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Continuation of Solicitation for the Office of Science Financial Assistance Program (Open Call) is sponsored by U.S. Department of Energy (DOE) Office of Science (SC). Requests research proposals for most of its program areas. The research areas of interest for the corresponding fiscal year will be described within the BER section of the Open Call.
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GRANTS Open FOAs | U.S. DOE Office of Science (SC) For assistance with the Office of Science's Portfolio Analysis and Management System (PAMS) at https://pamspublic. science. energy.
gov , please contact the Helpdesk at (855) 818-1846 (toll-free), (301) 903-9610, or sc. pams-helpdesk@science. doe.
gov .
Search Phrase Select Program Select Program Accelerator R&D and Production Advanced Scientific Computing Research Biological and Environmental Research Isotope R&D and Production Small Business Innovation Research and Small Business Technology Transfer Workforce Development for Teachers and Scientists Funding for Accelerated, Inclusive Research Reaching a New Energy Sciences Workforce Select Fiscal Year Select Fiscal Year The Genesis Mission: Transforming Science and Energy with AI DE-FOA-0003612 (updated April 20, 2026) Submission Deadline for FY26 Phase I Applications: May 1, 2026, at 11:59 PM Eastern (grants.
gov) Submission Deadline for FY26 Phase II Letters of Intent: May 1, 2026, at 5 PM Eastern (PAMS) Submission Deadline for FY26 Phase II Applications: May 19, 2026, at 11:59 PM Eastern (grants. gov) Submission Deadline for Phase II Applications resulting from FY26 Phase I Awards: December 17, 2026, at 11:59 PM Eastern (grants. gov) A Phase I Application Template is available here .
A Phase II Letter of Intent Template is available here. A Phase II Application Template is available here. Sample OT and Project Agreements are available here.
A document of Frequently Asked Questions is provided (updated April 27, 2026). Genesis Mission: Informational Webinars FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program A Pre-Application is optional/encouraged. A Pre-Application may be required for consideration by certain review panels.
U.S. Department of Energy SC-43/Germantown Building 1000 Independence Ave. , SW sc. grantsandcontracts@doe.
gov Leaving Office of Science The link you have requested will take you to a website outside the Office of Science. Please click the following link to continue: Thank you for visiting our site. We hope your visit was informative and enjoyable.
According to the current listing, eligibility includes: Colleges and universities, non-profit and for-profit research organizations, DOE's national laboratories, small businesses, and other federal research organizations. Confirm the full requirements in the official notice before applying.
Applications for Continuation of Solicitation for the Office of Science Financial Assistance Program (Open Call) are due September 30, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Continuation of Solicitation for the Office of Science Financial Assistance Program (Open Call) is funded by U.S. Department of Energy (DOE) Office of Science (SC). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
The Trump administration committed $5B and 278 projects across 15+ agencies to the Genesis Mission. Here's the structure — and how to position for the next wave.
Read articleOn July 22, 2026, the White House announced more than $5 billion in federal commitments for the Genesis Mission — the Department of Energy-led national initiative to fuse AI, exascale computing, and the 17 national labs into a single scientific platform. Nearly 300 projects across all 50 states were selected from a historic Request for Applications, and 15-plus agencies are now attaching funding to a set of National Science and Technology Challenges. Here is what the Genesis Mission is, how the money is structured, and the concrete on-ramps for researchers, universities, and small businesses who were not in the first cohort.
Read articleDOE's FY2026 Office of Science open-call solicitation (DE-FOA-0003600) makes roughly $500 million available across about 500 awards of $50,000 to $5 million — across computing, physics, chemistry, biology, fusion, and isotopes — with a rolling window that stays open through September 30, 2026. Unlike a targeted NOFO, it lets investigators propose almost anything within the agency's mission. Here is how the open call actually works, why it is chronically underused, and how to write into it.
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