Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions (G11 Clinical Trials Not Allowed)

Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions (G11 Clinical Trials Not Allowed) is sponsored by NIH Fogarty International Center. The program's goal is to strengthen the scientific capacity of institutions in low- and middle-income countries (LMICs) by enhancing functional resources for HIV research. It encourages collaborative applications from U.

Expired PAR-16-280: Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions (G11) This notice has expired. Check the NIH Guide for active opportunities and notices. Department of Health and Human Services Part 1.

Overview Information Participating Organization(s) National Institutes of Health ( NIH ) of Participating Organizations Fogarty International Center ( FIC ) National Institute on Alcohol Abuse and Alcoholism ( NIAAA ) National Institute on Drug Abuse ( NIDA ) Funding Opportunity Title Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Associate Research Development Award (EARDA) May 14, 2019 - This PA has been reissued as PAR-19-285 .

Reminder: FORMS-E Grant Application Forms and Instructions Must be Used for Due Dates On or After January 25, 2018. - Updates to Active Funding Opportunity Announcements to Prepare for Policy Changes Impacting Due Dates On or After January 25, 2018. May 10, 2017 - New NIH "FORMS-E" Grant Application Forms and Instructions Coming for Due Dates On or After January 25, 2018.

See NOT-OD-17-062 . Funding Opportunity Announcement (FOA) Number Companion Funding Opportunity PAR-18-717 D43 International Research Training Grants PAR-16-281 D71 International Research Training Planning Grants PAR-16-279 D43 International Research Training Grants Additional Information on Eligibility .

Catalog of Federal Domestic Assistance (CFDA) Number(s) Funding Opportunity Purpose The overall goal of the Fogarty International Center (FIC) HIV Research Training Program is to strengthen the scientific capacity of institutions in low- and middle-income countries (LMICs) to conduct HIV research on the evolving HIV epidemic in their countries.

This FOA encourages collaborative applications from U.S. and LMIC institutions to support training to achieve technical, administration and financial management expertise required for one of the six research infrastructure functions considered critical to a successful high quality Research administration and management; Research integrity oversight; Ethical review of research for the protection of human Laboratory animal welfare oversight Health sciences library and information services; and Information and communications technology systems (ICT) for Research infrastructure training programs will maximize previous investments and further strengthen the LMIC institution's research capabilities, and provide more accessible research infrastructure training opportunities to others in their own country and in other LMICs.

Open Date (Earliest Submission Date) Letter of Intent Due Date(s) 30 days prior to the application due date August 25, 2016; August 23, 2017; August 23, 2018, by 5:00 PM local time of applicant organization. All types of applications allowed for this funding opportunity announcement are due on these dates.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date. AIDS Application Due Date(s) August 25, 2016; August 23, 2017; August 23, 2018, by 5:00 PM local time of applicant organization. All types of applications allowed for this funding opportunity announcement are due on these dates.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

October 2016, October 2017, October 2018 January 2017, January 2018, January 2019 April 2017, April 2018, April 2019 Required Application Instructions It is critical that applicants follow the instructions in (R&R) Application Guide , except where instructed to do otherwise (in this FOA or in a Notice from the NIH Guide for Grants and Contracts ).

Conformance to all requirements (both in the Application Guide and the FOA) is required and strictly enforced. Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV . When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions.

Applications that do not comply with these instructions may be delayed or not accepted for review. Part 1. Overview Information Part 2.

Full Text of the Announcement I. Funding Opportunity Description Section II. Award Information Section III.

Eligibility Information Section IV. Application and Submission Section V. Application Review Information Section VI.

Award Administration Information Section VII. Agency Contacts Section VIII. Other Information Full Text of Announcement Section I.

Funding Opportunity Description The overall goal of the Fogarty International Center (FIC) HIV Research Training Program is to strengthen the scientific capacity of institutions in low- and middle-income countries (LMICs) to conduct HIV research related to the evolving HIV epidemic in their country. The Fogarty HIV Research Training Program currently invites applications under three different Funding Opportunity Announcements (FOAs).

