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Midcareer Investigator Award in Patient-Oriented Research (Parent K24 - Independent Clinical Trial Not Allowed) is sponsored by National Institute of Mental Health (NIMH), National Institutes of Health (NIH). This award provides protected time for mid-career health-professional doctorates to conduct patient-oriented research (POR) and mentor junior clinical investigators in POR.
This specific funding opportunity is for research that does not involve leading an independent clinical trial. Applicants can, however, propose a research experience in a clinical trial led by a mentor or co-mentor.
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Or search similar grants →According to the current listing, eligibility includes: Applicants must have a health-professional doctoral degree (e.g., MD, DO, DDS, DMD, OD, DC, PharmD, ND, or a doctoral degree in nursing research or practice, clinical psychology, clinical genetics, speech-language pathology, audiology or rehabilitation). They should typically be at the Associate Professor level, have a record of publications, and possess active, peer-reviewed, independent NIMH-funded research support at the time of submission, with the K24 project period overlapping by at least two years with the qualifying NIMH research grant. U.S. domestic institutions are eligible. Confirm the full requirements in the official notice before applying.
The current listing shows up to $50,000 per year for research support, plus salary support commensurate with effort (25-50%) up to NIH cap. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 - Independent Clinical Trial Not Allowed) is funded by National Institute of Mental Health (NIMH), National Institutes of Health (NIH). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program
BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed) is sponsored by National Institute of Mental Health (NIMH), National Institutes of Health (NIH). This funding opportunity supports the establishment of facilities, particularly at minority-serving institutions, to develop and broadly distribute reagent resources for brain cell type-specific access, thereby advancing neuroscience research through innovative neurotechnologies.
School Mental and Behavioral Health: Expanding Access to Evidence-Based Interventions and Services is sponsored by National Institute of Mental Health (NIMH), National Institutes of Health (NIH). This highlighted topic encourages research focused on optimizing and testing school-based mental and behavioral health interventions and service delivery models. It emphasizes research-informed approaches that can be rapidly deployed and sustained in school and afterschool program settings using available resources and personnel. Relevant research includes validating sustainable strategies for operationalizing mental health risk, detecting students at risk, and matching students to appropriate interventions and services, including referring to specialty mental health care when needed.
Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required) is sponsored by National Institute of Mental Health (NIMH), National Institutes of Health (NIH). This funding opportunity supports early-stage, clinically grounded research to create and refine new psychosocial interventions and prevention strategies for mental disorders, with a required clinical trial component. It emphasizes an experimental therapeutics approach, focusing on clearly defined intervention targets and demonstrating target engagement in relation to clinical outcomes. The R61 phase provides up to two years for preliminary testing of target engagement, and the R33 phase provides up to three additional years to replicate target engagement and test its association with changes in clinical outcomes.
The Health and Extreme Weather highlighted topic went live September 1, 2026 with eleven awarding institutes and expires May 1, 2028. There is no set-aside, no separate deadline, and no review criteria — which makes the institute-by-institute language the only real signal, and it is not uniform.
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