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NCI ITCR Advanced Development U24 (RFA-CA-27-020) funds the maturation, enhancement, validation, and dissemination of emerging informatics technologies for cancer research and clinical care. Awards support AI/ML platforms ready to move beyond prototype, including deep learning cancer imaging tools, AI clinical decision support systems, multimodal cancer foundation models, AI-driven genomics pipelines, and digital pathology AI.
Up to $600K direct costs per year for up to 5 years allows substantial software engineering, validation, and community adoption activities. Strong fit for established cancer informatics teams with mature AI prototypes ready for production deployment.
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Or search similar grants →According to the current listing, eligibility includes: U.S. and foreign organizations including universities, nonprofits, small businesses, government agencies, hospitals, and tribal organizations. Multiple PIs permitted. Foreign components allowed. Confirm the full requirements in the official notice before applying.
The current listing shows up to $600,000 direct costs per year for up to 5 years (~$3,000,000 direct costs per project; ~$5M total including indirect costs). Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for NCI ITCR Advanced Development of Informatics Technologies for Cancer Research U24 RFA-CA-27-020 for AI ML Cancer Tools Enhancement and Dissemination are due October 20, 2027. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
NCI ITCR Advanced Development of Informatics Technologies for Cancer Research U24 RFA-CA-27-020 for AI ML Cancer Tools Enhancement and Dissemination is funded by National Cancer Institute (NCI) Informatics Technology for Cancer Research (ITCR) Program. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
NCI ITCR Sustained Support U24 (RFA-CA-27-021) sustains widely-adopted cancer informatics technologies in production use by the cancer research community. Funds operational support, user experience improvement, security and accessibility hardening, and continued community engagement for mature AI/ML tools. Examples include cBioPortal, AI cancer imaging platforms, genomic data commons tools, and clinical informatics platforms. Up to $600K direct costs per year for up to 5 years. Strong fit for teams maintaining open-source cancer AI infrastructure with broad user communities.
The NCI ITCR Early-Stage Development U01 funds the design, prototype, and pilot of novel AI/ML-driven informatics technologies that improve acquisition, management, and/or analysis of data across the cancer research continuum. Funded projects include foundation models for cancer pathology, multimodal cancer foundation models, AI-driven clinical decision support, deep learning tumor microenvironment analysis, and AI clinical trial matching tools. Awards provide up to $300K direct costs per year for up to 3 years. Strong fit for academic medical centers, cancer centers, and informatics labs building open-source AI cancer tools. RFA-CA-27-019 reissues the long-running ITCR program through 2027 with multiple receipt dates.
AHRQ PA-24-261 funds research to determine (1) whether and how breakthrough uses of AI systems affect patient safety in real clinical environments and (2) how AI systems can be safely implemented and used in healthcare delivery. The R18 mechanism funds evaluation - this NOFO explicitly does not support development of new AI systems but rather the rigorous post-deployment evaluation of AI in live clinical settings, complementing AHRQ's broader digital healthcare portfolio. Topics include AI failure mode analysis, alert fatigue from clinical AI, AI-driven diagnostic safety, equity impacts of clinical AI, and human-AI team performance in care delivery. Strong fit for health services researchers, patient safety researchers, and health systems studying AI deployment outcomes.
NIH Research Project Grant Program (R01) is sponsored by National Institutes of Health (NIH). The NIH Research Project Grant Program (R01) supports discrete, specified research projects in health and biomedical research relevant to the mission of the NIH. Foreign institutions are generally eligible to apply for most NIH research project grants.
NIST's MEP Technology Accelerator Pilot puts roughly $20 million behind each of two topics: additive manufacturing for aerospace components and a domestic critical minerals supply chain. Only current MEP Center primary awardees can apply. The NOFO has slipped from Q2 2026 to late 2026, and the public teaming partner list is the single entry point for everyone else.
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