This FOA (G11) encourages applications for infrastructure development training programs to strengthen one of the six infrastructure functions critical to support HIV research at LMIC institutions. Applicants interested in scientific research training should consult D43 FOA ( PAR-16-279 ). A third FOA (D71), ( PAR-16-281 ), provides the option for a planning grant to LMIC institutions prior to an application for the research training.

This FOA complements the other two FOAs in the Fogarty HIV Research Training Program, which are focused on scientific research training, by supporting training that addresses six research infrastructure functions considered critical to successful high quality research.

Research infrastructure training programs will maximize previous investments and further strengthen the LMIC institution's research capabilities, and provide more accessible research infrastructure training opportunities to others in their own country and in other LMICs.

This FOA supports training related to technical expertise, administration and management limited to these six functions: administration and management - The general business management practices common to the administration of all grants, such as financial accountability, reporting, equipment management, and retention of records.

These include the development and implementation of standard operating procedures for tracking grant expenditures and compliance with NIH and other donor funding policies during pre and post-award periods.

integrity oversight - Administrative processes in place at an institution to promote research integrity , and to handle allegations of research misconduct among its leadership, faculty, investigators, trainees, and review of research for the protection of human subjects - An institutional system that reviews proposed research, using a framework based on established, internationally recognized ethical principles, to safeguard the rights and welfare of individuals who participate as subjects in research activities.

animal welfare oversight - An institutional system that addresses the humane use of animals in research, using a framework based on established internationally recognized guiding principles for biomedical research involving animals .

sciences library and information services - Print collection and electronic information resources on a wide range of health science topics that are organized by an institution as a service to its researchers, faculty, and communications technology systems (ICT) for research - Computer systems that provide, coordinate, and manage information technology, and advance computational science.

In previous competitions of this program, LMIC institutions were not eligible to apply to the G11 FOA, but this restriction is now lifted. Another change is that the beneficiary of the training supported through this G11 FOA is expanded to include an LMIC institution that is a site in an established HIV research network.

FIC, with co-funding from other NIH Institutes, Centers and Offices (I/C/O), provided almost 30 years of support to enhance HIV research through HIV research training programs. Awards supported research training of LMIC scientists who participated in important HIV research conducted at LMIC institutions in partnership with U.S. and other international scientists and scientific institutions.

Over the years, some of the most important recent scientific advances in HIV/AIDS, including interventions to reduce mother-to-child HIV transmission, address HIV/TB co-infection, and prevent HIV infection through behavior change, microbicides, and antiretroviral drugs, were facilitated through partnerships with LMIC scientists and supported by the FIC research training programs.

Continued investment in training to strengthen research at LMIC institutions is needed to address the on-going HIV epidemic and to achieve the goals of a "Cure" and an "AIDS-Free Efforts to implement research findings in the context of increased HIV prevention, care and treatment services in LMICs over the past ten years led to the emergence of new issues, such as how to best combine HIV prevention interventions, link newly diagnosed individuals into care programs, and integrate HIV programs with other health services.

As LMICs implement HIV prevention, care and treatment programs, these and other, yet undefined, issues will need evidence-based solutions.

The social context of an LMIC influences the design of research to answer many of these evolving HIV research questions, therefore LMIC institutions and researchers are best positioned to conduct the most relevant HIV research, disseminate the results in-country, and influence policymakers, program managers and medical/public health practice.

In the Fogarty HIV Research Training Program, each research training award is expected to focus on strengthening specific high priority HIV research capacity at an identified LMIC institution or at LMIC sites within an established HIV research network.

An established HIV Research Network (referred to as "the Network" in these FOAS) is defined as multiple research institutions, with a group of researchers from each institution that are collaboratively working towards a common HIV research agenda, that are formally organized and funded for such collaboration. This FOA will not support the establishment of a new HIV Research Network.

The network sites located in LMICs for an established HIV research network are referred to as "LMIC Network sites" in these FOAs.

The Fogarty HIV Research Training Program is designed to move beyond simple output indicators (number and type of people trained) to outcome indicators (increased research capacity at an LMIC institutional or at LMIC Network site(s) level) to provide more meaningful monitoring and evaluation of individual awards and of the program as a whole. This program FOA provides opportunities for a U.

