Technology Development Seed Grants

Technology Development Seed Grants is sponsored by Beckman Center at Stanford Medicine. Supports innovative projects focusing on the development of new instruments, devices, or methodologies in biomedical research.

Technology Development Seed Grants | Beckman Center | Stanford Medicine Technology Development Seed Grants The seed grant program stimulates collaborations across disciplines so research discoveries can be translated into therapeutic applications.

Seed Grants to Foster Innovation More than 20 years ago, the Beckman Center launched the Technology Development Seed Grant program to foster the development and dissemination of new research technologies. The program funds proposals that support innovative applications for 1) the development of new and improved instruments or devices, or 2) the development of new methodologies to be used in biomedical research.

Projects selected for funding feature novel ideas and represent high-risk, high-reward research that could potentially attract larger federal grant awards. Preference is given to research that is collaborative and multidisciplinary, and that forges interfaces between the basic and clinical sciences, so that laboratory research and discovery can be “translated” into new diagnostic and therapeutic applications.

Teams are composed of two or more researchers, including combinations of physician investigators, basic scientists, applied scientists, and others. Since its inception, more than 60 grant awards have been made to faculty researchers across campus, drawn from the schools of Medicine, Engineering, and Humanities and Sciences.

The Technology Development Seed Grant projects have resulted in promising outcomes that include significant research data, published papers, grant and patent applications, and media coverage. Grant Eligibility and Funding Applicants for Technology Development Seed Grant awards should be Stanford University faculty members holding university, research, or medical center line positions (UTL, MCL, or NTLR faculty appointments).

PMGM advisory committee members evaluate the proposals and the center provides $100,000 per year, for a two-year period, to the best proposals.

Get information on eligibility, submission deadlines, and the selection process Discover the Technology Development Seed Grant Awards Current Technology Development Seed Grant Awards A New Tool for High-Density Thalamic Neural Signal Recording and Modulation for Neurological and Neuropsychiatric Disease Diagnosis and Treatment. Zhenan Bao, Department of Chemical Engineering; Vivek P.

Buch, Department of Neurosurgery A Proteomic Biosensor Platform for Multiplexed Readout of Endogenous Kinase Activity with Subcellular Resolution. Ruth Huttenhain, Department of Molecular and Cellular Physiology; Alice Y. Ting, Departments of Genetics and Biology All-Optical Platform for Probing Single-Cell Neuropeptidergic Connectivity in the Central Nervous System.

Rongxin Fang, Department of Neurosurgery; Kang Shen, Department of Biology Enabling Cryo-ET of Tissue-Derived Specimens via Custom Grids and Needle Biopsies. Daniel Bernstein, Department of Pediatrics - Cardiology; Peter Dahlberg, Departments of Structural Biology and SLAC National Accelerator Laboratory; Alexander Dunn, Department of Chemical Engineering Innovating Far-UVC Led Technologies for Scalable Pandemic Prevention.

Jason Andrews, Department of Medicine - Med/Infectious Diseases; Srabanti Chowdhury, Department of Electrical Engineering; Daniel Congreve, Department of Electrical Engineering; Stephen P. Luby, Department of Medicine – Med/Infectious Diseases Previous Technology Development Seed Grant Awards A Systemic Light Source for Optogenetic Screening of Enteric Nervous System Functions.

Guosong Hong, Department of Materials Science and Engineering; Julia Kaltschmidt, Department of Neurosurgery An Integrated Milli-Fluidic System for Automated Tissue Dissociation into Single Cells. James D. Brooks, Department of Urology - Divisions; Sindy Kam-Yan Tang, Department of Mechanical Engineering Breaking the Barriers to Discovering Biologics Against Membrane Proteins .

Le Cong, Departments of Pathology and Genetics; Liang Feng, Department of Molecular and Cellular Physiology Development of a Photo-Enzymatic 3D Bioprinter for Pediatric Tissue Engineered Vascular Grafts . Steven G. Boxer, Department of Chemistry; Michael Ma, Department of Cardiothoracic Surgery; Mark A.

