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DE-FOA-0003612 The Genesis Mission: Transforming Science and Energy with AI is a grant from the U.S. Department of Energy (DOE) Office of Science that funds AI-driven research across strategic science and energy topic areas.
DOE is soliciting FY26 Phase I small team and Phase II large team applications covering advanced manufacturing, biotechnology, critical materials, nuclear fission, nuclear fusion, quantum information science, semiconductors and microelectronics, discovery science, and energy.
Eligible applicants include colleges and universities, non-profit and for-profit research organizations, DOE national laboratories, small businesses, and other federal research organizations. The deadline is December 17, 2026.
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Opportunity Listing - The Genesis Mission: Transforming Science and Energy with AI The Genesis Mission: Transforming Science and Energy with AI Agency: Office of Science Assistance Listings: 81. 049 -- Office of Science Financial Assistance Program Last Updated: April 10, 2026 View version history on Grants.
gov DOE is soliciting new FY26 Phase I small team and Phase II large team applications in the following topic areas: advanced manufacturing, biotechnology, critical materials, nuclear fission, nuclear fusion, quantum information science, semiconductors and microelectronics, discovery science, and energy (see specific focus areas in Section III Program Descriptions).
In addition, this RFA will remain available to allow the recipients of FY26 Phase I awards to apply for larger team Phase II awards. In a few weeks, DOE plans to amend the RFA to clarify the LOI and application guidelines for FY26 Phase II awards.
In FY27, DOE plans to amend the RFA or to issue an alternative funding opportunity to update the topic and focus areas to allow a second competition of Phase I small team applications and Phase II large team applications. Grantor contact information GenesisMissionNOFO@science. doe.
gov GenesisMissionNOFO@science. doe. gov GenesisMissionNOFO@science.
doe. gov File name Description Last updated Genesis_Mission_Phase_I_Application_Template_v2. xlsx Phase I Application Template Apr 10, 2026 01:23 PM UTC Genesis_Mission_Phase_II_LOI_Template_v2.
xlsx Phase II LOI Template Apr 10, 2026 01:23 PM UTC Sample_OT_and_Project_Agreements_for_DE-FOA-0003612. pdf Sample OT and Project Agreements Mar 31, 2026 03:33 PM UTC Genesis_Mission_Phase_II_Application_Template. xlsx Phase II Application Template Apr 10, 2026 01:24 PM UTC DE-FOA-0003612.
000003. pdf DE-FOA-0003612 Apr 20, 2026 09:28 PM UTC Link to additional information Closing: December 17, 2026 Funding opportunity number : Cost sharing or matching requirement : Funding instrument type : Opportunity Category Explanation : Category of Funding Activity : Science technology and other research and development
According to the current listing, eligibility includes: May be open to one or more institution types, including colleges and universities, non-profit and for-profit research organizations, DOE's national laboratories, small businesses, and other federal research organization…. Confirm the full requirements in the official notice before applying.
Applications for DE-FOA-0003612 The Genesis Mission: Transforming Science and Energy with AI are due December 17, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
DE-FOA-0003612 The Genesis Mission: Transforming Science and Energy with AI is funded by U.S. Department of Energy (DOE) Office of Science (SC). Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
FY2026 Continuation of Solicitation for the Office of Science Financial Assistance Program is sponsored by U.S. Department of Energy (DOE) Office of Science (SC). This is an 'Open Call' for research proposals across most program areas within the DOE's Office of Science, including those relevant to climate change and renewable energy, and basic energy sciences.
FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program is sponsored by U.S. Department of Energy (DOE) Office of Science (SC). The DOE Office of Science is accepting applications for research across various program areas, including Fusion Energy Sciences. This is an annual open solicitation for research within SC's congressionally authorized mission.
NVIDIA Graduate Fellowship Program is a grant from NVIDIA providing up to $60,000 per award to PhD students conducting research that advances accelerated computing and its applications. Now in its 25th year, the program invites nominations from doctoral students pushing the boundaries of artificial intelligence, robotics, autonomous vehicles, and related fields. Recipients receive not only research funding but also access to NVIDIA technology, products, and engineering expertise, along with a mandatory in-person summer internship. Students are nominated by their faculty advisors and selected based on academic achievement and research area alignment.
CalSEED Concept Award is a grant from the California Energy Commission that provides $150,000 in funding to early-stage clean energy innovators in California. The program targets individuals, businesses, and nonprofits developing hardware, software, or integrated solutions at Technology Readiness Levels 2-4. Eligible technology areas rotate each cycle and have included battery recycling and reuse, long-duration energy storage, medium- and heavy-duty vehicle electrification, industrial electrification, and advanced EV charging. Applicants must be located in California, have under $1 million in private funding, and propose innovations that benefit California ratepayers. Concept Award winners also receive professional development resources and access to accelerator programs, and may compete for a subsequent $450,000 Prototype Award.
The Trump administration committed $5B and 278 projects across 15+ agencies to the Genesis Mission. Here's the structure — and how to position for the next wave.
Read articleOn July 22, 2026, the White House announced more than $5 billion in federal commitments for the Genesis Mission — the Department of Energy-led national initiative to fuse AI, exascale computing, and the 17 national labs into a single scientific platform. Nearly 300 projects across all 50 states were selected from a historic Request for Applications, and 15-plus agencies are now attaching funding to a set of National Science and Technology Challenges. Here is what the Genesis Mission is, how the money is structured, and the concrete on-ramps for researchers, universities, and small businesses who were not in the first cohort.
Read articleDOE's FY2026 Office of Science open-call solicitation (DE-FOA-0003600) makes roughly $500 million available across about 500 awards of $50,000 to $5 million — across computing, physics, chemistry, biology, fusion, and isotopes — with a rolling window that stays open through September 30, 2026. Unlike a targeted NOFO, it lets investigators propose almost anything within the agency's mission. Here is how the open call actually works, why it is chronically underused, and how to write into it.
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