S or LMIC institution to collaborate with their partners, including an established HIV Research Network with LMIC sites, to fill gaps in training in a particular research infrastructure function that will strengthen the HIV research capacity at the proposed LMIC institution.

Applicants should design training programs for LMIC scientists and staff at LMIC institution so that trainees can strengthen the selected research infrastructure function at the LMIC institution. If the LMIC institution is a LMIC Network site, the training should strengthen the selected function at the institutional level and not focus solely at the network site level.

This approach will allow applicants to be more responsive to research needs at an LMIC institution(s) and enhance the capacity for LMIC institutions to collaborate with NIH, U. S. Government, other donors and LMICs in their HIV/AIDS efforts.

The selected infrastructure function may need expertise that crosses disciplines. Applicants are encouraged to develop programs that include training in all disciplines needed to address the selected infrastructure function. The training proposed is expected to raise the LMIC institution to the next level of capacity in the selected infrastructure function.

In many cases, it is anticipated that the proposed program will complement ongoing efforts to strengthen the infrastructure function at the LMIC institution(s) and, if relevant, as an LMIC Network site. Proposed training should be designed to be synergistic and not duplicative of these It is anticipated that some LMIC institutions could serve as training sites in the selected infrastructure function for other LMIC institutions.

Faculty and staff from these more advanced LMIC institutions may serve as training faculty.

As a result, three different scenarios for applications may be proposed: a U.S. institution as the applicant with an LMIC institution as beneficiary of the training; a LMIC institution as applicant with their own institution as the beneficiary of the training to further strengthen its own capacity; a LMIC institution as applicant with another LMIC institution as the beneficiary of the training.

Proposed programs can support a combination of short- (three months or less), medium- (over three months and up to six months) and long- (six months and longer) term training to support increased capacity in the specified infrastructure function at the LMIC institution.

Emphasis should be given to training that provides the theoretical and applied depth needed by an individual or by a group of individuals in the LMIC institution to sustain the higher level of capacity in the selected infrastructure function after the three-year training period. Training models may be innovative, but must be appropriate to the context of the LMIC institution. Training should take place at the most appropriate site.

Training sites may be proposed at institutions other than the applicant or LMIC institution named in the application, including those in high-income countries. Innovative approaches, topics for training, practicum experiences, collaborative exchanges, leadership training, organizational planning, career development planning, and mediation/negotiation training, are encouraged.

Distance learning with sufficient mentoring and support at the LMIC institution may be proposed. Training-related projects must be conducted at or involve data from the LMIC institution or, if relevant, from LMIC Network sites, identified in the application. Applicants are encouraged to review the NIH HIV/AIDS Research Priorities , the NIH Plan for HIV-Related Research for the year they are applying, available at http://www.

oar. nih. gov/strategicplan , Asked Questions for the Fogarty HIV Research Training for more information.

See Section VIII. Other Information for award authorities Grant: A support mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.

Application Types Allowed Glossary and the SF424 (R&R) Application Guide provide details on Clinical Trials Not Allowed for due dates on or after January 25, 2018: Only accepting applications that do not propose clinical trials Need help determining whether you are doing a clinical trial?

Funds Available and Anticipated Number of Awards The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. Application budgets are limited to $92,000 direct costs per year exclusive of consortium indirect The maximum project period is 3 years. Grants Policy Statement will apply to the applications submitted and awards made in response to this FOA.

Higher Education Institutions Public/State Controlled Institutions of Higher Education Private Institutions of Higher Education The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education: Hispanic-serving Institutions Historically Black Colleges and Universities (HBCUs) Nonprofits Other Than Institutions of Higher Education Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Nonprofits without 501(c)(3) IRS Status (Other than Institutions Non-domestic (non-U.S.) Entities (Foreign Institutions) in LMICs An application may be submitted by a foreign institution in a low- or middle-income country (LMIC) or by a domestic (U.S.) institution that demonstrates active HIV research collaborations with the LMIC institution named in the application.

