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"The Genesis Mission: Transforming Science and Energy with AI (Phase I)" is currently closed and not accepting applications.
The Genesis Mission: Transforming Science and Energy with AI (Phase I) is sponsored by U.S. Department of Energy (DOE). The DOE is offering funding for research teams using artificial intelligence (AI) to tackle complex national scientific and energy challenges, including advanced manufacturing, biotechnology, critical materials, quantum information science, and nuclear energy.
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Opportunity Listing - The Genesis Mission: Transforming Science and Energy with AI The Genesis Mission: Transforming Science and Energy with AI Agency: Office of Science Assistance Listings: 81. 049 -- Office of Science Financial Assistance Program Last Updated: May 13, 2026 View version history on Grants.
gov DOE is soliciting new FY26 Phase I small team and Phase II large team applications in the following topic areas: advanced manufacturing, biotechnology, critical materials, nuclear fission, nuclear fusion, quantum information science, semiconductors and microelectronics, discovery science, and energy (see specific focus areas in Section III Program Descriptions).
In addition, this RFA will remain available to allow the recipients of FY26 Phase I awards to apply for larger team Phase II awards. In a few weeks, DOE plans to amend the RFA to clarify the LOI and application guidelines for FY26 Phase II awards.
In FY27, DOE plans to amend the RFA or to issue an alternative funding opportunity to update the topic and focus areas to allow a second competition of Phase I small team applications and Phase II large team applications. Grantor contact information GenesisMissionNOFO@science. doe.
gov GenesisMissionNOFO@science. doe. gov GenesisMissionNOFO@science.
doe. gov File name Description Last updated Genesis_Mission_Phase_I_Application_Template_v2. xlsx Phase I Application Template Apr 10, 2026 01:23 PM UTC Genesis_Mission_Phase_II_LOI_Template_v2.
xlsx Phase II LOI Template Apr 10, 2026 01:23 PM UTC Sample_OT_and_Project_Agreements_for_DE-FOA-0003612. pdf Sample OT and Project Agreements Mar 31, 2026 03:33 PM UTC Genesis_Mission_Phase_II_Application_Template. xlsx Phase II Application Template Apr 10, 2026 01:24 PM UTC DE-FOA-0003612.
000003. pdf DE-FOA-0003612 Apr 20, 2026 09:28 PM UTC Link to additional information Closing: December 17, 2026 Funding opportunity number : Cost sharing or matching requirement : Funding instrument type : Opportunity Category Explanation : Category of Funding Activity : Science technology and other research and development
According to the current listing, eligibility includes: Interdisciplinary teams from DOE National Laboratories, U. S. industry, and academia. Applicants may participate in multiple teams but may only serve as the lead organization on one proposal. Confirm the full requirements in the official notice before applying.
The current listing shows $500,000 to $750,000. Verify award ceilings, matching requirements, and allowable costs in the official notice.
The published deadline was April 28, 2026, which has passed. Check the official notice for any future application windows before investing time in a proposal.
The Genesis Mission: Transforming Science and Energy with AI (Phase I) is funded by U.S. Department of Energy (DOE). Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
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