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Innovation Matching Grants Program is sponsored by Empire State Development (NYSTAR). This program provides matching funds for New York State small businesses that have received federal Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants. It aims to grow small businesses and support the development of new technologies.
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Empire State Development Announces More Than $3 Million In NYSTAR Innovation Matching Grants Awarded To 28 Small Businesses Advances New York’s Leadership in Innovation by Accelerating Growth and Commercialization Statewide Round 5 Applications Now Open; More Information Here Empire State Development (ESD) today announced more than $3 million in grants have been awarded to 28 New York-based small businesses through Round 4 of the Division of Science, Technology and Innovation (NYSTAR) Innovation Matching Grants program.
The initiative, launched in May 2024, is part of NYSTAR’s ongoing effort to support the growth of small businesses and the development of cutting-edge technologies in New York State. Additionally, ESD announced that Round 5 of the program is now open to qualifying small businesses . To date, NYSTAR has received more than 200 applications, totaling nearly $11 million for 88 businesses.
ESD President, CEO and Commissioner Hope Knight said, "Under Governor Hochul's leadership, New York continues to make strategic investments that nurture and grow the innovation economy all throughout the state. By leveraging state funding with federal research grants, we are helping New York's small businesses move from concept to commercialization quicker, creating companies, jobs and new industries."
The Round 4 awardees represent several strategic technology areas, including additive and manufacturing technologies, artificial intelligence, energy storage and battery technologies, and life sciences and biotechnology.
DirectSeq Biosciences, Inc. — Artificial Intelligence, Life Sciences / Biotechnology | Research and Development in Biotechnology Lighthouse Avionics Inc — Artificial Intelligence, Unmanned Aerial Systems (UAS) / Drones, Sensors | R&D in Physical, Engineering, and Life Sciences ResilienX, Inc. — Artificial Intelligence, Unmanned Aerial Systems (UAS) / Drones | R&D in Physical, Engineering, and Life Sciences Triton Bio, Inc — Food or Agriculture Technology, Life Sciences / Biotechnology, Artificial Intelligence, Sensors | Scientific Research Gallox Semiconductors Inc. — Materials, Semiconductors / Nanotechnology / Nanoelectronics | Semiconductor and Related Device Manufacturing MiTeGen, LLC — Food or Agriculture Technology, Life Sciences / Biotechnology | Irradiation Apparatus Manufacturing Millennial Materials and Devices Inc. (dba Millennial Scientific) — Additive / Manufacturing Technologies, Life Sciences / Biotechnology, Materials | Testing Laboratories SurgiVance, Inc. — Life Sciences / Biotechnology, Artificial Intelligence | Surgical and Medical Instrument Manufacturing Abstractive Health — Artificial Intelligence | R&D in Physical, Engineering, and Life Sciences Advanced Engineering Solutions LLC — Artificial Intelligence, Sensors, Energy Systems, Renewables / Clean / Green Technologies | Computer Systems Design Services AI-Sole, Inc. — Wearable Devices, Artificial Intelligence, Life Sciences / Biotechnology, Sensors | R&D in Physical, Engineering, and Life Sciences Antelope Surgical Solutions Inc — Life Sciences / Biotechnology | Pharmaceutical Preparation Manufacturing Astrabeam LLC — Semiconductors / Nanotechnology / Nanoelectronics, Space Technology, Communications | R&D in Physical, Engineering, and Life Sciences BioWraptor, Inc — Additive / Manufacturing Technologies, Life Sciences / Biotechnology, Renewables / Clean / Green Technologies | Scientific Research Brekland Incorporated — Food or Agriculture Technology, Materials | R&D in Physical, Engineering, and Life Sciences CaroRhythm, Inc. — Wearable Devices, Sensors | Electromedical and Electrotherapeutic Apparatus Manufacturing Cognitive Signals Inc. — Life Sciences / Biotechnology | Electromedical and Electrotherapeutic Apparatus Manufacturing Foli Bio Inc. — Life Sciences / Biotechnology | Scientific Research Killer Snails LLC — Gaming, Augmented Reality / Virtual Reality | All Other Miscellaneous Manufacturing NomoCan Pharmaceuticals, LLC — Life Sciences / Biotechnology | Scientific Research Proactive Life Inc (dba SleepSpace) — Life Sciences / Biotechnology, Artificial Intelligence, Sensors | Scientific R&D Services Tastee Tape — Materials | R&D in Physical, Engineering, and Life Sciences Uncaged Innovations — Materials | Scientific Research Potsdam Sensors LLC (fully owned by TelosAir Corp) — Sensors, Life Sciences / Biotechnology | Automatic Environmental Control Manufacturing IVSonance Biomedical Inc. — Life Sciences / Biotechnology | Electromedical and Electrotherapeutic Apparatus Manufacturing REEgen INC — Life Sciences / Biotechnology, Renewables / Clean / Green Technologies | All Other Professional, Scientific, and Technical Services Empath Medical Innovations (EMI), Inc — Life Sciences / Biotechnology | All Other Miscellaneous Ambulatory Health Care Services EMPRIME THERAPEUTICS INC — Cell or Gene Therapy, Life Sciences / Biotechnology | Biological Product Manufacturing NYSTAR Executive Director Ben Verschueren said, "The Innovation Matching Grants program bridges the gap between R&D and commercialization — the hardest step for many early-stage technology companies.
