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Find similar grantsGenesis Mission National Science and Technology Challenges is sponsored by Department of Energy (DOE) Office of Science. Seeks applications from interdisciplinary teams addressing the Genesis Mission National Science and Technology Challenges to accelerate scientific discovery and R&D workflows using novel AI models and frameworks.
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The Genesis Mission | Department of Energy A national initiative building the world's most powerful scientific platform. The Genesis Mission unites DOE National Labs, industry, academia, and more to harness AI for breakthroughs in energy dominance, discovery science, and national security. Inside the Genesis Mission The Genesis Mission is turning vision into action.
Building a national AI-for-science ecosystem. Advancing new partnerships. Developing cutting-edge capabilities.
All to accelerate scientific discovery. Addressing National Science and Technology Challenges in Key Areas The Genesis Mission includes national science and technology challenges that require accelerated U.S. innovation and discovery. Organized efforts around these challenges will deliver tangible benefits for the American people through the Genesis Mission’s AI platforms and partnerships.
American Science and Security Platform The American Science and Security Platform The Genesis Mission is building a complex integrated platform, connecting the world’s best supercomputers, experimental facilities, AI systems, and unique datasets.
Collaboration and Consortium Bringing Together World-Class Innovators The Genesis Mission brings together cross-sector and cross-functional leading experts to solve critical challenges at unprecedented speed. Learn More about Genesis Collaboration and Consortium U.S. Department of Energy Launches the Genesis Open Models Initiative – Apply Now!
U.S. Department of Energy Announces More Than $800 Million in Partner Commitments to the Genesis Mission Secretary of Energy Chris Wright Announces First Genesis Mission Projects Selected to Accelerate AI-Driven Scientific Discovery United States and Japan Announce Historic $1 Billion Partnership Under President Trump’s Genesis Mission From CSIS: Betting on America | Can AI Accelerate Scientific Discovery?
Featuring Under Secretary Darío Gil From PowerMag: The Genesis Mission: How AI Supercomputing Is About to Reshape American Science and Energy Energy Department Announces $293 Million in Funding to Support Genesis Mission National Science and Technology Challenges Energy Department Launches ‘Genesis Mission’ to Transform American Science and Innovation Through the AI Computing Revolution Get Genesis Mission updates from the Under Secretary for Science.
Explore the Genesis Mission Genesis Mission National Science and Technology Challenges The American Science and Security Platform Genesis Mission Collaboration Genesis Mission Resource Library Office of the Under Secretary for Science Get Genesis Mission Updates Follow Under Secretary Gil on LinkedIn Follow Under Secretary Gil on X
According to the current listing, eligibility includes: Unrestricted; open to any type of entity. Confirm the full requirements in the official notice before applying.
The current listing shows $500,000 - $16,000,000. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for Genesis Mission National Science and Technology Challenges are due December 17, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Genesis Mission National Science and Technology Challenges is funded by Department of Energy (DOE) Office of Science. Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
The Trump administration committed $5B and 278 projects across 15+ agencies to the Genesis Mission. Here's the structure — and how to position for the next wave.
Read articleOn July 22, 2026, the White House announced more than $5 billion in federal commitments for the Genesis Mission — the Department of Energy-led national initiative to fuse AI, exascale computing, and the 17 national labs into a single scientific platform. Nearly 300 projects across all 50 states were selected from a historic Request for Applications, and 15-plus agencies are now attaching funding to a set of National Science and Technology Challenges. Here is what the Genesis Mission is, how the money is structured, and the concrete on-ramps for researchers, universities, and small businesses who were not in the first cohort.
Read articleDOE's FY2026 Office of Science open-call solicitation (DE-FOA-0003600) makes roughly $500 million available across about 500 awards of $50,000 to $5 million — across computing, physics, chemistry, biology, fusion, and isotopes — with a rolling window that stays open through September 30, 2026. Unlike a targeted NOFO, it lets investigators propose almost anything within the agency's mission. Here is how the open call actually works, why it is chronically underused, and how to write into it.
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