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Advancing the Use of 3D Technologies Using Human Auditory, Vestibular and Chemosensory Organoids to Create New Approach Models (NAMs) for Treatments is sponsored by NIH Office of Research on Women's Health (ORWH). This highlighted NIH topic encourages collaborative research combining human organoids with 3D technologies, such as bioprinting and AI-facilitated data-driven in silico platforms.
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Advancing the Use of 3D Technologies Using Human Auditory, Vestibular and Chemosensory Organoids to Create New Approach Models (NAMs) for Treatments | Grants & Funding U.S. Department of Health and Human Services National Institutes of Health Advancing the Use of 3D Technologies Using Human Auditory, Vestibular and Chemosensory Organoids to Create New Approach Models (NAMs) for Treatments When beginning your next investigator-initiated application, consider the following NIH highlighted topic.
The area of science described below is of interest to the listed NIH Institutes, Centers, and Offices (ICOs). This is not a notice of funding opportunity (NOFO). Apply through an appropriate NIH Parent Funding Announcement or another broad NIH opportunity available on Grants.
gov . Learn how to interpret and use Highlighted Topics . Post Date: December 2, 2025 Expiration Date: December 2, 2027 The auditory, vestibular, and chemosensory systems are elaborate cellular ecosystems and while molecular research has made significant strides in biological advancements, faster timelines for effective molecular therapeutic deliverables remain a challenge.
Contributing to these challenges are the lack of advanced model systems that improve cell system mimicry and facilitate increased throughputs.
The purpose of this highlighted topic is to encourage collaborative research efforts combining the use of human auditory, vestibular, and chemosensory organoids, with 3D technologies, such as bioprinting, creation of biolinks and tissue replicates, and AI facilitated data driven in silico platforms. Such research efforts will expedite faster and more accurate treatments and therapeutics for disease and disorders.
With the advancement of iPSC technologies, personalized human organoid research holds increased promise when combined with other ex vivo assessment platforms to rapidly advance precision medicine approaches. These NAMs require post-development characterization to provide accurate functional cell mimicry and recapitulation of the native correlative biological function.
Applications focused on improvement of reproducibility and stability are highly encouraged. Taken together, these new and combined approaches could provide faster and increased accuracy of cellular platforms and accelerate the development of clinical deliverables. Central Scientific Contact: Nancy Freeman, Ph.
D. ; Auditory and Vestibular Susan Sullivan, Ph. D.
; Chemosenses National Institute on Deafness and Other Communication Disorders (NIDCD) Nancy Freeman, Ph. D. (Auditory and Vestibular) Susan Sullivan, Ph.
D. (Chemosenses) Office of Research on Women's Health (ORWH) The NIH Office of Research on Women's Health (ORWH) interests include: AI-driven in silico platforms and advanced 3D technologies to develop sex-specific human auditory, vestibular, and chemosensory organoid models to expedite the development of molecular therapeutic deliverables to treat diseases and disorders that uniquely or disproportionately affect women.
Creation of NAMs with accurate functional cell mimicry with improved reproducibility and stability, while investigating the functional impact of sex differences and hormonal levels across various life stages to advance rigor and reproducibility to accelerate personalized medicine related to women’s health.
Advancement of iPSC technologies and personalized human organoid research to accelerate precision medicine, which addresses unique biological and hormonal influences in women's health. ORWH does not award grants. Applications must be relevant to at least one participating NIH Institute or Center’s objectives.
Elena Gorodetsky, M. D. , Ph.
D. Victoria Shanmugam, MBBS, MRCP, FACR, CCD For technical issues E-mail OER Webmaster
According to the current listing, eligibility includes: This is a highlighted topic, not a specific NOFO. Applications should be submitted through appropriate NIH Parent Funding Announcements or other broad NIH opportunities. Confirm the full requirements in the official notice before applying.
Applications for Advancing the Use of 3D Technologies Using Human Auditory, Vestibular and Chemosensory Organoids to Create New Approach Models (NAMs) for Treatments are due December 2, 2027. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Advancing the Use of 3D Technologies Using Human Auditory, Vestibular and Chemosensory Organoids to Create New Approach Models (NAMs) for Treatments is funded by NIH Office of Research on Women's Health (ORWH). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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