Skylar-Scott, Department of Bioengineering Fluorescent Lifetime Imaging Microscopy of Mitochondria-Rich Extracellular Vesicles for Direct Augmentation of Myocardial Bioenergetics . Mark A. Kasevich, Departments of Physics and Applied Physics; Soichi Wakatsuki, Departments of SLAC National Accelerator Laboratory, Structural Biology, and Energy Sciences; Phillip C.

Yang, Department of Medicine - Med/Cardiovascular Medicine A Next-Generation Imaging Technology for Human Tissue Atlases. Tushar Desai, Department of Medicine (Pulmonary and Critical Care); Pehr A. B.

Harbury, Department of Biochemistry Developing FFPE-Optimized CODEX to Reveal the Cutaneous T Cell Lymphoma Tumor Microenvironment in Response to Immunotherapy. Youn H. Kim, Department of Dermatology; Garry Nolan, Department of Pathology Optical Tools to Assess Neuronal Function in Human Stem Cell-Based Disease Models .

Alice Ting, Departments of Genetics and Biology; Marius Wernig, Department of Pathology Scalable Long-Term DNA Storage with Error Correction and Random-Access Retrieval . Hanlee P. Ji, Department of Medicine (Oncology); Tsachy Weissman, Department of Electrical Engineering Targeting the Influenza Matrix Layer Through Hyper-Stabilization .

Wah Chiu, Departments of Photon Science, Bioengineering, and Microbiology and Immunology; Karla Kirkegaard, Departments of Genetics, and Microbiology and Immunology Building a Complete Machine Learning Toolkit for Faster Autism Detection and Care at Home.

Carl Feinstein, Child Psychiatry; Dennis Wall, Pediatrics, Systems Medicine, Bioinformatics; Terry Winograd, Computer Science Mechanogenetics: Ultrasound-Triggered Cell-Type-Specific Brain Control.

Jin Hyung Lee, Neurology and Neurosurgery, Bioengineering; Jan Liphardt, Bioengineering SC TRAP-Seq: Leveraging Spectrally-Encoded Beads to Enable High-Throughput Single Cell Tandem RNA and Protein (SC-TRAP) Analysis in a Novel Assay as Applied to Glioblastoma. Polly Fordyce, Genetics, Bioengineering; Melanie Hayden Gephardt, Neurosurgery Massively Parallel Arrays for Immune Profiling. William Greenleaf, Genetics; Jörg J.

Goronzy, Medicine/Immunology and Rheumatology Novel Experimental Platform Utilizing Directed Evolution for Patient-Specific Determination of Antigen Recognition by Defined T Cell Clone. H. Everett Myer, Medicine/Blood and Marrow Transplantation; Michael Mindrinos, Biochemistry; Ronald Davis, Biochemistry Nanolaser and Nanoresonator Probes Inside Single Living Cells for Intracellular Optical Sensing and Control.

Jelena Vuckovic, Electrical Engineering; Sanjiv Gambhir, Radiology Single-Molecule Structure and Dynamics via Tracking Cross-Correlation Spectroscopy. Hideo Mabuchi, Applied Physics; Aaron Straight, Biochemistry Allogenic Graft-Versus-Lymphoma Effects in Cutaneous T Cell NHL .

Youn Kim, Dermatology; Richard Hope, Radiation Oncology; Christopher Contag, Pediatrics and Microbiology; Wen Kai Weng, Medicine/Bone and Marrow Transplantation Defining the Primary Immune Response to Epstein Barr Virus in Transplant Recipients .

William Berquist, Pediatrics; Carlos Esquivel, Surgery/Transplantation; Sheri Krams, Surgery/Program in Immunology; Olivia Martinez, Surgery/Program in Immunology; José Montoya, Medicine/Infectious Diseases Engineering and Development of Interleukin-2 Superkines with Improved Therapeutic Utility . C. Garrison Fathman, Medicine/Immunology and Rheumatology; K.

Christopher Garcia, Molecular and Cellular Physiology, Structural Biology; Robert S. Negrin, Medicine/Blood and Bone Marrow Transplantation; Lawrence Steinman, Neurology Identification of Host Factors that Contribute to Defective Inflammasome Activation in Monocytes from Patients with Systemic Juvenile Idiopathic Arthritis .