Collaboration should be documented by joint publications, grants or previous research training activities. The applicant institution must have a strong and high quality program in the research infrastructure function proposed under this FOA and must have the requisite training staff and facilities to conduct the proposed training program.

LMICs are defined by the World Bank classification system (according to Gross National Income (GNI) per capita as low-income, lower-middle-income, and upper-middle-income ( http://data. worldbank. org/about/country-classifications/country-and-lending-groups ).

Other High Income Country (HIC) Faculty and institutions may be named as partners and serve as training sites. Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible Foreign components, as defined in the NIH Grants Policy Statement , are allowed.

Applicant organizations must complete and maintain the following registrations as described in the SF 424 (R&R) Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted.

Registration can take 6 weeks or more, so applicants should begin the registration process as soon as Policy on Late Submission of Grant Applications states that failure to complete registrations in advance of a due date is not a valid reason for a Universal Numbering System (DUNS) - All registrations require that applicants be issued a DUNS number.

After obtaining a DUNS number, applicants can begin both SAM and eRA Commons registrations. The same DUNS number must be used for all registrations, as well as on the grant application. System for Award Management (SAM) (formerly CCR) Applicants must complete and maintain an active registration, which requires renewal at least annually .

The renewal process may require as much time as the initial registration. SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code. Commercial and Government Entity (NCAGE) Code Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM.

must have an active DUNS number and SAM registration in order to complete the eRA Commons registration. Organizations can register with the eRA Commons as they are working through their SAM or Grants. gov registration.

eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an must have an active DUNS number and SAM registration in order to complete the International applicants may obtain more information on the registrations required for grants. gov and eRA Commons at: https://grants. nih.

gov/grants/ElectronicReceipt/files/Tips_for_International_Applicants. pdf . https://grants.

nih. gov/grants/ElectronicReceipt/files/international_support. pdf https://grants.

nih. gov/grants/ElectronicReceipt/files/international_qa. pdf https://grants.

nih. gov/grants/ElectronicReceipt/preparing_grantsgov_reg. htm Guidance for International Applicants Blocked from Registration Websites: NOT-OD-11-090 .

An NIH supported webinar on Electronic Submission of Grant Applications for Foreign Institutions can be found at https://grants. nih. gov/grants/webinar_docs/webinar_20120927.

htm . Directors/Principal Investigators (PD(s)/PI(s)) All PD(s)/PI(s) must have an eRA Commons account. PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons.

If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining an eRA Commons account can take up to 2 weeks.

Eligible Individuals (Program Director/Principal Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed infrastructure training program as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to develop an application for support.

Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.

For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the SF424 The PD(s)/PI(s) should be an established expert in the research infrastructure function in which the application is targeted and capable of providing both administrative and professional leadership to the development and implementation of the proposed training.

The PD(s)/PI(s) should have experience in supporting high priority HIV research and be knowledgeable of the infrastructure needs of the LMIC institution. The PD(s)/PI(s) will be expected to monitor and assess the program and submit all documents and reports as required.

The PD(s)/PI(s) is responsible for appointing members of the Training Advisory Committee (TAC) and for establishing a structure to obtain regular Applicants are encouraged to include LMIC individuals who meet the eligibility requirement as a Multiple PD/PI (see https://grants. nih. gov/grants/multi_pi/ for more information).

This FOA does not require cost sharing as defined in the NIH Grants Policy Statement . 3. Additional Information on Eligibility Applicant organizations may submit more than one application, provided that each application is scientifically distinct.

The NIH will not accept duplicate or highly overlapping applications under review at the same time. This means that the NIH will A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application.

An application that has substantial overlap with another application pending appeal of initial peer review (see NOT-OD-11-101 ). Proposed training staff and mentors should have expertise and experience relevant to the proposed training program. Mentors must be committed to continue their involvement throughout the total period of the mentee’s participation in this award.

Only LMIC individuals who are or are expected to be associated with that LMIC institution are eligible for training under this FOA. Individuals who also have citizenship or permanent residency in the U.S. or other high income countries are not eligible for support under this FOA. Section IV.

Application and Submission Information Applicants must obtain the SF424 (R&R) application package associated with this funding opportunity using the Apply for Grant Electronically button in this FOA or following the directions provided at Grants. gov . 2.