This state investment gives entrepreneurs the resources to protect and market their intellectual property, attract investors and move their promising projects into everyday use."
Through the Innovation Matching Grants Program, companies that receive funding from the federal government's Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs are eligible for up to $200,000 in matching grants from NYSTAR.
The program ensures that SBIR- and STTR-supported projects in New York State receive additional support for commercialization services not covered by their federal awards, such as marketing and legal assistance. Awards are conditioned on the successful SBIR/STTR federal award and negotiation and execution of a Grant Disbursement Agreement.
NYSTAR’s Innovation Matching Grants program is one of several ways that New York State supports early-stage technology development and accelerates the path from research to market. These efforts directly contribute to business growth, job creation, and stronger regional economies statewide.
NYSTAR’s various resources — including Innovation Matching Grants, Centers of Advanced Technology, Centers of Excellence, Certified Business Incubators, Innovation Hot Spots and Manufacturing Extension Partnership centers — generate nearly $3 billion in economic impact, while creating or retaining almost 10,000 jobs, annually in New York State.
Empire State Development is New York's chief economic development agency, and promotes business growth, job creation, and greater economic opportunity throughout the state. With offices in each of the state's 10 regions, ESD oversees the Regional Economic Development Councils , supports broadband equity through the ConnectALL office, and is growing the workforce of tomorrow through the Office of Strategic Workforce Development.
The agency engages with emerging and next generation industries like clean energy and semiconductor manufacturing looking to grow in New York State, operates a network of assistance centers to help small businesses grow and succeed, and promotes the state's world class tourism destinations through I LOVE NY. For more information, please visit esd. ny.
gov , and connect with ESD on LinkedIn , Facebook and X . About ESD’s Division of Science, Technology and Innovation (NYSTAR) Empire State Development’s Division of Science, Technology and Innovation – known as NYSTAR – advances technology innovation and commercialization in New York State.
NYSTAR offers programs that assist companies from start-up through maturity, leveraging the state’s unparalleled investment in world-class technology assets and expertise. It provides about $70 million annually in funding to support over 80 centers that provide direct assistance to New York State companies — a network of vital assets for enabling technology — and manufacturing-led growth and job creation.
NYSTAR and its partners are proud to contribute to New York’s leadership in the global innovation economy. For more information, visit esd. ny.
gov/nystar . Original link to the article: Click Here
Portal login or registration may be required to access the full application.
According to the current listing, eligibility includes: Small businesses (100 or fewer employees) resident and operating in New York State, actively applying for or having received a Phase I or Phase II SBIR/STTR award from a participating federal agency within the last 12 months. Must remain headquartered and operate or manufacture in New York for at least two years post-commercialization. Confirm the full requirements in the official notice before applying.
The current listing shows up to $100,000 for Phase I; up to $200,000 for Phase II. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Innovation Matching Grants Program is funded by Empire State Development (NYSTAR). Verify program details on the funder's official page before applying.
This opportunity targets applicants in New York. If your organization operates elsewhere, check the official notice for location requirements.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly. Note that portal registration or login may be required before you can access the full application.
Past winners and funding trends for this program
Innovation Matching Grants (IMG) Program is sponsored by Empire State Development (NYSTAR). This program provides matching funds for New York State small businesses that have received federal Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) grants. The funds are intended to expedite commercialization and can cover expenses not allowed under SBIR/STTR, such as business planning, commercialization, patents, and marketing studies. The program aims to grow small businesses and support the development of new technologies in New York State.
Innovation Matching Grants Program (Round 5) is sponsored by Empire State Development (NYSTAR). This program provides matching grants to New York-based small businesses that have received funding from the federal government's Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. The grants provide additional support for commercialization services not covered by federal awards. The program supports various strategic technology areas, including artificial intelligence.
The Main Street Acquisition Support Grant is a grant from the New Jersey Economic Development Authority (NJEDA) that funds reimbursement of closing costs for New Jersey small businesses that have recently purchased commercial property. The program reimburses eligible closing costs up to $50,000 per business for a single location, with a limit of one grant per EIN. Applicants must have closed on a New Jersey commercial property after October 1, 2024, operate from at least 1,000 square feet of the building, meet SBA small business size standards, and be in compliance with New Jersey tax requirements. Applications are accepted on a rolling basis through October 1, 2027.
The New Jersey Manufacturing Voucher Program Phase III is a grant from the New Jersey Economic Development Authority (NJEDA) that funds equipment purchases for New Jersey manufacturers seeking to improve efficiency, productivity, and profitability. This $10,000,000 program provides grants covering a portion of eligible equipment costs, ranging from $7,500 to $250,000 per manufacturer. Priority is given to companies integrating advanced or innovative technologies, processes, and materials. Bonuses are available for certified women-owned, minority-owned, and veteran-owned businesses, firms in opportunity zones, and companies with 50 or fewer full-time employees. Applicants must be for-profit manufacturers in New Jersey with 100 or fewer full-time employees.
Governor Hochul's September 10 solicitation offers up to $25 million in capital grant funding for a Downstate semiconductor design center. Phase 1 concept papers are due October 26, 2026 at 2:00 p.m. The eligibility language excludes for-profit chip firms as prime applicants and the geography excludes everything north of Putnam County. Here is who can actually win this, and how the consortium should be built.
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