Elizabeth Mellins, Pediatrics; Denise Monack, Microbiology & Immunology Identifying Inflammatory Drivers of Chronic Fatigue via Daily Immune and Symptom Sampling . Rachel Manber, Psychiatry and Behavioral Sciences; Jared Younger, Anesthesia Immune System Dynamics in Early Cardiovascular Aging . Atul J.

Butte, Pediatrics/Systems Medicine; Francois Haddad, Medicine/Cardiology; Olivia Martinez, Surgery/Program in Immunology; José Montoya, Medicine/Infectious Diseases; Ingela Schnittger, Medicine/Cardiology; Joseph C. Wu, Medicine Single-Cell Analysis of Disease-Specific T Cells in Celiac Sprue .

Mark Davis, Microbiology & Immunology; Chaitan Khosla, Chemistry and Chemical Engineering Telomere Protection in Progenitor Cells and Lymphocytes During Aging and Autoimmune Disease . Gil Chu, Medicine/Biochemistry; Stephen Quake, Bioengineering and Applied Physics; Dolly B. Tyan, Pathology; Cornelia Weyand, Medicine/Rheumatology; Julie M.

Yabu, Medicine/Nephrology The Role of Astrocytes in Modulating Brain Immune Responses . John C. Boothroyd, Neurology and Neurological Sciences; Marion Buckwalter, Neurology and Neurological Sciences Transplantation Methods for Intestinal Stem Cells .

C. Andrew Bonham, Surgery; Sheri Krams, Surgery/Transplantation; Calvin Kuo, Medicine; Karl Sylvester, Surgery and Pediatrics Characterization of Innate Immune Pathways Leading to Inflammasome Activation . Petr Broz, Microbiology & Immunology Novel Mechanisms for HCV Induced Cellular Transformation .

Shirit Einav, Medicine Oral Bacteriophage Communities . David Pride, Medicine A Systems Biology Approach for Discovery of Biomarkers for Inflammatory Pain . Atul Butte, Pediatrics; Martin Angst, Anesthesiology; Brendan Carvalho, Anesthesiology; Eliza Chakravarty, Immunology and Rheumatology; David Clark, Anesthesiology; David Schneider, Microbiology & Immunology Comprehensive Immunophenotyping of Patients with Primary Immunodeficiency .

David Lewis, Pediatrics; Kari Nadeau, Pediatrics; P. J. Utz, Medicine/Immunology and Rheumatology Cryptic Translation of MHC I-Presented Peptides by Specialized Ribosomes .

Joseph Puglisi, Structural Biology; Peter Sarnow, Microbiology & Immunology Definition of the Ligand for CD83 and Its Signaling Pathway . C. Garrison, Medicine/Immunology and Rheumatology; Garry Nolan, Microbiology & Immunology Development of a Microbial Antigen Array for Multiplex, Longitudinal, Analysis of Exposure to Infections Agents .

David Miklos, Medicine/Blood and Bone Marrow Transplantation; Julie Parsonett, Medicine/Infectious Diseases Immunophenotyping of Subjects with Near-Fatal Food Allergy . Edgar Engleman, Pathology; Stephen Galli, Pathology, Microbiology & Immunology; Kari Nadeau, Pediatrics; Mindy Tsai, Pathology MiRNA Expression and Dysregulation in Autoimmunity .

Chan-Zhang Chen, Microbiology & Immunology; Mark Davis, Microbiology & Immunology; Mark Genovese, Medicine/Immunology and Rheumatology; David Hirschberg, HIMC; William Robinson, Medicine/Immunology and Rheumatology; P. J. Utz, Medicine/Immunology and Rheumatology Prediction and Mechanisms of Transplantation Tolerance .

Minnie Sarwal, Pediatrics; Samuel Strober, Medicine/Immunology and Rheumatology Combined Intratumoral Injection of Bone Marrow-Derived Dendritic Cells and Systemic Chemotherapy to Treat Established Experimental Malignant Glioma . Lawrence Recht, Neurology; Ronald Levy, Medicine/Oncology Dendritic Cell Function During Viral Infection .