Content and Form of Application Submission It is critical that applicants follow the instructions in (R&R) Application Guide , including Supplemental Grant Application Instructions except where instructed in this funding opportunity announcement to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced.

Applications that are out of compliance with these instructions may be delayed or not accepted for For information on Application Submission and Receipt, visit Frequently Asked Questions Application Guide, Electronic Submission of Grant Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows IC staff to estimate the potential review workload and By the date listed in Part 1.

Overview Information , prospective applicants are asked to submit a letter of intent that includes the following information: Descriptive title of proposed activity Name(s), address(es), and telephone number(s) of the PD(s)/PI(s) Names of other key personnel Participating institution(s) Number and title of this funding opportunity The letter of intent should be sent to: All page limitations described in the SF424 Application Guide and the Table of Page Instructions for Application Submission The following section supplements the instructions found in the SF424 (R&R) Application Guide and should be used for preparing an All instructions in the SF424 (R&R) Application Guide SF424(R&R) Project/Performance Site Locations All instructions in the SF424 (R&R) Application Guide must be followed.

Include the applicant institution, the LMIC institution or LMIC Network sites, and any other participating institutions, both U.S. and foreign as performance sites.

SF424(R&R) Other Project Information All instructions in the SF424 (R&R) Application Guide must be followed with the following modifications: Summary/Abstract : Provide an abstract of the entire application, including the long-term goals and objectives of the program, key elements of the training plan, and a brief description of the planned training program.

Include the name(s) of the LMIC(s), and the name of the in-country institution, and, if relevant, the names of the Network and the Network site at the LMIC institution. Identify the research infrastructure function for which training is proposed, and how the increased capacity will strengthen the high priority HIV research capacity at the LMIC institution.

Include the rationale and design of the program, the expected increased capacity in the infrastructure function and the measures the applicant will use to demonstrate the increased infrastructure Narrative : Include the selected research infrastructure function for which training is proposed, and how this addresses the HIV research priorities identified by NIH as "high ."

Include the LMIC and name of the in-country institution and, if relevant, the names of the Network and the Network site at the LMIC institution. Describe the public health relevance of the strengthened infrastructure support to the HIV research enterprise that will be supported at the LMIC institution. Committee: A Training Advisory Committee (TAC) is required for this grant.

A description of the responsibilities, frequency of meetings, and other relevant information should be included. Describe the composition of the TAC, identifying the role and the desired expertise of members.

The TAC should include expert faculty and staff in the research infrastructure function proposed and persons with experience in training and mentoring LMIC staff or supporting HIV research at the LMIC institution and, if relevant, LMIC Network sites. TAC members can be from the LMICs, U.S., or other countries. Describe how the TAC will provide feedback and advice to the PD(s)/PI(s) in the implementation of the training program.

They should be included as key personnel as described in SF 424(R&R) Senior/Key Person Profile Expanded Component. Please name your file Advisory_Committee. pdf .

filename provided for each Other Attachment will be the name used for the bookmark in the electronic application in eRA Commons. SF424(R&R) Senior/Key Person Profile All instructions in the SF424 (R&R) Application Guide must be followed.

In addition: The qualifications and experience, including relevant scientific or professional background and relevant training experience in LMICs, of the proposed PI(s)/PD(s) to lead the proposed training program should be described For applications from U.S. institutions, include the name of one person at the LMIC institution who will serve as the main collaborator(s), select Other, and list their role as Key Collaborator.

Include at least ONE person at all of the other U.S. and foreign participating institutions as senior/Key Personnel and identify their role. List all members of the Training Advisory Committee (TAC) as Senior/Key Personnel, select Other and list their role as TAC member .

Research & Related (R&R) Budget All instructions in the SF424 (R&R) Application Guide must be followed with the following additional modifications: Use " Senior/Key Person" section for Senior/Key personnel. The salary requested must be commensurate with the salary structure and benefits at the institution where they are employed and within the limits described at https://grants. nih.

gov/grants/policy/salcap_summary. htm . Collaborators may receive appropriate compensation for significant activities on the program, such as recruitment and selection activities, as well as other Other Personnel section to submit costs for salary support for administrative staff.

