneration and melanocyte biology, including the wound healing process and skin cell development. Systemic Autoimmune Disease Biology Program Basic, translational, and clinical research on systemic autoimmune diseases, including lupus and autoimmune myositis. The NIAMS FY2025 funding plan for research and training grants.

Conducting Clinical Trials The clinical trials program is designed to support studies with different levels of complexity and risk. NIAMS Grants Administration Resources Policies and procedures for administering an NIH grant. NIAMS-Supported Research Programs Learn more about NIAMS funded research programs currently underway.

Research Training and Career Development Programs Learn about the training programs NIAMS offers, for trainees and researchers throughout career pathways. NIH Policies and Guidance NIAMS and NIH requirements for all grant awardees. NIH Loan Repayment Program (LRP) Learn about the NIH LRP, a resource designed to recruit and retain highly qualified health professionals into biomedical or biobehavioral research careers.

View all scientific programs View all scientific programs Clear Plastic Aligners Give Patients with Brittle Teeth New Smiles NIAMS-Related Article | September 10, 2024 Array of Patient Recruitment Efforts Boost Back Pain Study Participation Spotlight on Research | September 10, 2024 Researchers Identify a Disease-Causing Immune Cell Imbalance in Lupus Spotlight on Research | September 4, 2024 Connective Tissue Disorders NIAMS-Related Article | September 4, 2024 A Nanomaterial One-Two Punch Quickly Heals Wounds in Diabetic Animal Model NIAMS-Related Article | June 4, 2024 New Awardees Aim to Develop National Research Network That Will Explore the Role of the Exposome in Autoimmune Diseases Announcement | March 5, 2024 View All Research Highlights NIH, NIAMS, Extramural Program Grant Application Resources How Grant Funding Decisions are Made See if NIAMS is the best place for your research by using Matchmaker .

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