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The Genesis Mission is sponsored by U.S. Department of Energy (DOE) Office of Technology Commercialization. This funding opportunity, part of the DOE's SBIR and STTR Phase I programs, is specifically aimed at small businesses to join the Genesis Mission.
It focuses on four areas: scaling biotechnology, leveraging AI for quantum computing and networking, designing materials with predictable functionality, and achieving AI-driven autonomous laboratories.
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Or search similar grants →According to the current listing, eligibility includes: Small businesses. Confirm the full requirements in the official notice before applying.
Applications for The Genesis Mission are due December 17, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
The Genesis Mission is funded by U.S. Department of Energy (DOE) Office of Technology Commercialization. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program
On July 22, 2026, the White House announced more than $5 billion in federal commitments for the Genesis Mission — the Department of Energy-led national initiative to fuse AI, exascale computing, and the 17 national labs into a single scientific platform. Nearly 300 projects across all 50 states were selected from a historic Request for Applications, and 15-plus agencies are now attaching funding to a set of National Science and Technology Challenges. Here is what the Genesis Mission is, how the money is structured, and the concrete on-ramps for researchers, universities, and small businesses who were not in the first cohort.
Read articleOn August 24, 2026, DOE and SBA signed a memorandum of agreement creating the Small Business Investment Company-Energy Initiative, pointing a $58 billion SBA-leveraged investment program at DOE's technology priorities. No application, no NOFO, no deadline. Here is how SBIC capital actually works, why a January 2026 rule change made this possible, and what a company sitting on a DOE Phase II award should do about it.
Read articleOn July 22, 2026 the White House committed more than $5 billion to expand the Genesis Mission — the government-wide 'AI for science' effort — announcing 278 first projects and 14 National Science and Technology Challenges spanning health, energy, infrastructure, manufacturing, and national security. More than 15 federal agencies are contributing awards, datasets, and facilities. Here is how the pieces fit, why it reorganizes the science-funding map, and how to position for the awards flowing out of it.
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