The salary requested must be commensurate with the salary structure and benefits at the institution where they are employed and within the limits described at https://grants. nih. gov/grants/policy/salcap_summary.

htm . Use Section E for trainee expenses. Travel section to submit costs for key personnel and staff travel that is directly related to the training program and to attend necessary meetings and HIV Research Training Program network meetings usually held in the U.S. Support for senior/key personnel, faculty and collaborators to attend scientific meetings and conferences is not allowed.

Use the Participant/Trainee Support Costs section to submit costs for: Trainees Tuition and Fees for tuition and academic fees at the U.S. or foreign institutions. Include health insurance under Training Related Expenses category rather than in the Tuition/Fees/health insurance Stipend as a subsistence allowance for trainees to help defray living expenses during the training experience.

Medium- and long-term trainees may be paid a stipend comparable to their professional experience and institutional policy. Partial stipends for part time long-term trainees should reflect the amount of time they need to be supported for training in the budget and be described in the budget justification. Living expense for short term trainees should be covered by per diem and included under Trainee Travel.

Trainee Travel to participate in training experiences in other institutions or to attend scientific meetings and workshops that the training program determines to be necessary for the individual’s training. Awards may support travel for current or former trainees to present training-related results at conferences and meetings. Funds may be requested for lodging and per diem at other institutions for short-term trainees.

Do not use the Subsistence category. Use Other to submit costs for Training Related Expenses to help defray other training expenses, such as health insurance (self-only or family, as applicable), trainee project costs, laptop computers and internet connectivity, relevant journal subscriptions and publication costs. Other Direct Costs" to request costs for short- term courses.

Equipment, software and other non-training expenses are not Provide details in the budget justification for expenses requested in each section, and identify, by name, any continuing trainees.

All instructions in the SF424 (R&R) Application Guide PHS 398 Cover Page Supplement All instructions in the SF424 (R&R) Application Guide All instructions in the SF424 (R&R) Application Guide must be followed, with the following additional instructions: Substitute these instructions for those in SF424(R&R) Application Guide: Aims - The specific aims page should: Identify the research infrastructure function and the LMIC institution and, if relevant, the Network and network site at the LMIC institution, for the proposed training.

State concisely the goals of the proposed training and summarize the expected outcome(s), including the impact that the results of the proposed training will exert on the high priority HIV research capacity of the LMIC List succinctly the specific objectives of proposed training.

Strategy: The Research Strategy section must be used to upload the Capacity Building Strategy, which must include the following Provide the rationale for the selection of the specific research Describe the current level of capacity in the selected infrastructure function at the LMIC institution and describe how training will further strengthen that research infrastructure function at the proposed Describe the current HIV research collaborations among the applicant institution, LMIC institution, if relevant the Network, and other participating institution(s) ), and, if relevant, the HIV research Network.

Describe how the selected infrastructure function currently supports the HIV research at the LMIC institution. Identify gaps in that support, and describe how further training will strengthen the LMIC institutional support to HIV research that is considered "high priority" by the LMIC and the NIH.

Indicate how the proposed program relates to prior and current training activities at the proposed training sites, regardless of funding source, that are relevant to the selected infrastructure function.

Provide justification for more training at the LMIC institution, and describe how the proposed training will leverage and support, but not duplicate, other training Describe the institutional support and commitment to the goals of the training program by the applicant, LMIC institution, other partnering institutions and, if relevant, the Network.

Describe strategies that will be used to engage trainees in training-related research infrastructure activities that will directly benefit the on-going priority HIV research at the LMIC institution.

If relevant, describe how the training program will be designed to enable the proposed training sites to become future training sites in the infrastructure function for other LMIC institutions, and, if relevant, other LMIC Network sites and other HIV Research Networks with LMIC sites.

If multiple PD(s)/PI(s) are involved in the training program, describe how the training program and trainees will benefit from the Describe how the leadership and professional staff at the LMIC institution, and, if relevant, the Network site at the LMIC institution were involved in the development of the application. Describe the