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The Genesis Mission: Transforming Science and Energy with AI is sponsored by U.S. Department of Energy (DOE) Office of Basic Energy Sciences. This national initiative focuses on applying artificial intelligence to complex national challenges across science and energy systems, including advanced manufacturing, biotechnology, critical materials, nuclear energy, and quantum science.
It seeks to mobilize interdisciplinary teams to develop next-generation AI tools capable of addressing over 20 priority areas. The program aims to bridge gaps between scientific discovery and real-world application, structured in two phases to support both early-stage concepts and large-scale deployment.
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The Genesis Mission | Department of Energy A national initiative to build the world’s most powerful scientific platform. The Genesis Mission unites DOE National Labs, industry, academia, and more to harness AI for breakthroughs in energy dominance, discovery science, and national security. Inside the Genesis Mission The Genesis Mission is turning vision into action.
Building a national AI-for-science ecosystem. Advancing new partnerships. Developing cutting-edge capabilities.
All to accelerate scientific discovery. Addressing National Science and Technology Challenges in Key Areas The Genesis Mission includes national science and technology challenges that require accelerated U.S. innovation and discovery. Organized efforts around these challenges will deliver tangible benefits for the American people through the Genesis Mission’s AI platforms and partnerships.
American Science and Security Platform The American Science and Security Platform The Genesis Mission is building a complex integrated platform, connecting the world’s best supercomputers, experimental facilities, AI systems, and unique datasets.
Collaboration and Consortium Bringing Together World-Class Innovators The Genesis Mission brings together cross-sector and cross-functional leading experts to solve critical challenges at unprecedented speed. Learn More about Genesis Collaboration and Consortium U.S. Department of Energy Launches the Genesis Open Models Initiative – Apply Now!
U.S. Department of Energy Announces More Than $800 Million in Partner Commitments to the Genesis Mission Secretary of Energy Chris Wright Announces First Genesis Mission Projects Selected to Accelerate AI-Driven Scientific Discovery United States and Japan Announce Historic $1 Billion Partnership Under President Trump’s Genesis Mission From CSIS: Betting on America | Can AI Accelerate Scientific Discovery?
Featuring Under Secretary Darío Gil From PowerMag: The Genesis Mission: How AI Supercomputing Is About to Reshape American Science and Energy Energy Department Announces $293 Million in Funding to Support Genesis Mission National Science and Technology Challenges Energy Department Launches ‘Genesis Mission’ to Transform American Science and Innovation Through the AI Computing Revolution Get Genesis Mission updates from the Under Secretary for Science.
Explore the Genesis Mission Genesis Mission National Science and Technology Challenges The American Science and Security Platform Genesis Mission Collaboration Genesis Mission Resource Library Office of the Under Secretary for Science Get Genesis Mission Updates Follow Under Secretary Gil on LinkedIn Follow Under Secretary Gil on X
According to the current listing, eligibility includes: DOE National Laboratories, U.S. industry, and academia. Emphasis on collaborative, multi-institution teams. Federally affiliated entities are eligible to participate as team members, not subrecipients. Applicants may participate in multiple teams but can only lead one proposal. Confirm the full requirements in the official notice before applying.
The current listing shows $500,000 - $750,000 for Phase I; $6,000,000 - $15,000,000 for Phase II. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for The Genesis Mission: Transforming Science and Energy with AI are due December 17, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
The Genesis Mission: Transforming Science and Energy with AI is funded by U.S. Department of Energy (DOE) Office of Basic Energy Sciences. Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
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