Edgar Engleman, Pathology; Karla Kirkegaard, Microbiology/Immunology Development and Evaluation of a Terahertz Wave Imaging System for the Detection of Malignant and High-Risk Human Breast Lesions . James M. Ford, Medicine/Oncology; James Harris, Electrical Engineering Development of Integrated Optical Biosensors and Fluorescence Molecular Imaging Probes for Continuous Real-Time Monitoring of Stem Cells in Living Subjects .

Sanjiv Gambhir, Radiology; James Harris, Electrical Engineering Identification of Novel Therapeutic Targets in Melanoma by Genome-Wide Interference . Howard Chang, Neurology & Neurosciences; Aaron Straight, Biochemistry Investigation of Movement-Related Neural Activity from Premotor Cortex in Patients with Parkinson's Disease .

Jamie Henderson, Neurosurgery; Krishna Shenoy, Electrical Engineering Isolation and Characterization of Novel Hedgehog Antagonists for Therapy of Gastrointestinal Malignancies . James Chen, Molecular Pharmacology; George Fisher, Medicine/Oncology; Calvin Kuo, Medicine/Hematology Microfluidics Culture for the Mammalian Embryo.

Stephen Quake, Bioengineering; Mylene Yao, Obstetrics and Gynecology Monoclonal Antibody-Coated Ultra-Fine Iron Nanoparticles as Contrast Agents for Magnetic Resonance Imaging (MRI) of Tumors . Hongjie Dai, Chemistry; Robert J. Herfkens, Radiology; Lei Xing, Radiation Oncology Optimizing Microdialysis for Monitoring Organ Failure in the Intensive Care Setting .

Steven Alexander, Pediatrics; Harvey Cohen, Pediatrics; Joseph DiCarlo, Pediatrics; Paul Yock, Bioengineering Pharmacogenetics and Genomics of the IFOX Regimen in Colorectal Cancers . George Fisher, Medicine/Oncology; Robert Rouse, Pathology; Branimir Sikic, Medicine/Oncology; Robert Tibshirani, Health Research and Policy Phosphoprotein Signatures that Define the Therapeutic Efficacy of Atorvastatin for the Treatment of Lymphoma .

Dean Felsher, Medicine/Oncology; Garry Nolan, Microbiology & Immunology Proteomic Analysis of Immune Complexes in Rheumatoid Arthritis . Mark Genovese, Medicine; William Robinson, Medicine; Richard Zare, Chemistry; Curtis Frank, Chemical Engineering; Jeffrey Glenn, Medicine Role of Endothelial Cell Precursors in Tumor Response to Radiation . J.

Martin Brown, Radiation Oncology; Marlene Rabinovitch, Pediatrics Translating Hydrogel Technology into Novel Engineered Liver Tissues . Curtis Frank, Chemical Engineering; Jeffrey Glenn, Medicine Biofilm Development In Vivo: A Genetic Bioinformatic and Bioengineering Analysis . Gary K.

Schoolnik, Medicine/Infectious Diseases, Geographic Medicine; Alfred Spormann, Civil and Environmental Engineering Development for a Novel Cardiovascular Risk Factor . John P. Cooke, Medicine/Cardiovascular Disease; Richard Zare, Chemistry Development of Non-Flourescence-Based Detection Methods for Proteomics Studies: Carbon Nanotubes as Molecular Sensors .

Hongjie Dai, Chemistry; P. J. Utz, Medicine/Rheumatology and Immunology Lung Regeneration from Bone Marrow Stem Cells .

Christopher Contag, Pediatrics, Microbiology & Immunology, Radiology; Peter N. Kao, Medicine/Pulmonary and Critical Care Microfabricated Devices for Vascular Interventions . David Liang, Medicine/Cardiovascular Disease; Fritz Prinz, Mechanical Engineering Protein Profiling to Predict Breast Cancer After Radiation Therapy .

Gilbert Chu, Medicine/Oncology and Biochemistry; Robert Tibshirani, Biostatistics, Genetics; Dick Zare, Chemistry Rapid Color-Based Identification of Pathogenic Bacteria . Ellen Jo Baron, Pathology; Eric T. Kool, Chemistry Transplantation of Embryonic Stem Cell-Derived Islets in Diabetes Mellitus .

Seung Kim, Developmental Biology, Medicine; Judith Shizuru, Medicine/Bone Marrow Transplantation